Search Results - "ELKIN, Sarah"

Endocytic pathways and endosomal trafficking: a primer by Elkin, Sarah R., Lakoduk, Ashley M., Schmid, Sandra L.

“…Summary This brief overview of endocytic trafficking is written in honor of Renate Fuchs, who retires this year. In the mid-1980s, Renate pioneered studies on…”
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British Thoracic Society guideline on pulmonary rehabilitation in adults by Bolton, Charlotte E, Bevan-Smith, Elaine F, Blakey, John D, Crowe, Patrick, Elkin, Sarah L, Garrod, Rachel, Greening, Neil J, Heslop, Karen, Hull, James H, Man, William D-C, Morgan, Michael D, Proud, David, Roberts, C Michael, Sewell, Louise, Singh, Sally J, Walker, Paul P, Walmsley, Sandy

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Rhinovirus Infection Induces Degradation of Antimicrobial Peptides and Secondary Bacterial Infection in Chronic Obstructive Pulmonary Disease by MALLIA, Patrick, FOOTITT, Joseph, MESSAGE, Simon D, ITO, Kazuhiro, BARNES, Peter J, ADCOCK, Ian M, PAPI, Alberto, STANCIU, Luminita A, ELKIN, Sarah L, KON, Onn M, JOHNSON, Malcolm, JOHNSTON, Sebastian L, SOTERO, Rosa, JEPSON, Annette, CONTOLI, Marco, TRUJILLO-TORRALBO, Maria-Belen, KEBADZE, Tatiana, ANISCENKO, Julia, OLESZKIEWICZ, Gregory, GRAY, Katrina

“…Chronic obstructive pulmonary disease (COPD) exacerbations are associated with virus (mostly rhinovirus) and bacterial infections, but it is not known whether…”
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Educational opportunities for postgraduate medical trainees during the COVID-19 pandemic: deriving value from old, new and emerging ways of learning by Kumar, Kartik, Groom, Katherine, Martin, Laura, Russell, Georgina K, Elkin, Sarah L

“…The COVID-19 pandemic has had a significant impact on postgraduate medical training across all specialties. Although some traditional learning opportunities…”
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Ikarugamycin: A Natural Product Inhibitor of Clathrin‐Mediated Endocytosis by Elkin, Sarah R., Oswald, Nathaniel W., Reed, Dana K., Mettlen, Marcel, MacMillan, John B., Schmid, Sandra L.

“…Ikarugamycin (IKA) is a previously discovered antibiotic, which has been shown to inhibit the uptake of oxidized low‐density lipoproteins in macrophages…”
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Impact of a COPD discharge care bundle on readmissions following admission with acute exacerbation: interrupted time series analysis by Laverty, Anthony A, Elkin, Sarah L, Watt, Hilary C, Millett, Christopher, Restrick, Louise J, Williams, Sian, Bell, Derek, Hopkinson, Nicholas S

“…We evaluated the impact of a COPD discharge care bundle on readmission rates following hospitalisation with an acute exacerbation. Interrupted time series…”
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Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD by Footitt, Joseph, PhD, Mallia, Patrick, PhD, Durham, Andrew L., PhD, Ho, W. Eugene, PhD, Trujillo-Torralbo, Maria-Belen, BSc, Telcian, Aurica G., PhD, Del Rosario, Ajerico, BSc, Chang, Cheng, PhD, Peh, Hong-Yong, MSc, Kebadze, Tatiana, MD, Aniscenko, Julia, Stanciu, Luminita, PhD, Essilfie-Quaye, Sarah, PhD, Ito, Kazuhiro, PhD, Barnes, Peter J., FCCP, Elkin, Sarah L., PhD, Kon, Onn M., MD, Wong, W. S. Fred, PhD, Adcock, Ian M., PhD, Johnston, Sebastian L., PhD

“…Background Respiratory virus infections are commonly associated with COPD exacerbations, but little is known about the mechanisms linking virus infection to…”
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Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease by Mallia, Patrick, Webber, Jessica, Gill, Simren K., Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Finney, Lydia, Bakhsoliani, Eteri, Farne, Hugo, Singanayagam, Aran, Footitt, Joseph, Hewitt, Richard, Kebadze, Tatiana, Aniscenko, Julia, Padmanaban, Vijay, Molyneaux, Philip L., Adcock, Ian M., Barnes, Peter J., Ito, Kazihuro, Elkin, Sarah L., Kon, Onn Min, Cookson, William O., Moffat, Miriam F., Johnston, Sebastian L., Tregoning, John S.

“…Patients with chronic obstructive pulmonary disease (COPD) have increased susceptibility to respiratory tract infection, which contributes to disease…”
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Assessing the safety of home oximetry for COVID-19: a multisite retrospective observational study by Clarke, Jonathan, Flott, Kelsey, Fernandez Crespo, Roberto, Ashrafian, Hutan, Fontana, Gianluca, Benger, Jonathan, Darzi, Ara, Elkin, Sarah

“…ObjectivesTo determine the safety and effectiveness of home oximetry monitoring pathways for patients with COVID-19 in the English National Health…”
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A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells by Elkin, Sarah R, Bendris, Nawal, Reis, Carlos R, Zhou, Yunyun, Xie, Yang, Huffman, Kenneth E, Minna, John D, Schmid, Sandra L

“…Metastasis is a multistep process requiring cancer cell signaling, invasion, migration, survival, and proliferation. These processes require dynamic modulation…”
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Designing and implementing a COPD discharge care bundle by Hopkinson, Nicholas S, Englebretsen, Catherine, Cooley, Nicholas, Kennie, Kevin, Lim, Mun, Woodcock, Thomas, Laverty, Anthony A, Wilson, Sandra, Elkin, Sarah L, Caneja, Cielito, Falzon, Christine, Burgess, Helen, Bell, Derek, Lai, Dilys

“…National surveys have revealed significant differences in patient outcomes following admission to hospital with acute exacerbation of COPD which are likely to…”
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Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease by Finney, Lydia, MD, Berry, Matthew, MD, Singanayagam, Aran, MD, Elkin, Sarah L, MD, Johnston, Sebastian L, Prof, Mallia, Patrick, Dr

“…Summary Inhaled corticosteroids are widely used in chronic obstructive pulmonary disease (COPD) and, in combination with long-acting β2 agonists, reduce…”
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Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review by Alboksmaty, Ahmed, Beaney, Thomas, Elkin, Sarah, Clarke, Jonathan M, Darzi, Ara, Aylin, Paul, Neves, Ana-Luísa

“…The COVID-19 pandemic has led health systems to increase the use of tools for monitoring and triaging patients remotely. In this systematic review, we aim to…”
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Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma by Upton, Nadine, Jackson, David J, Nikonova, Alexandra A, Hingley-Wilson, Suzie, Khaitov, Musa, Del Rosario, Ajerico, Traub, Stephanie, Trujillo-Torralbo, Maria-Belen, Habibi, Max, Elkin, Sarah L, Kon, Onn M, Edwards, Michael R, Mallia, Patrick, Footitt, Joseph, Macintyre, Jonathan, Stanciu, Luminita A, Johnston, Sebastian L, Sykes, Annemarie

“…Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses…”
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Targeted Retreatment of Incompletely Recovered Chronic Obstructive Pulmonary Disease Exacerbations with Ciprofloxacin. A Double-Blind, Randomized, Placebo-controlled, Multicenter, Phase III Clinical Trial by Ritchie, Andrew I, Brill, Simon E, Vlies, Ben H, Finney, Lydia J, Allinson, James P, Alves-Moreira, Luana, Wiseman, Dexter J, Walker, Paul P, Baker, Emma, Elkin, Sarah L, Mallia, Patrick, Law, Martin, Donaldson, Gavin C, Calverley, Peter M A, Wedzicha, Jadwiga A

“…Chronic obstructive pulmonary disease (COPD) exacerbations are prone to nonrecovery, but there are no data about the effectiveness of retreatment for these…”
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Chest CT features and functional correlates of COVID-19 at 3 months and 12 months follow-up by Kumar, Kartik, Ratnakumar, Ratnaprashanthika, Collin, Simon M, Berrocal-Almanza, Luis C, Ricci, Piera, Al-Zubaidy, Mustafa, Coker, Robina K, Coleman, Meg, Elkin, Sarah L, Mallia, Patrick, Meghji, Jamilah, Ross, Clare, Russell, Georgina K, Ward, Katie, Wickremasinghe, Melissa, Sheard, Sarah, Copley, Susan J, Kon, Onn Min

“…Long-term pulmonary sequelae of Coronavirus 2019 (COVID-19) remain unclear. Thus, we aimed to establish post-COVID-19 temporal changes in chest computed…”
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Validity of the diagnosis of pneumonia in hospitalised patients with COPD by Finney, Lydia J, Padmanaban, Vijay, Todd, Samuel, Ahmed, Nadia, Elkin, Sarah L, Mallia, Patrick

“…Exacerbations of chronic obstructive pulmonary disease (COPD) and pneumonia are two of the most common reasons for acute hospital admissions. Acute…”
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European cystic fibrosis bone mineralisation guidelines by Sermet-Gaudelus, Isabelle, Bianchi, Maria Luisa, Garabédian, Michèle, Aris, Robert M, Morton, Alison, Hardin, Dana S, Elkin, Sarah L, Compston, Juliet E, Conway, Steven P, Castanet, Mireille, Wolfe, Susan, Haworth, Charles S

“…Abstract Patients with cystic fibrosis (CF) are at risk of developing low bone mineral density (BMD) and fragility fractures. This paper presents consensus…”
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Improving quality in adult long covid services: Findings from the LOCOMOTION quality improvement collaborative by Darbyshire, Julie, Greenhalgh, Trisha, Bakerly, Nawar D., Balasundaram, Kumaran, Baley, Sareeta, Ball, Megan, Bullock, Emily, Cooper, Rowena, Davies, Helen, De Kock, Johannes H., Echevarria, Carlos, Elkin, Sarah, Evans, Rachael, Falope, Zacc, Flynn, Cliodhna, Fraser, Emily, Halpin, Stephen, Jones, Samantha, Lardner, Rachel, Lee, Cassie, Lovett, Ashliegh, Masey, Victoria, Master, Harsha, Mir, Ghazala, Mosley, Adam, Mullard, Jordan, O'Connor, Rory J., Parkin, Amy, Pick, Anton, Scott, Janet, Smith, Nikki, Tucker, Emma, Williams, Paul, Winch, Darren, Wood, Conor, Sivan, Manoj

“…The protracted form of COVID-19 known as ‘long covid’ was first described in 2020. Its symptoms, course and prognosis vary widely; some patients have a…”
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Consensus statement : Guide to bone health and disease in cystic fibrosis by ARIS, Robert M, MERKEL, Peter A, JOSEPH, Patricia M, O'BRIEN, Kimberly, TULLIS, Elizabeth, WATTS, Nelson B, WHITE, Terry B, BACHRACH, Laura K, BOROWITZ, Drucy S, BOYLE, Micheal P, ELKIN, Sarah L, GUISE, Theresa A, HARDIN, Dana S, HAWORTH, Charles S, HOLICK, Michael F

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