Search Results - "EMERIT, M. B"

Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system by Miquel, M.-C., Emerit, M. B., Nosjean, A., Simon, A., Rumajogee, P., Brisorgueil, M.-J., Doucet, E., Hamon, M., Vergé, D.

“…Following the cloning and sequencing of the A subunit of the 5‐HT3 receptor, two alternatively spliced isoforms, 5‐HT3‐AS and 5‐HT3‐AL, have been identified…”
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Immunolabeling of the rat central nervous system with antibodies partially selective of the short form of the 5-HT3 receptor by DOUCET, E, MIQUEL, M. C, NOSJEAN, A, VERGE, D, HAMON, M, EMERIT, M. B

“…Polyclonal antibodies were raised against a synthetic hexadecapeptide corresponding to the portion of the second intracytoplasmic loop of the short form of the…”
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[3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain by Hall, M D, el Mestikawy, S, Emerit, M B, Pichat, L, Hamon, M, Gozlan, H

“…The specific binding of [3H]8-hydroxy-2-(di-n-propylamino)tetralin ([ 3H]8-OH-DPAT) to 5-hydroxytryptamine (5-HT)-related sites was investigated in several…”
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GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper by Doly, S, Shirvani, H, Gäta, G, Meye, F J, Emerit, M-B, Enslen, H, Achour, L, Pardo-Lopez, L, Yang, S-K, Armand, V, Gardette, R, Giros, B, Gassmann, M, Bettler, B, Mameli, M, Darmon, M, Marullo, S

“…Endoplasmic reticulum (ER) release and cell-surface export of many G protein-coupled receptors (GPCRs) are tightly regulated. For gamma-aminobutyric acid…”
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Immunolabelling of the rat intestinal tract with antibodies specific to the long form of the 5-Hydroxytryptamine3 receptor by DOUCET, E, HAMON, M, EMERIT, M. B

“…The mouse 5-hydroxytryptamine3 (5-HT3) type of serotonin receptors is expressed as two forms, 5-HT3R-A(L) and 5-HT3R-A(S), generated by alternative splicing of…”
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Developmental changes in the differential expression of two serotonin 5-HT3 receptor splice variants in the rat by Miquel, M C, Emerit, M B, Gingrich, J A, Nosjean, A, Hamon, M, el Mestikawy, S

“…PCR was used to isolate identical partial cDNA clones encoding a serotonin 5-HT3 receptor subunit from rat nodose and superior cervical ganglia. The amino acid…”
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Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies by Anzini, Maurizio, Cappelli, Andrea, Vomero, Salvatore, Giorgi, Gianluca, Langer, Thierry, Hamon, Michel, Merahi, Nacera, Emerit, Boris M, Cagnotto, Alfredo, Skorupska, Malgorzata, Mennini, Tiziana, Pinto, Julia C

“…Synthesis and pharmacological evaluation of a series of condensed quinoline derivatives bearing a basic nitrogen on piperazine or [(dimethylamino)ethyl]thio…”
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Physical evidence of the coupling of solubilized 5-HT1A binding sites with G regulatory proteins by Emerit, M B, el Mestikawy, S, Gozlan, H, Rouot, B, Hamon, M

“…Previous investigations (El Mestikawy et al., J Neurochem 51: 1031-1040, 1988) have shown that 5-HT1A binding sites (R[5-HT1A]) solubilized by CHAPS from rat…”
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Cross-talk and Co-trafficking between rho 1/GABA Receptors and ATP-gated Channels by Boue-Grabot, E, Emerit, M B, Toulme, E, Seguela, P, Garret, M

“…gamma -Aminobutyric-acid (GABA) and ATP ionotropic receptors represent two structurally and functionally different classes of neurotransmitter-gated channels…”
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Differentiation alters the expression of the two splice variants of the serotonin 5-HT3 receptor-A mRNA in NG108-15 cells by Emerit, M B, Martres, M P, Miquel, M C, el Mestikawy, S, Hamon, M

“…The serotonin 5-HT3-A receptor (5-HT3R-A) mRNA has been shown recently to be expressed as two forms (5-HT3R-AL and 5-HT3R-AS) varying by the presence or the…”
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The central 5-HT1A receptors: pharmacological, biochemical, functional, and regulatory properties by Hamon, M, Gozlan, H, el Mestikawy, S, Emerit, M B, Bolaños, F, Schechter, L

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Characteristics of [14C]guanidinium accumulation in NG 108-15 cells exposed to serotonin 5-HT3 receptor ligands and substance P by Emerit, M B, Riad, M, Fattaccini, C M, Hamon, M

“…In the presence of substance P (SP; 10 microM), serotonin (5-HT; 1 microM) triggered a cation permeability in cells of the hybridoma (mouse neuroblastoma x rat…”
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Trophic effects of neurotransmitters during brain maturation by Emerit, M B, Riad, M, Hamon, M

“…Besides their neurotransmitter and/or neuromodulatory roles, many neuroactive substances synthesized and released during brain development can also directly…”
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Pharmacological evidence for the involvement of calcium/calmodulin in serotonin 5-HT3 receptor-mediated cation permeability in NG 108-15 cells by Riad, M, Hamon, M, Emerit, M B

“…In NG 108-15 clonal cells, extracellular application of micromolar concentrations of serotonin [5-hydroxytryptamine (5-HT)] and substance P induces the opening…”
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Intracellular Cross Talk and Physical Interaction between Two Classes of Neurotransmitter-Gated Channels by Boue-Grabot, Eric, Barajas-Lopez, Carlos, Chakfe, Yassar, Blais, Dominique, Belanger, Danny, Emerit, Michel B, Seguela, Philippe

“…Fast chemical communications in the nervous system are mediated by several classes of receptor channels believed to be independent functionally and physically…”
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Involvement of tryptophan residue(s) in the specific binding of agonists/antagonists to 5-HT3 receptors in NG108-15 clonal cells by Miquel, M C, Emerit, M B, Gozlan, H, Hamon, M

“…Chemical modification of the 5-HT3 receptors in membranes from NG108-15 hybridoma cells was achieved using protein modifying reagents specific for various…”
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Interaction of S 21007 with 5-HT3 receptors. In vitro and in vivo characterization by DELAGRANGE, P, EMERIT, M. B, MERAHI, N, ABRAHAM, C, MORAIN, P, RAULT, S, RENARD, P, PFEIFFER, B, GUARDINOLA-LEMAITRE, B, HAMON, M

“…The interaction of S 21007 [5-(4-benzyl piperazin-1-yl)4H pyrrolo [1,2-a]thieno[3,2-e]pyrazine] with serotonin 5-HT3 receptors was investigated using…”
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Physicochemical properties of serotonin 5-HT3 binding sites solubilized from membranes of NG 108-15 neuroblastoma-glioma cells by Miquel, M C, Emerit, M B, Bolaños, F J, Schechter, L E, Gozlan, H, Hamon, M

“…Specific binding sites with pharmacological properties typical of serotonin 5-HT3 receptors were identified in membranes of the murine hybridoma cell line NG…”
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The GTP-insensitive component of high-affinity [3H]8-hydroxy-2-(di-n-propylamino)tetralin binding in the rat hippocampus corresponds to an oxidized state of the 5-hydroxytryptamine1A receptor by Emerit, M B, Miquel, M C, Gozlan, H, Hamon, M

“…Previous studies on central 5-hydroxytryptamine1A (5-HT1A) receptors have consistently shown the existence of a GTP-insensitive component of agonist binding,…”
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Irreversible blockade of central 5-HT1A receptor binding sites by the photoaffinity probe 8-methoxy-3'-NAP-amino-PAT by Emerit, M B, Gozlan, H, Marquet, A, Hamon, M

“…A new photoaffinity ligand derived from the potent 5-HT agonist, 8-OH-DPAT, has been synthesized. In the dark, this compound,…”
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