Search Results - "ELLINGROD, Vicki L"

Interaction Between Atypical Antipsychotics and the Gut Microbiome in a Bipolar Disease Cohort by Flowers, Stephanie A., Evans, Simon J., Ward, Kristen M., McInnis, Melvin G., Ellingrod, Vicki L.

“…Objectives The atypical antipsychotic (AAP) class is often associated with metabolic disease, but the mechanistic underpinnings of this risk are not…”
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Effects of cigarette smoking on metabolism and effectiveness of systemic therapy for lung cancer by O'Malley, Meaghan, King, Amanda N, Conte, Marisa, Ellingrod, Vicki L, Ramnath, Nithya

“…Cigarette smoke associated polycyclic aromatic hydrocarbons can induce key drug-metabolizing enzymes of cytochrome P450 and isoforms of the glucuronyl…”
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Antipsychotic-Induced Hyperprolactinemia by Bostwick, Jolene R., Guthrie, Sally K., Ellingrod, Vicki L.

“…Use of antipsychotic agents has been associated with hyperprolactinemia, or elevated prolactin levels; this hormonal abnormality can interfere with the…”
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Gene-specific DNA methylation may mediate atypical antipsychotic-induced insulin resistance by Burghardt, Kyle J, Goodrich, Jacyln M, Dolinoy, Dana C, Ellingrod, Vicki L

“…Objectives Atypical antipsychotics (AAPs) carry a significant risk of cardiometabolic side effects, including insulin resistance. It is thought that the…”
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122 DIAMOND 2.0: Updating a Pioneering Digital Platform for Study Team Workforce Development by Eakin, Brenda, Samuels, Elias, Ellingrod, Vicki L.

“…OBJECTIVES/GOALS: There is a critical need to provide quality training for study teams. Materials need to be flexible and available at the learner’s preferred…”
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Metabolomic signatures associated with weight gain and psychosis spectrum diagnoses: A pilot study by Lee, Jiwon, Costa-Dookhan, Kenya, Panganiban, Kristoffer, MacKenzie, Nicole, Treen, Quinn Casuccio, Chintoh, Araba, Remington, Gary, Müller, Daniel J, Sockalingam, Sanjeev, Gerretsen, Philip, Sanches, Marcos, Karnovsky, Alla, Stringer, Kathleen A, Ellingrod, Vicki L, Tso, Ivy F, Taylor, Stephan F, Agarwal, Sri Mahavir, Hahn, Margaret K, Ward, Kristen M

“…Psychosis spectrum disorders (PSDs), as well as other severe mental illnesses where psychotic features may be present, like bipolar disorder, are associated…”
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Genetic and Metabolite Variability in One-Carbon Metabolism Applied to an Insulin Resistance Model in Patients With Schizophrenia Receiving Atypical Antipsychotics by Ward, Kristen M, Burghardt, Kyle, Kraal, A Zarina, Jaeger, Andrew, Yeomans, Larisa, McHugh, Cora, Karnovsky, Alla, Stringer, Kathleen A, Ellingrod, Vicki L

“…Patients with schizophrenia are at high risk of pre-mature mortality due to cardiovascular disease (CVD). Our group has completed studies in pharmacogenomics…”
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DNA methylation, insulin resistance and second-generation antipsychotics in bipolar disorder by Burghardt, Kyle J, Goodrich, Jacyln M, Dolinoy, Dana C, Ellingrod, Vicki L

“…This study aimed to assess the effect of second-generation antipsychotic (SGA) use and insulin resistance on a global measure of DNA methylation in patients…”
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The Influence of Metabolic Syndrome and Sex on the DNA Methylome in Schizophrenia by Ellingrod, Vicki L., Lines, Brittany N., Goodrich, Jacyln M., Burghardt, Kyle J.

“…Introduction. The mechanism by which metabolic syndrome occurs in schizophrenia is not completely known; however, previous work suggests that changes in DNA…”
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Fats and factors: lipid profiles associate with personality factors and suicidal history in bipolar subjects by Evans, Simon J, Prossin, Alan R, Harrington, Gloria J, Kamali, Masoud, Ellingrod, Vicki L, Burant, Charles F, McInnis, Melvin G

“…Polyunsaturated fatty acids (PUFA) have shown efficacy in the treatment of bipolar disorder, however their specific role in treating the illness is unclear…”
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Reimagining a summer research program during COVID: Strategies for enhancing research workforce diversity by Eakin, Brenda L, Ianni, Phillip A, Byks-Jazayeri, Christy, Ellingrod, Vicki L, Woolford, Susan J

“…Well-designed, accessible short-term research training programs are needed to recruit and retain underrepresented persons into clinical and translational…”
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Implementing and measuring the impact of a clinical and translational research mentor recognition program by Byks-Jazayeri, Christine, Samuels, Elias, Anderson, Elizabeth W, Ellingrod, Vicki L

“…Research shows incentives can motivate faculty to increase their engagement in mentoring, despite a myriad of institutional barriers. One such incentive may be…”
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Indices of Clinical Research Coordinators' Competence by Hornung, Carlton A, Ianni, Phillip A, Jones, Carolynn T, Samuels, Elias M, Ellingrod, Vicki L

“…There is a clear need to educate and train the clinical research workforce to conduct scientifically sound clinical research. Meeting this need requires the…”
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Association between the polymorphic GRM3 gene and negative symptom improvement during olanzapine treatment by Bishop, Jeffrey R., Ellingrod, Vicki L., Moline, Jessica, Miller, Del

“…The excitatory neurotransmitter glutamate has become an important area of focus for schizophrenia researchers. Polymorphisms in the type-three metabotropic…”
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Pharmacogenetics of Selective Serotonin Reuptake Inhibitors and Associated Adverse Drug Reactions by Thomas, Kelan L. H., Ellingrod, Vicki L.

“…The selective serotonin reuptake inhibitors (SSRIs) have become one of the most widely prescribed classes of drugs. They are relatively safe for the…”
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Depressive Symptoms Longitudinally Mediate the Effect of Hyperglycemia on Memory Decline in Type 2 Diabetes by Kraal, A Zarina, Ellingrod, Vicki L, Zahodne, Laura B

“…We sought to examine the mediating role of changes in depressive symptoms in the association between chronic hyperglycemia and longitudinal cognition in a…”
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The Fragile Brain: Stress Vulnerability, Negative Affect and GABAergic Neurocircuits in Psychosis by Taylor, Stephan F, Grove, Tyler B, Ellingrod, Vicki L, Tso, Ivy F

“…Persons with schizophrenia exhibit sensitivity to stress and negative affect (NA), both strongly correlated with poor functional outcome. This theoretical…”
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Association between type-three metabotropic glutamate receptor gene (GRM3) variants and symptom presentation in treatment refractory schizophrenia by Bishop, Jeffrey R., Miller, Del D., Ellingrod, Vicki L., Holman, Timothy

“…Objective Positive associations between polymorphisms in the type‐three metabotropic glutamate receptor gene (GRM3) and the pathogenesis of schizophrenia as…”
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A systematic review of clozapine‐associated inflammation and related monitoring by Leung, Jonathan G., Zhang, Lusi, Markota, Matej, Ellingrod, Vicki L., Gerberi, Danielle J., Bishop, Jeffrey R.

“…Clozapine is an effective antipsychotic medication used for treatment‐resistant schizophrenia. However, it is underutilized due to rigorous hematologic…”
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The DIAMOND portal: An innovative platform for sharing translational research workforce training and assessment resources by Ianni, Phillip A, Perorazio, Thomas E, Samuels, Elias M, Eakin, Brenda L, Jones, Carolynn T, Bigelow, Victoria J, Chung, Haejung, Martina, Camille A, Murphy, Susan L, Rushforth, Alice M, Peyre, Sarah E, Ellingrod, Vicki L

“…Although several initiatives have produced core competency domains for training the translational science workforce, training resources to help clinical…”
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