Search Results - "ELMOSTAFA BAHRAOUI"

HIV and SIV Envelope Glycoproteins Interact with Glycolipids and Lipids by Planes, Rémi, Bahraoui, Elmostafa

“…The present study demonstrates that, in addition to interacting with galactosylceramide (GalCer), HIV-1, HIV-2, and SIV envelope glycoproteins are able to…”
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HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation by Planès, Rémi, Bahraoui, Elmostafa

“…During HIV-1 infection, an increase of indoleamine 2,3 dioxygenase (IDO) expression, and dendritic cells (DC) dysfunction were often associated with AIDS…”
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HIV-1 Tat – TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway by Bahraoui, Elmostafa, Serrero, Manutea, Planès, Rémi

“…In the present study we showed that HIV-1 Tat protein stimulated the expression of Indoleamine 2,3 dioxygenase (IDO) -1 in human monocytes derived dendritic…”
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Special Issue "SARS-CoV-2 Innate and Adaptive Immune Responses" by Planes, Rémi, Bahraoui, Elmostafa

“…Since the end of 2019, humanity has been facing the emergence of a new large positive-sense, single-stranded RNA virus called severe acute respiratory syndrome…”
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SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions by Planès, Rémi, Bert, Jean-Baptiste, Tairi, Sofiane, BenMohamed, Lbachir, Bahraoui, Elmostafa

“…This paper presents a molecular characterization of the interaction between the SARS-CoV-2 envelope (E) protein and TLR2. We demonstrated that the E protein,…”
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Effector memory CD8 T cell response elicits Hepatitis E Virus genotype 3 pathogenesis in the elderly by El Costa, Hicham, Gouilly, Jordi, Abravanel, Florence, Bahraoui, Elmostafa, Peron, Jean-Marie, Kamar, Nassim, Jabrane-Ferrat, Nabila, Izopet, Jacques

“…Genotype 3 Hepatitis E virus (HEV-3) is an emerging threat for aging population. More than one third of older infected patients develops clinical symptoms with…”
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HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway by Ben Haij, Nawal, Planès, Rémi, Leghmari, Kaoutar, Serrero, Manutea, Delobel, Pierre, Izopet, Jacques, BenMohamed, Lbachir, Bahraoui, Elmostafa

“…We recently reported that the human immunodeficiency virus type-1 (HIV-1) Tat protein induced the expression of programmed death ligand-1 (PD-L1) on dendritic…”
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HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes by Planès, Rémi, Ben Haij, Nawal, Leghmari, Kaoutar, Serrero, Manutea, BenMohamed, Lbachir, Bahraoui, Elmostafa

“…In this study, we show that the HIV-1 Tat protein interacts with rapid kinetics to engage the Toll-like receptor 4 (TLR4) pathway, leading to the production of…”
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HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms by Planès, Rémi, BenMohamed, Lbachir, Leghmari, Kaoutar, Delobel, Pierre, Izopet, Jacques, Bahraoui, Elmostafa

“…Chronic human immunodeficiency virus type 1 (HIV-1) infection is associated with induction of T-cell coinhibitory pathways. However, the mechanisms by which…”
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PKC-δ isoform plays a crucial role in Tat-TLR4 signalling pathway to activate NF-κB and CXCL8 production by Serrero, Manutea, Planès, Rémi, Bahraoui, Elmostafa

“…HIV-1 Tat protein induces the production of CXCL8 chemokine in a TLR4/MD2 and PKC dependent manner. The objective of this study was to understand whether these…”
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CXCL17 Chemokine-Dependent Mobilization of CXCR8 + CD8 + Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes by Srivastava, Ruchi, Hernández-Ruiz, Marcela, Khan, Arif A, Fouladi, Mona A, Kim, Grace J, Ly, Vincent T, Yamada, Taikun, Lam, Cynthia, Sarain, Sheilouise A B, Boldbaatar, Undariya, Zlotnik, Albert, Bahraoui, Elmostafa, BenMohamed, Lbachir

“…Circulating conventional memory CD8 T cells (i.e., the CD8 effector memory T [T ] cell and CD8 central memory T [T ] cell subsets) and the noncirculating CD8…”
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High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4 + and CD8 + memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients by Coulon, Pierre-Gregoire, Prakash, Swayam, Dhanushkodi, Nisha R, Srivastava, Ruchi, Zayou, Latifa, Tifrea, Delia F, Edwards, Robert A, Figueroa, Cesar J, Schubl, Sebastian D, Hsieh, Lanny, Nesburn, Anthony B, Kuppermann, Baruch D, Bahraoui, Elmostafa, Vahed, Hawa, Gil, Daniel, Jones, Trevor M, Ulmer, Jeffrey B, BenMohamed, Lbachir

“…Cross-reactive SARS-CoV-2-specific memory CD4 and CD8 T cells are present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However, the…”
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Promoter-Dependent Translation Controlled by p54nrb and hnRNPM during Myoblast Differentiation by Ainaoui, Nadera, Hantelys, Fransky, Renaud-Gabardos, Edith, Bunel, Morgane, Lopez, Frédéric, Pujol, Françoise, Planes, Remi, Bahraoui, Elmostafa, Pichereaux, Carole, Burlet-Schiltz, Odile, Parini, Angelo, Garmy-Susini, Barbara, Prats, Anne-Catherine

“…Fibroblast growth factor 1 (FGF1) is induced during myoblast differentiation at both transcriptional and translational levels. Here, we identify hnRNPM and…”
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Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages by Contreras, Xavier, Mzoughi, Olfa, Gaston, Fabrice, Peterlin, Matija B, Bahraoui, Elmostafa

“…Macrophages, which are CD4 and CCR5 positive, can sustain HIV-1 replication for long periods of time. Thus, these cells play critical roles in the…”
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Tat Protein of Human Immunodeficiency Virus Type 1 Induces Interleukin-10 in Human Peripheral Blood Monocytes: Implication of Protein Kinase C-Dependent Pathway by Badou, A, Bennasser, Y, Moreau, M, Leclerc, C, Benkirane, M, Bahraoui, E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human immunodeficiency virus type 1 Tat protein induces an intracellular calcium increase in human monocytes that requires DHP receptors: involvement in TNF-alpha production by Xavier, Contreras, Yamina, Bennasser, Nathalie, Chazal, Marc, Moreau, Catherine, Leclerc, Jean, Tkaczuk, Elmostafa, Bahraoui

“…HIV-1 Tat protein, acting at the cell membrane, stimulates the production by human monocytes of TNF-α, a cytokine implicated in both HIV-1 replication and…”
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HIV-1 Envelope Glycoproteins Induce the Production of TNF-α and IL-10 in Human Monocytes by Activating Calcium Pathway by Planès, Rémi, Serrero, Manutea, Leghmari, Kaoutar, BenMohamed, Lbachir, Bahraoui, Elmostafa

“…Human HIV-1 infection leads inevitably to a chronic hyper-immune-activation. However, the nature of the targeted receptors and the pathways involved remain to…”
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CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease by Srivastava, Ruchi, Khan, Arif A, Chilukuri, Sravya, Syed, Sabrina A, Tran, Tien T, Furness, Julie, Bahraoui, Elmostafa, BenMohamed, Lbachir

“…Herpes simplex virus 1 (HSV-1) establishes latency within the sensory neurons of the trigeminal ganglia (TG). HSV-specific memory CD8+ T cells play a critical…”
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CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8 + T EM and CD8 + T RM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease by Srivastava, Ruchi, Khan, Arif A, Chilukuri, Sravya, Syed, Sabrina A, Tran, Tien T, Furness, Julie, Bahraoui, Elmostafa, BenMohamed, Lbachir

“…Herpes simplex virus 1 (HSV-1) establishes latency within the sensory neurons of the trigeminal ganglia (TG). HSV-specific memory CD8 T cells play a critical…”
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HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10 by Ben Haij, Nawal, Leghmari, Kaoutar, Planès, Rémi, Thieblemont, Nathalie, Bahraoui, Elmostafa

“…HIV-1 infection results in hyper-immune activation and immunological disorders as early as the asymptomatic stage. Here, we hypothesized that during early…”
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