Search Results - "ELVERS, Karen T"

The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease by Avolio, Elisa, Carrabba, Michele, Milligan, Rachel, Kavanagh Williamson, Maia, Beltrami, Antonio P, Gupta, Kapil, Elvers, Karen T, Gamez, Monica, Foster, Rebecca R, Gillespie, Kathleen, Hamilton, Fergus, Arnold, David, Berger, Imre, Davidson, Andrew D, Hill, Darryl, Caputo, Massimo, Madeddu, Paolo

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a broad range of clinical responses including prominent microvascular damage. The…”
Get more information

What is the evidence base to guide surgical treatment of infected hip prostheses? systematic review of longitudinal studies in unselected patients by Beswick, Andrew D, Elvers, Karen T, Smith, Alison J, Gooberman-Hill, Rachael, Lovering, Andrew, Blom, Ashley W

“…Prosthetic joint infection is an uncommon but serious complication of hip replacement. There are two main surgical treatment options, with the choice largely…”
Get full text

Molecular Tracking, through Processing, of Campylobacter Strains Colonizing Broiler Flocks by ELVERS, Karen T, MORRIS, Victoria K, NEWELL, Diane G, ALLEN, Vivien M

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19 by Frost, Joe N, Hamilton, Fergus, Arnold, David, Elvers, Karen T, Shah, Akshay, Armitage, Andrew E, Milne, Alice, McKernon, Jorgen, Attwood, Marie, Chen, Yi-Ling, Xue, Luzheng, Youngs, Jonathan, Provine, Nicholas M, Bicanic, Tihana, Klenerman, Paul, Drakesmith, Hal, Ghazal, Peter

“…Marked reductions in serum iron concentrations are commonly induced during the acute phase of infection. This phenomenon, termed hypoferremia of inflammation,…”
Get full text

Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase by Koulouris, Chloe R., Gardiner, Sian E., Harris, Tessa K., Elvers, Karen T., Mark Roe, S., Gillespie, Jason A., Ward, Simon E., Grubisha, Olivera, Nicholls, Robert A., Atack, John R., Bax, Benjamin D.

“…Human serine racemase (hSR) catalyses racemisation of L-serine to D-serine, the latter of which is a co-agonist of the NMDA subtype of glutamate receptors that…”
Get full text

Oxygen Reactivity of Both Respiratory Oxidases in Campylobacter jejuni: the cydAB Genes Encode a Cyanide-Resistant, Low-Affinity Oxidase That Is Not of the Cytochrome bd Type by JACKSON, Rachel J, ELVERS, Karen T, LEE, Lucy J, GIDLEY, Mark D, WAINWRIGHT, Laura M, LIGHTFOOT, James, PARK, Simon F, POOLE, Robert K

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Effectiveness of physiotherapy exercise following total knee replacement: systematic review and meta-analysis by Artz, Neil, Elvers, Karen T, Lowe, Catherine Minns, Sackley, Cath, Jepson, Paul, Beswick, Andrew D

“…Rehabilitation, with an emphasis on physiotherapy and exercise, is widely promoted after total knee replacement. However, provision of services varies in…”
Get full text

Role of an Inducible Single-Domain Hemoglobin in Mediating Resistance to Nitric Oxide and Nitrosative Stress in Campylobacter jejuni and Campylobacter coli by ELVERS, Karen T, GUANGHUI WU, GILBERTHORPE, Nicola J, POOLE, Robert K, PARK, Simon F

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Antibiotic-induced changes in the human gut microbiota for the most commonly prescribed antibiotics in primary care in the UK: a systematic review by Elvers, Karen T, Wilson, Victoria J, Hammond, Ashley, Duncan, Lorna, Huntley, Alyson L, Hay, Alastair D, van der Werf, Esther T

“…The gut microbiota influences many aspects of human health. We investigated the magnitude and duration of changes in gut microbiota in response to antibiotics…”
Get full text

Pleural Fluid suPAR Levels Predict the Need for Invasive Management in Parapneumonic Effusions by Arnold, David T, Hamilton, Fergus W, Elvers, Karen T, Frankland, Stuart W, Zahan-Evans, Natalie, Patole, Sonia, Medford, Andrew, Bhatnagar, Rahul, Maskell, Nicholas A

“…Parapneumonic effusions have a wide clinical spectrum. The majority settle with conservative management but some progress to complex collections requiring…”
Get full text

A toolkit for the identification of NEAT1_2/paraspeckle modulators by An, Haiyan, Elvers, Karen T, Gillespie, Jason A, Jones, Kimberley, Atack, John R, Grubisha, Olivera, Shelkovnikova, Tatyana A

“…Paraspeckles are ribonucleoprotein granules assembled by NEAT1_2 lncRNA, an isoform of Nuclear Paraspeckle Assembly Transcript 1 (NEAT1). Dysregulation of…”
Get full text

Structures of the Human SPAK and OSR1 Conserved C‐Terminal (CCT) Domains by Elvers, Karen T., Lipka‐Lloyd, Magdalena, Trueman, Rebecca C., Bax, Benjamin D., Mehellou, Youcef

“…STE20/SPS1‐related proline/alanine‐rich kinase (SPAK) and oxidative stress responsive 1 (OSR1) kinase are two serine/threonine protein kinases that regulate…”
Get full text

Local anaesthetic infiltration for peri-operative pain control in total hip and knee replacement: systematic review and meta-analyses of short- and long-term effectiveness by Marques, Elsa M R, Jones, Hayley E, Elvers, Karen T, Pyke, Mark, Blom, Ashley W, Beswick, Andrew D

“…Surgical pain is managed with multi-modal anaesthesia in total hip replacement (THR) and total knee replacement (TKR). It is unclear whether including local…”
Get full text

Development of a Strain-Specific Molecular Method for Quantitating Individual Campylobacter Strains in Mixed Populations by ELVERS, Karen T, HELPS, Christopher R, WASSENAAR, Trudy M, ALLEN, Vivien M, NEWELL, Diane G

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Molecular Methods and Protein Synthesis for Definition of Autoantibody Epitopes by Elvers, Karen T, Williams, Alistair J K

“…Epitope mapping is the process of experimentally identifying the binding sites, or "epitopes," of antibodies on their target antigens. Understanding the…”
Get more information

Growth of Campylobacter jejuni on nitrate and nitrite: electron transport to NapA and NrfA via NrfH and distinct roles for NrfA and the globin Cgb in protection against nitrosative stress by Pittman, Marc S, Elvers, Karen T, Lee, Lucy, Jones, Michael A, Poole, Robert K, Park, Simon F, Kelly, David J

“…Pathways of electron transport to periplasmic nitrate (NapA) and nitrite (NrfA) reductases have been investigated in Campylobacter jejuni, a microaerophilic…”
Get full text

Quorum sensing in Campylobacter jejuni: detection of a luxS encoded signalling molecule by Elvers, Karen T, Park, Simon F

“…School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK 1 Author for correspondence: Simon F. Park. Tel: +44 1483 879024…”
Get full text

The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes by ELVERS, Karen T, GEOGHEGAN, Ivey, SHOEMARK, Debbie K, LAMPASONA, Vito, BINGLEY, Polly J, WILLIAMS, Alistair J. K

“…Cysteines are thought integral to conformational epitopes of islet antigen-2 (IA-2) autoantibodies (IA-2A), possibly through disulfide bond formation. We…”
Get full text

NssR, a member of the Crp‐Fnr superfamily from Campylobacter jejuni, regulates a nitrosative stress‐responsive regulon that includes both a single‐domain and a truncated haemoglobin by Elvers, Karen T., Turner, Sue M., Wainwright, Laura M., Marsden, Gemma, Hinds, Jason, Cole, Jeffrey A., Poole, Robert K., Penn, Charles W., Park, Simon F.

“…Summary Consistent with its role as a nitric oxide (NO)‐detoxifying globin in Campylobacter jejuni, Cgb (Campylobacter globin) expression is strongly and…”
Get full text

A truncated haemoglobin implicated in oxygen metabolism by the microaerophilic food-borne pathogen Campylobacter jejuni by Wainwright, Laura M, Elvers, Karen T, Park, Simon F, Poole, Robert K

“…1 Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield S10 2TN, UK 2 School of Biomedical and Molecular Sciences,…”
Get full text