Search Results - "ELLIS, Moira"

Occludin phosphorylation: identification of an occludin kinase in brain and cell extracts as CK2 by Smales, Caroline, Ellis, Moira, Baumber, Rachel, Hussain, Nayer, Desmond, Howard, Staddon, James M

“…In epithelial and endothelial cells, tight junctions limit paracellular flux of ions, proteins and other macromolecules. However, mechanisms regulating tight…”
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Catalytic Domain of Phosphoinositide-specific Phospholipase C (PLC) by Ellis, Moira V., James, Stephen R., Perisic, Olga, Downes, C. Peter, Williams, Roger L., Katan, Matilda

“…Structural studies of phospholipase C δ1 (PLCδ1) in complexes with the inositol-lipid headgroup and calcium identified residues within the catalytic domain…”
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The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold by GRACZYK, Piotr P, KHAN, Afzal, SMALES, Caroline, WHITFIELD, Jonathan, NEAME, Stephen J, SHAH, Bina, WILTON, Daniel, MORGAN, Louise, PATEL, Toshal, CHUNG, Raymond, DESMOND, Howard, STADDON, James M, BHATIA, Gurpreet S, SATO, Nobuaki, INOUE, Atsushi, PALMER, Vanessa, MEDLAND, Darren, NUMATA, Hirotoshi, OINUMA, Hitoshi, CATCHICK, Jacqueline, DUNNE, Angela, ELLIS, Moira

“…Imidazole-based structures of p38 inhibitors served as a starting point for the design of JNK3 inhibitors. Construction of a…”
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Real Time Fluorescence Imaging of PLCγ Translocation and Its Interaction with the Epidermal Growth Factor Receptor by Matsuda, Miho, Paterson, Hugh F., Rodriguez, Rosie, Fensome, Amanda C., Ellis, Moira V., Swann, Karl, Katan, Matilda

“…The translocation of fluorescently tagged PLCγ and requirements for this process in cells stimulated with EGF were analyzed using real time fluorescence…”
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The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5 H-pyrrolo[1,2- a]imidazole scaffold by Graczyk, Piotr P., Khan, Afzal, Bhatia, Gurpreet S., Palmer, Vanessa, Medland, Darren, Numata, Hirotoshi, Oinuma, Hitoshi, Catchick, Jacqueline, Dunne, Angela, Ellis, Moira, Smales, Caroline, Whitfield, Jonathan, Neame, Stephen J., Shah, Bina, Wilton, Daniel, Morgan, Louise, Patel, Toshal, Chung, Raymond, Desmond, Howard, Staddon, James M., Sato, Nobuaki, Inoue, Atsushi

“…The synthesis and neuroprotective properties of three representative enantiomeric pairs ( S)- 2 and ( R)- 2 are reported. Imidazole-based structures of p38…”
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Structural requirements of phosphatidylinositol‐specific phospholipase C δ1 for enzyme activity by ELLIS, Moira V., CARNE, Alexander, KATAN, Matilda

“…Phosphatidylinositol‐specific phospholipase C δ1 isozyme of phosphoinositol‐specific phospholipase C has been used for studies of structural requirements for…”
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Structural requirements of phosphatidylinositol-specific phospholipase C delta 1 for enzyme activity by Ellis, M V, Carne, A, Katan, M

“…Phosphatidylinositol-specific phospholipase C delta 1 isozyme of phosphoinositol-specific phospholipase C has been used for studies of structural requirements…”
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Activated Ki-ras genes in bladder epithelial cell lines transformed by treatment of primary mouse bladder explant cultures with 7,12-dimethylbenz[a]anthracene by Brookes, P, Cooper, C S, Ellis, M V, Warren, W, Gardner, E, Summerhayes, I C

“…DNA from five lines of transformed bladder epithelial cells derived from cultures of primary cells that had been treated with 7,12-dimethylbenz[a]anthracene…”
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Mutation in mammalian cells by isomers of 5-methylchrysene diolepoxide by Brookes, P, Ellis, M V, Pataki, J, Harvey, R G

“…The two pairs of diastereomeric anti- and syn-diolepoxide derivatives of 5-methylchrysene in both bay regions were tested for cytotoxicity and for mutagenicity…”
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