Search Results - "EICKMEIER, Olaf"

Impact of CFTR Modulators on the Impaired Function of Phagocytes in Cystic Fibrosis Lung Disease by Meoli, Aniello, Eickmeier, Olaf, Pisi, Giovanna, Fainardi, Valentina, Zielen, Stefan, Esposito, Susanna

“…Cystic fibrosis (CF), the most common genetically inherited disease in Caucasian populations, is a multi-systemic life-threatening autosomal recessive disorder…”
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Pro-resolving lipid mediator Resolvin D1 serves as a marker of lung disease in cystic fibrosis by Eickmeier, Olaf, Fussbroich, Daniela, Mueller, Klaus, Serve, Friederike, Smaczny, Christina, Zielen, Stefan, Schubert, Ralf

“…Cystic fibrosis (CF) is an autosomal recessive genetic disorder that affects multiple organs, including the lungs, pancreas, liver and intestine. Mutations in…”
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Elexacaftor-Tezacaftor-Ivacaftor Treatment Reduces Abdominal Symptoms in Cystic Fibrosis-Early results Obtained With the CF-Specific CFAbd-Score by Mainz, Jochen G, Zagoya, Carlos, Polte, Louise, Naehrlich, Lutz, Sasse, Lenny, Eickmeier, Olaf, Smaczny, Christina, Barucha, Anton, Bechinger, Lilith, Duckstein, Franziska, Kurzidim, Ludwik, Eschenhagen, Patience, Caley, Laura, Peckham, Daniel, Schwarz, Carsten

“…The novel and highly effective CFTR modulator combination of elexacaftor-tezacaftor-ivacaftor (ETI) has been shown to improve lung function and body weight in…”
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Dual Role of microRNA-146a in Experimental Inflammation in Human Pulmonary Epithelial and Immune Cells and Expression in Inflammatory Lung Diseases by Gronau, Lucia, Duecker, Ruth P, Jerkic, Silvija-Pera, Eickmeier, Olaf, Trischler, Jordis, Chiocchetti, Andreas G, Blumchen, Katharina, Zielen, Stefan, Schubert, Ralf

“…microRNA (miR)-146a emerges as a promising post-transcriptional regulator in various inflammatory diseases with different roles for the two isoforms…”
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Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia by Duecker, Ruth, Baer, Patrick, Eickmeier, Olaf, Strecker, Maja, Kurz, Jennifer, Schaible, Alexander, Henrich, Dirk, Zielen, Stefan, Schubert, Ralf

“…Lung failure is responsible for significant morbidity and is a frequent cause of death in ataxia-telangiectasia (A-T). Disturbance in the redox balance of…”
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Corrigendum: Elexacaftor-Tezacaftor-Ivacaftor treatment reduces abdominal symptoms in cystic fibrosis-early results obtained with the CF-specific CFAbd-Score by Mainz, Jochen G, Zagoya, Carlos, Polte, Louise, Naehrlich, Lutz, Sasse, Lenny, Eickmeier, Olaf, Smaczny, Christina, Barucha, Anton, Bechinger, Lilith, Duckstein, Franziska, Kurzidim, Ludwik, Eschenhagen, Patience, Caley, Laura, Peckham, Daniel, Schwarz, Carsten

“…[This corrects the article DOI: 10.3389/fphar.2022.877118.]…”
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Dynamics of abdominal symptoms during the start of a new therapy with elexacaftor/tezacaftor/ivacaftor using the novel CFAbd-day2day questionnaire by Mainz, Jochen G., Barucha, Anton, Huang, Pu, Bechinger, Lilith, Duckstein, Franziska, Polte, Louise, Sadrieh, Pauline, Nährlich, Lutz, Eickmeier, Olaf, Van Dullemen, Suzanne, Eschenhagen, Patience, Schwarz, Carsten, Lüth, Stefan, Zagoya, Carlos, Graepler-Mainka, Ute

“…Background: Elexacaftor–tezacaftor–ivacaftor (ETI) is a novel, highly effective CFTR modulator combination proven to enhance lung function and body weight in…”
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Molecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients by Wetzstein, Nils, Diricks, Margo, Kohl, Thomas A., Wichelhaus, Thomas A., Andres, Sönke, Paulowski, Laura, Schwarz, Carsten, Lewin, Astrid, Kehrmann, Jan, Kahl, Barbara C., Dichtl, Karl, Hügel, Christian, Eickmeier, Olaf, Smaczny, Christina, Schmidt, Annika, Zimmermann, Stefan, Nährlich, Lutz, Hafkemeyer, Sylvia, Niemann, Stefan, Maurer, Florian P., Hogardt, Michael

“…Infections due to Mycobacterium abscessus are a major cause of mortality and morbidity in cystic fibrosis (CF) patients. Furthermore, M. abscessus has been…”
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Immune response, diagnosis and treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis lung disease by Eickmeier, Olaf, Rieber, Nikolaus, Eckrich, Jonas, Hector, Andreas, Graeppler-Mainka, Ute, Hartl, Dominik

“…Patients with cystic fibrosis (CF) suffer from chronic infective lung disease, which determines morbidity and mortality. While bacteria, such as Pseudomonas…”
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Patient Science: Citizen Science Involving Chronically Ill People as Co-Researchers by Heyen, Nils B., Gardecki, Johanna, Eidt-Koch, Daniela, Schlangen, Miriam, Pauly, Sophie, Eickmeier, Olaf, Wagner, Thomas, Bratan, Tanja

“…Citizen science projects in health-related research usually follow a crowdsourcing approach where laypersons primarily have a supplying role in data…”
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Transforming Growth Factor ß1 and Gap Junction Protein Alpha 4 Gene Heterogeneity in Relation to the Severity of Clinical Disease in Cystic Fibrosis by Laubach, Joern Pascal, Ludwig, Michael, Horn, Tabea, Eickmeier, Olaf, Smaczny, Christina, Schubert, Ralf, Zielen, Stefan, Majoor, Christof, Aydin, Malik, Schnell, Alexander, Schmitt-Grohé, Sabina

“…High TGFβ1-producing variants cause severe clinical disease in F508del homozygous patients. Lately, we showed that a single nucleotide polymorphism (SNP),…”
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Impact of a Gap Junction Protein Alpha 4 Variant on Clinical Disease Phenotype in F508del Homozygous Patients With Cystic Fibrosis by Horn, Tabea, Ludwig, Michael, Eickmeier, Olaf, Neerinex, Anne H, Maitland-van der Zee, Anke H, Smaczny, Christina, Wagner, Thomas O F, Schubert, Ralf, Zielen, Stefan, Majoor, Christof, Bos, Lieuwe D, Schmitt-Grohé, Sabina

“…Lung disease phenotype varies widely even in the (homozygous) genotype. Leukocyte-driven inflammation is important for pulmonary disease pathogenesis in cystic…”
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Coil embolisation for massive haemoptysis in cystic fibrosis by Dohna, Martha, Renz, Diane Miriam, Stehling, Florian, Dohna-Schwake, Christian, Sutharsan, Sivagurunathan, Neurohr, Claus, Wirtz, Hubert, Eickmeier, Olaf, Grosse-Onnebrink, Jörg, Sauerbrey, Axel, Soditt, Volker, Poplawska, Krystyna, Wacker, Frank, Montag, Michael Johannes

“…IntroductionMassive haemoptysis is a life-threatening event in advanced cystic fibrosis (CF) lung disease with bronchial artery embolisation (BAE) as standard…”
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The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease by Hector, Andreas, Kormann, Michael S D, Mack, Ines, Latzin, Philipp, Casaulta, Carmen, Kieninger, Elisabeth, Zhou, Zhe, Yildirim, Ali Ö, Bohla, Alexander, Rieber, Nikolaus, Kappler, Matthias, Koller, Barbara, Eber, Ernst, Eickmeier, Olaf, Zielen, Stefan, Eickelberg, Oliver, Griese, Matthias, Mall, Marcus A, Hartl, Dominik

“…The chitinase-like protein YKL-40 was found to be increased in patients with severe asthma and chronic obstructive pulmonary disease (COPD), two disease…”
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Mannose-Binding Lectin (MBL) and Gap Junction Protein Alpha 4 (GJA4) Gene Heterogeneity in Relation to Severity of Clinical Disease in Cystic Fibrosis by Laubach, Joern Pascal, Ludwig, Michael, Horn, Tabea, Eickmeier, Olaf, Smaczny, Christina, Schubert, Ralf, Zielen, Stefan, Majoor, Christof, Aydin, Malik, Schmitt-Grohé, Sabina

“…BACKGROUNDRecently, we provided evidence that a single nucleotide polymorphism (SNP), rs41266431, on the gap junction protein alpha 4 (GJA4) gene, acts as a…”
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Proinflammatory pattern in the lower airways of non-asthmatic obese adolescents by Gutmann, Desiree, Dressler, Melanie, Eickmeier, Olaf, Herrmann, Eva, Kirwil, Marta, Schubert, Ralf, Zielen, Stefan, Zissler, Ulrich M

“…Obesity is known to be a pro-inflammatory condition affecting multiple organs. Obesity as a systemic pro-inflammatory state, might be associated with bronchial…”
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Progress in Definition, Prevention and Treatment of Fungal Infections in Cystic Fibrosis by Schwarz, Carsten, Hartl, Dominik, Eickmeier, Olaf, Hector, Andreas, Benden, Christian, Durieu, Isabelle, Sole, Amparo, Gartner, Silvia, Milla, Carlos E., Barry, Peter James

“…Cystic fibrosis (CF) is a chronic lethal multi-system condition; however, most of the morbidity and mortality is dependent on the status of the respiratory…”
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Comparison of the Lung Clearance Index in Preschool Children With Primary Ciliary Dyskinesia and Cystic Fibrosis by Roehmel, Jobst F., Doerfler, Friederike J., Koerner-Rettberg, Cordula, Brinkmann, Folke, Schlegtendal, Anne, Wetzke, Martin, Rudolf, Isa, Helms, Simone, Große-Onnebrink, Joerg, Yu, Yin, Nuesslein, Thomas, Wojsyk-Banaszak, Irena, Becker, Sebastian, Eickmeier, Olaf, Sommerburg, Olaf, Omran, Heymut, Stahl, Mirjam, Mall, Marcus A.

“…Previous studies showed that the lung clearance index (LCI) determined by multiple-breath washout (MBW) is sensitive to detecting early lung disease in…”
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Inflammation biomarkers in sputum for clinical trials in cystic fibrosis: current understanding and gaps in knowledge by Lepissier, Agathe, Addy, Charlotte, Hayes, Kate, Noel, Sabrina, Bui, Stéphanie, Burgel, Pierre-Régis, Dupont, Lieven, Eickmeier, Olaf, Fayon, Michael, Leal, Teresinha, Lopes, Carlos, Downey, Damian G., Sermet-Gaudelus, Isabelle

“…Sputum biomarkers hold promise as a direct measure of inflammation within the cystic fibrosis (CF) lung, but variability in study design and sampling…”
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Clinical relevance of Aspergillus fumigatus sensitization in cystic fibrosis by Eickmeier, Olaf, Zissler, Ulrich M., Wittschorek, Julia, Unger, Frederike, Schmitt‐Grohé, Sabina, Schubert, Ralf, Herrmann, Eva, Zielen, Stefan

“…Rationale The clinical relevance of sensitization to Aspergillus (A) fumigatus in cystic fibrosis (CF) is unclear. Some researchers propose that specific A…”
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