Search Results - "EINMAHL, S"
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Development of a new G-CSF product based on biosimilarity assessment
Published in Annals of oncology (01-07-2010)“…Zarzio®, a new recombinant human granulocyte colony-stimulating factor (filgrastim), was evaluated in healthy volunteers and neutropenic patients in phase I…”
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Concomitant and controlled release of dexamethasone and 5-fluorouracil from poly(ortho ester)
Published in International journal of pharmaceutics (20-08-1999)“…A viscous bioerodible and hydrophobic poly(ortho ester) has been developed as a biocompatible, sustained drug release system for an ophthalmic application in…”
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A New Poly(Ortho Ester)-Based Drug Delivery System as an Adjunct Treatment in Filtering Surgery
Published in Investigative ophthalmology & visual science (01-03-2001)“…Pharmacologic modulation of wound healing after glaucoma filtering surgery remains a major clinical challenge in ophthalmology. Poly(ortho ester) (POE) is a…”
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A poly(ortho ester) designed for combined ocular delivery of dexamethasone sodium phosphate and 5-fluorouracil: subconjunctival tolerance and in vitro release
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2000)“…A viscous hydrophobic poly(ortho ester) (POE) has been developed as a biocompatible, biodegradable sustained release system for selected cases of glaucoma…”
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Improved biocompatibility of a viscous bioerodible poly(ortho ester) by controlling the environmental pH during degradation
Published in Biomaterials (01-09-2000)“…The poly(ortho ester), POE, used in this investigation, is a viscous bioerodible polymer (8 kDa), which rapidly degrades into a triol and an acidic by-product,…”
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Evaluation of a Novel Biomaterial in the Suprachoroidal Space of the Rabbit Eye
Published in Investigative ophthalmology & visual science (01-05-2002)“…Drug delivery to treat diseases of the posterior segment of the eye, such as choroidal neovascularization and its complications, is hampered by poor…”
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A viscous bioerodible poly(ortho ester) as a new biomaterial for intraocular application
Published in Journal of biomedical materials research (15-06-2000)“…The biocompatibility of a viscous, hydrophobic, bioerodible poly(ortho ester) (POE) intended for intraocular application was investigated. POE was evaluated as…”
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Therapeutic applications of viscous and injectable poly(ortho esters)
Published in Advanced drug delivery reviews (03-12-2001)“…Poly(ortho esters) (POE) are hydrophobic and bioerodible polymers that have been investigated for pharmaceutical use since the early 1970s. Among the four…”
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Poly(ortho esters) – their development and some recent applications
Published in European Journal of Pharmaceutics and Biopharmaceutics (01-07-2000)“…Poly(ortho esters) have been under development since the early 1970s and four families of such polymers have been described. Of most interest are poly(ortho…”
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Book Review Journal Article -
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Development of a new G-CSF product based on biosimilarity assessment
Published in Annals of oncology (2010)Get full text
Journal Article -
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Ocular biocompatibility of a poly(ortho ester) characterized by autocatalyzed degradation
Published in Journal of biomedical materials research. Part A (01-10-2003)“…The biocompatibility of autocatalyzed poly(ortho ester) (POE70LA30), a viscous, hydrophobic, bioerodible polymer, was investigated. POE70LA30 was synthesized,…”
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Improved biocompatibility of a viscous bioerodible poly(ortho ester) by controllng the environmental pH during degradation
Published in Biomaterials (01-09-2000)“…The poly(ertho ester), POE, used in this investigation, is a viscous bioreodible polymer (8 kDa), which rapidly degrades into a triol and an acidic by-product,…”
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Improved biocompatibility of a viscous bioerodable poly(ortho ester) by controlling the environmental pH during degradation
Published in Biomaterials (01-09-2000)“…The poly(ortho) ester (POE, 8 kDa) used in this study rapidly biodegrades into a triol and acetic acid. In order to improve biocompatibility and prolong both…”
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Treatment of intralocular diseases with poly(ortho ester)-based drug delivery systems
Published in Macromolecular symposia. (01-07-2001)“…A poly(ortho ester) (POE) has been investigated as a carrier for controlled delivery in intraocular therapy. The intraocular biocompatibility of POE was…”
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Poly(Ortho Esters): Recent Developments for Biomedical Applications
Published in Chimia (01-01-2001)“…Poly(ortho esters) (POE) are hydrophobic and bioerodible polymers that have been under development since the early 1970s. Up to now, four generations of such…”
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