Search Results - "ELLIS, Ruth D"

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51 by Wu, Yimin, Ellis, Ruth D, Shaffer, Donna, Fontes, Erica, Malkin, Elissa M, Mahanty, Siddhartha, Fay, Michael P, Narum, David, Rausch, Kelly, Miles, Aaron P, Aebig, Joan, Orcutt, Andrew, Muratova, Olga, Song, Guanhong, Lambert, Lynn, Zhu, Daming, Miura, Kazutoyo, Long, Carole, Saul, Allan, Miller, Louis H, Durbin, Anna P

“…Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines…”
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Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria by Ellis, Ruth D, Wu, Yimin, Martin, Laura B, Shaffer, Donna, Miura, Kazutoyo, Aebig, Joan, Orcutt, Andrew, Rausch, Kelly, Zhu, Daming, Mogensen, Anders, Fay, Michael P, Narum, David L, Long, Carole, Miller, Louis, Durbin, Anna P

“…A Phase 1 dose escalating study was conducted in malaria naïve adults to assess the safety, reactogenicity, and immunogenicity of the blood stage malaria…”
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Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial by Hodgson, Susanne H, Choudhary, Prateek, Elias, Sean C, Milne, Kathryn H, Rampling, Thomas W, Biswas, Sumi, Poulton, Ian D, Miura, Kazutoyo, Douglas, Alexander D, Alanine, Daniel GW, Illingworth, Joseph J, de Cassan, Simone C, Zhu, Daming, Nicosia, Alfredo, Long, Carole A, Moyle, Sarah, Berrie, Eleanor, Lawrie, Alison M, Wu, Yimin, Ellis, Ruth D, Hill, Adrian V S, Draper, Simon J

“…The development of effective vaccines against difficult disease targets will require the identification of new subunit vaccination strategies that can induce…”
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Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria by Mullen, Gregory E D, Ellis, Ruth D, Miura, Kazutoyo, Malkin, Elissa, Nolan, Caroline, Hay, Mhorag, Fay, Michael P, Saul, Allan, Zhu, Daming, Rausch, Kelly, Moretz, Samuel, Zhou, Hong, Long, Carole A, Miller, Louis H, Treanor, John

“…Apical Membrane Antigen 1 (AMA1), a polymorphic merozoite surface protein, is a leading blood-stage malaria vaccine candidate. This is the first reported use…”
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A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali by Sagara, Issaka, Dicko, Alassane, Ellis, Ruth D, Fay, Michael P, Diawara, Sory I, Assadou, Mahamadoun H, Sissoko, Mahamadou S, Kone, Mamady, Diallo, Abdoulbaki I, Saye, Renion, Guindo, Merepen A, Kante, Ousmane, Niambele, Mohamed B, Miura, Kazutoyo, Mullen, Gregory E.D, Pierce, Mark, Martin, Laura B, Dolo, Amagana, Diallo, Dapa A, Doumbo, Ogobara K, Miller, Louis H, Saul, Allan

“…Abstract A double blind, randomized, controlled Phase 2 clinical trial was conducted to assess the safety, immunogenicity, and biologic impact of the vaccine…”
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Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults by Ellis, Ruth D, Martin, Laura B, Shaffer, Donna, Long, Carole A, Miura, Kazutoyo, Fay, Michael P, Narum, David L, Zhu, Daming, Mullen, Gregory E D, Mahanty, Siddhartha, Miller, Louis H, Durbin, Anna P

“…Merozoite surface protein 1(42) (MSP1(42)) is a leading blood stage malaria vaccine candidate. In order to induce immune responses that cover the major…”
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Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy? by Duncan, Christopher J.A., Hill, Adrian V.S., Ellis, Ruth D.

“…An effective vaccine against P. falciparum malaria remains a global health priority. Blood-stage vaccines are an important component of this effort, with some…”
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Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine by Ouattara, Amed, Mu, Jianbing, Takala-Harrison, Shannon, Saye, Renion, Sagara, Issaka, Dicko, Alassane, Niangaly, Amadou, Duan, Junhui, Ellis, Ruth D, Miller, Louis H, Su, Xin-zhuan, Plowe, Christopher V, Doumbo, Ogobara K

“…Extensive genetic diversity in vaccine antigens may contribute to the lack of efficacy of blood stage malaria vaccines. Apical membrane antigen-1 (AMA1) is a…”
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A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel® + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults by Sagara, Issaka, Ellis, Ruth D, Dicko, Alassane, Niambele, Mohamed B, Kamate, Beh, Guindo, Ousmane, Sissoko, Mahamadou S, Fay, Michael P, Guindo, Merepen A, Kante, Ousmane, Saye, Renion, Miura, Kazutoyo, Long, Carole, Mullen, Gregory E.D, Pierce, Mark, Martin, Laura B, Rausch, Kelly, Dolo, Amagana, Diallo, Dapa A, Miller, Louis H, Doumbo, Ogobara K

“…Abstract A double blind, randomized and controlled Phase 1 clinical trial was conducted to assess the safety and immunogenicity in malaria-exposed adults of…”
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The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum-Specific Memory B Cells in Malaria-Naive Individuals by Crompton, Peter D, Mircetic, Marko, Weiss, Greta, Baughman, Amy, Huang, Chiung-Yu, Topham, David J, Treanor, John J, Sanz, Inaki, Lee, F. Eun-Hyung, Durbin, Anna P, Miura, Kazutoyo, Narum, David L, Ellis, Ruth D, Malkin, Elissa, Mullen, Gregory E. D, Miller, Louis H, Martin, Laura B, Pierce, Susan K

“…Despite the central role of memory B cells (MBC) in protective immune responses, little is understood about how they are acquired in naive individuals in…”
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Anti-Apical-Membrane-Antigen-1 Antibody Is More Effective than Anti-42-Kilodalton-Merozoite-Surface-Protein-1 Antibody in Inhibiting Plasmodium falciparum Growth, as Determined by the In Vitro Growth Inhibition Assay by Miura, Kazutoyo, Zhou, Hong, Diouf, Ababacar, Moretz, Samuel E, Fay, Michael P, Miller, Louis H, Martin, Laura B, Pierce, Mark A, Ellis, Ruth D, Mullen, Gregory E D, Long, Carole A

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Blood stage vaccines for Plasmodium falciparum: Current status and the way forward by Ellis, Ruth D., Sagara, Issaka, Doumbo, Ogobara, Wu, Yimin

“…Since the recent call for a shift from malaria control to eradication, the role of asexual blood stage vaccines for falciparum malaria, which are not expected…”
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The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum -specific memory B cells in semi-immune adults in Mali by Traore, Boubacar, Koné, Younoussou, Doumbo, Safiatou, Doumtabé, Didier, Traoré, Abdramane, Crompton, Peter D, Mircetic, Marko, Huang, Chiung-Yu, Kayentao, Kassoum, Dicko, Alassane, Sagara, Issaka, Ellis, Ruth D, Miura, Kazutoyo, Guindo, Agnes, Miller, Louis H, Doumbo, Ogobara K, Pierce, Susan K

“…Abstract Antibodies play a key role in controlling blood stage malaria infections, and an effective blood stage malaria vaccine will likely require that it…”
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Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination by Nemes, Elisa, Geldenhuys, Hennie, Rozot, Virginie, Rutkowski, Kathryn T, Ratangee, Frances, Bilek, Nicole, Mabwe, Simbarashe, Makhethe, Lebohang, Erasmus, Mzwandile, Toefy, Asma, Mulenga, Humphrey, Hanekom, Willem A, Self, Steven G, Bekker, Linda-Gail, Ryall, Robert, Gurunathan, Sanjay, DiazGranados, Carlos A, Andersen, Peter, Kromann, Ingrid, Evans, Thomas, Ellis, Ruth D, Landry, Bernard, Hokey, David A, Hopkins, Robert, Ginsberg, Ann M, Scriba, Thomas J, Hatherill, Mark

“…In this phase 2 study, investigators evaluated the potential of two vaccines (H4:IC31 and BCG) to prevent the acquisition of tuberculosis infection and the…”
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Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults by Talaat, Kawsar R, Ellis, Ruth D, Hurd, Janet, Hentrich, Autumn, Gabriel, Erin, Hynes, Noreen A, Rausch, Kelly M, Zhu, Daming, Muratova, Olga, Herrera, Raul, Anderson, Charles, Jones, David, Aebig, Joan, Brockley, Sarah, MacDonald, Nicholas J, Wang, Xiaowei, Fay, Michael P, Healy, Sara A, Durbin, Anna P, Narum, David L, Wu, Yimin, Duffy, Patrick E

“…Transmission-blocking vaccines (TBVs) that target sexual stage parasite development could be an integral part of measures for malaria elimination. Pfs25 is a…”
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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children by Dicko, Alassane, Sagara, Issaka, Ellis, Ruth D, Miura, Kazutoyo, Guindo, Ousmane, Kamate, Beh, Sogoba, Moussa, Niambelé, Mohamed Balla, Sissoko, Mady, Baby, Mounirou, Dolo, Amagana, Mullen, Gregory E D, Fay, Michael P, Pierce, Mark, Diallo, Dapa A, Saul, Allan, Miller, Louis H, Doumbo, Ogobara K

“…Apical Membrane Antigen-1 (AMA1) is one of the leading blood stage malaria vaccine candidates. AMA1-C1/Alhydrogel consists of an equal mixture of recombinant…”
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Non-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay by Miura, Kazutoyo, Perera, Suwani, Brockley, Sarah, Zhou, Hong, Aebig, Joan A, Moretz, Samuel E, Miller, Louis H, Doumbo, Ogobara K, Sagara, Issaka, Dicko, Alassane, Ellis, Ruth D, Long, Carole A

“…Apical membrane antigen 1 (AMA1) is one of the best-studied blood-stage malaria vaccine candidates. When an AMA1 vaccine was tested in a malaria naïve…”
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Comparing the Understanding of Subjects Receiving a Candidate Malaria Vaccine in the United States and Mali by ELLIS, Ruth D, SAGARA, Issaka, FAY, Michael P, DIALLO, Dapa A, DOUMBO, Ogobara K, EMANUEL, Ezekiel J, MILLUM, Joseph, DURBIN, Anna, DICKO, Alassane, SHAFFER, Donna, MILLER, Louis, ASSADOU, Mahamadoun H, KONE, Mamady, KAMATE, Beh, GUINDO, Ousmane

“…Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States…”
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Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine by Ellis, Ruth D, Fay, Michael P, Sagara, Issaka, Dicko, Alassane, Miura, Kazutoyo, Guindo, Merepen A, Guindo, Aldiouma, Sissoko, Mahamadou S, Doumbo, Ogobara K, Diallo, Dapa

“…A Phase 1-2b study of the blood stage malaria vaccine AMA1-C1/Alhydrogel was conducted in 336 children in Donéguébougou and Bancoumana, Mali. In the Phase 2…”
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Diagnostic Accuracy of Early Secretory Antigenic Target-6-Free Interferon-gamma Release Assay Compared to QuantiFERON-TB Gold In-tube by Nemes, Elisa, Abrahams, Deborah, Scriba, Thomas J, Ratangee, Frances, Keyser, Alana, Makhethe, Lebohang, Erasmus, Mzwandile, Mabwe, Simbarashe, Bilek, Nicole, Rozot, Virginie, Geldenhuys, Hennie, Hatherill, Mark, Lempicki, Maria D, Holm, Line Lindebo, Bogardus, Leah, Ginsberg, Ann M, Blauenfeldt, Thomas, Smith, Bronwyn, Ellis, Ruth D, Loxton, Andre G, Walzl, Gerhard, Andersen, Peter, Ruhwald, Morten

“…Early secretory antigenic target-6 (ESAT-6) is an immunodominant Mycobacterium tuberculosis (M.tb) antigen included in novel vaccines against tuberculosis (TB)…”
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