Search Results - "EJLERTSEN, Bent"
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The Incidence of Breast Cancer Recurrence 10-32 Years After Primary Diagnosis
Published in JNCI : Journal of the National Cancer Institute (08-03-2022)“…Abstract Background Extended, more effective breast cancer treatments have increased the prevalence of long-term survivors. We investigated the risk of late…”
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2
Neratinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (ExteNET): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Published in The lancet oncology (01-03-2016)“…Summary Background Neratinib, an irreversible tyrosine-kinase inhibitor of HER1, HER2, and HER4, has clinical activity in patients with HER2-positive…”
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3
Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status
Published in Scientific reports (26-01-2021)“…Axillary lymph node status is an important prognostic factor for breast cancer patients and sentinel lymph node biopsy (SLNB) is a less invasive surgical…”
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4
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial
Published in Breast cancer research : BCR (14-05-2020)“…The presence of tumour-infiltrating lymphocytes (TILs) is associated with response to neoadjuvant chemotherapy among patients with triple-negative and…”
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5
Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study
Published in Journal of clinical oncology (10-04-2017)“…Purpose Cholesterol-lowering medication (CLM) has been reported to have a role in preventing breast cancer recurrence. CLM may attenuate signaling through the…”
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HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data
Published in The lancet oncology (01-11-2011)“…Summary Background Prediction of response to anthracycline-based therapy for breast cancer is challenging. We aimed to assess the value of HER2 and TOP2A as…”
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7
Survival outcomes for HER2-low breast cancer: Danish national data
Published in Acta oncologica (14-11-2024)“…Background and purpose: We investigated the prognosis of breast cancer (BC) with low expression of human epidermal growth factor receptor 2 (HER2), as previous…”
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8
Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8·1 years median follow-up
Published in The lancet oncology (01-11-2011)“…Summary Background Postmenopausal women with hormone receptor-positive early breast cancer have persistent, long-term risk of breast-cancer recurrence and…”
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9
Physical deterioration and adaptive recovery in physically inactive breast cancer patients during adjuvant chemotherapy: a randomised controlled trial
Published in Scientific reports (16-06-2020)“…Cardiorespiratory fitness is an independent risk factor for cardiovascular disease and shortened life expectancy in breast cancer survivors. This randomised…”
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10
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Published in Breast cancer research : BCR (27-07-2018)“…The PAM50-based (Prosigna) risk of recurrence (ROR) score and intrinsic subtypes are prognostic for women with high-risk breast cancer. We investigate the…”
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11
High inter-laboratory variability in the assessment of HER2-low breast cancer: a national registry study on 50,714 Danish patients
Published in Breast cancer research : BCR (09-11-2023)“…Abstract Background Considering the recent advancements in the treatment of breast cancer with low expression of human epidermal growth factor receptor 2…”
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12
Socioeconomic position and prognosis in premenopausal breast cancer: a population-based cohort study in Denmark
Published in BMC medicine (30-09-2021)“…Abstract Background To investigate how socioeconomic position (SEP) influences the effectiveness of cancer-directed treatment in premenopausal breast cancer…”
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Correction: Socioeconomic position and prognosis in premenopausal breast cancer: a population-based cohort study in Denmark
Published in BMC medicine (17-08-2023)“…Fig. 2 figure 1 Incidence rates and incidence rate ratios of breast cancer recurrence by socioeconomic position. Abbreviations: CI, Confidence Interval; IR,…”
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14
A catalog of curated breast cancer genes
Published in Breast cancer research and treatment (01-01-2022)“…Purpose Decades of research have identified multiple genetic variants associated with breast cancer etiology. However, there is no database that archives…”
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High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy: Results from the DBCG77B Clinical Trial
Published in Clinical cancer research (15-02-2017)“…Luminal A breast cancers have better prognosis than other molecular subtypes. Luminal A cancers may also be insensitive to adjuvant chemotherapy, although…”
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16
Clinical factors associated with patterns of endocrine therapy adherence in premenopausal breast cancer patients
Published in Breast cancer research : BCR (08-04-2024)“…Patients with hormone receptor positive breast cancer are recommended at least five years of adjuvant endocrine therapy, but adherence to this treatment is…”
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17
Tumour-infiltrating CD4-, CD8- and FOXP3-positive immune cells as predictive markers of mortality in BRCA1- and BRCA2-associated breast cancer
Published in British journal of cancer (09-11-2021)“…Background The prognostic value of tumour-infiltrating lymphocytes (TILs) in breast cancer is well-established. However, the investigation of specific T-cell…”
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18
Incidence and survival of primary metastatic breast cancer in Denmark; implication of breast cancer screening, classification, and staging practice
Published in Acta oncologica (06-05-2024)“…Primary metastatic breast cancer (pMBC) accounts for 5-10% of annual breast cancers with a median survival of 3-4 years, varying among subtypes. In Denmark,…”
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19
A careful reassessment of anthracycline use in curable breast cancer
Published in NPJ breast cancer (08-10-2021)“…It has been over three decades since anthracyclines took their place as the standard chemotherapy backbone for breast cancer in the curative setting. Though…”
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First-Line Treatment of HER2-Positive Metastatic Breast Cancer With Dual Blockade Including Biosimilar Trastuzumab (SB3): Population-Based Real-World Data From the DBCG
Published in Breast cancer : basic and clinical research (2022)“…Purpose: Dual blockade with trastuzumab and pertuzumab in combination with chemotherapy is the recommended first-line therapy for human epidermal growth factor…”
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