Search Results - "EHLERT, E"

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection by Hellström, M, Ruitenberg, M J, Pollett, M A, Ehlert, E M E, Twisk, J, Verhaagen, J, Harvey, A R

“…Recombinant adeno-associated virus (rAAV) vectors are increasingly being used as tools for gene therapy, and clinical trials have begun in patients with…”
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CXC chemokines in angiogenesis by Belperio, John A., Keane, Michael P., Arenberg, Douglas A., Addison, Christina L., Ehlert, Jan E., Burdick, Marie D., Strieter, Robert M.

“…A variety of factors have been identified that regulate angiogenesis, including the CXC chemokine family. The CXC chemokines are a unique family of cytokines…”
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Markedly divergent effects of Ouabain on a Temozolomide-resistant (T98G) vs. a Temozolomide-sensitive (LN229) Glioblastoma cell line by Weidemann, Heidrun, Feger, Daniel, Ehlert, Jan E., Menger, Marcus M., Krempien, Robert C.

“…Background Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis. GMB are highly recurrent mainly because of radio- and…”
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Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons by Mason, Matthew RJ, Ehlert, Erich ME, Eggers, Ruben, Pool, Chris W, Hermening, Stephan, Huseinovic, Angelina, Timmermans, Eric, Blits, Bas, Verhaagen, Joost

“…For many experiments in the study of the peripheral nervous system, it would be useful to genetically manipulate primary sensory neurons. We have compared…”
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The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity by Addison, Christina L, Daniel, Thomas O, Burdick, Marie D, Liu, Hua, Ehlert, Jan E, Xue, Ying Ying, Buechi, Linda, Walz, Alfred, Richmond, Ann, Strieter, Robert M

“…We have previously shown that members of the ELR(+) CXC chemokine family, including IL-8; growth-related oncogenes alpha, beta, and gamma; granulocyte…”
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A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation by Eggers, R., Tannemaat, M.R., Ehlert, E.M., Verhaagen, J.

“…Reimplantation of avulsed rat lumbar spinal ventral roots results in poor recovery of function of the denervated hind limb muscles. In contrast, reimplantation…”
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Bottom-Up Fabrication of DNA-Templated Electronic Nanomaterials and Their Characterization by Pang, Chao, Aryal, Basu R, Ranasinghe, Dulashani R, Westover, Tyler R, Ehlert, Asami E F, Harb, John N, Davis, Robert C, Woolley, Adam T

“…Bottom-up fabrication using DNA is a promising approach for the creation of nanoarchitectures. Accordingly, nanomaterials with specific electronic, photonic,…”
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The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation by Brandt, Ernst, Petersen, Frank, Ludwig, Andreas, Ehlert, Jan E., Bock, Lothar, Flad, Hans‐D.

“…The recruitment of neutrophil granulocytes to sites of tissue injury is one of the earliest events during host defense. Several chemotactic cytokines belonging…”
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Thrombocidins, Microbicidal Proteins from Human Blood Platelets, Are C-terminal Deletion Products of CXC Chemokines by Krijgsveld, Jeroen, Zaat, Sebastian A.J., Meeldijk, Jan, van Veelen, Peter A., Fang, Gang, Poolman, Bert, Brandt, Ernst, Ehlert, Jan E., Kuijpers, Alma J., Engbers, Gerard H.M., Feijen, Jan, Dankert, Jacob

“…Antibacterial proteins are components of the innate immune system found in many organisms and produced by a variety of cell types. Human blood platelets…”
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Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons by Hellström, M., Muhling, J., Ehlert, E.M., Verhaagen, J., Pollett, M.A., Hu, Y., Harvey, A.R.

“…Intravitreal injections of recombinant ciliary neurotrophic factor (rCNTF) protect adult rat retinal ganglion cells (RGCs) after injury and stimulate…”
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GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors by Aartsen, Wendy M, van Cleef, Koen W R, Pellissier, Lucie P, Hoek, Robert M, Vos, Rogier M, Blits, Bas, Ehlert, Erich M E, Balaggan, Kamaljit S, Ali, Robin R, Verhaagen, Joost, Wijnholds, Jan

“…Müller cell gliosis occurs in various retinal pathologies regardless of the underlying cellular defect. Because activated Müller glial cells span the entire…”
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Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains by Dick, Gunnar, Tan, Chin Lik, Alves, Joao Nuno, Ehlert, Erich M.E., Miller, Gregory M., Hsieh-Wilson, Linda C., Sugahara, Kazuyuki, Oosterhof, Arie, van Kuppevelt, Toin H., Verhaagen, Joost, Fawcett, James W., Kwok, Jessica C.F.

“…Chondroitin sulfate (CS) and the CS-rich extracellular matrix structures called perineuronal nets (PNNs) restrict plasticity and regeneration in the CNS…”
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Baculovirus Infection of Nondividing Mammalian Cells: Mechanisms of Entry and Nuclear Transport of Capsids by van Loo, N D, Fortunati, E, Ehlert, E, Rabelink, M, Grosveld, F, Scholte, B J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impact of oral vitamin C on histamine levels and seasickness by Jarisch, R, Weyer, D, Ehlert, E, Koch, C H, Pinkowski, E, Jung, P, Kähler, W, Girgensohn, R, Kowalski, J, Weisser, B, Koch, A

“…Seasickness is a risk aboard a ship. Histamine is postulated as a causative agent, inversely related to the intake of vitamin C. Persons with mastocytosis…”
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Influence of Orally Taken Vitamin C on Histamine Levels and Motion Sickness by Jarisch, R, Weyer, D, Ehlert, E, Koch, C, Pinkowski, E, Jung, P, Kähler, W, Girgensohn, R, Hemmer, W, Koch, A

“…There is an inverse relation between histamine and vitamin C. We investigated the influence of orally taken vitamin C on the prevention of motion sickness…”
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The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain by Vo, Tam, Carulli, Daniela, Ehlert, Erich M.E., Kwok, Jessica C.F., Dick, Gunnar, Mecollari, Vasil, Moloney, Elizabeth B., Neufeld, Gera, de Winter, Fred, Fawcett, James W., Verhaagen, Joost

“…In the adult rodent brain, subsets of neurons are surrounded by densely organised extracellular matrix called perineuronal nets (PNNs). PNNs consist of…”
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Identification of Distinct Surface-Expressed and Intracellular CXC-Chemokine Receptor 2 Glycoforms in Neutrophils: N-Glycosylation Is Essential for Maintenance of Receptor Surface Expression by Ludwig, Andreas, Ehlert, Jan E, Flad, Hans-Dieter, Brandt, Ernst

“…The G protein-coupled CXC-chemokine receptor CXCR-2 mediates activation of neutrophil effector functions in response to multiple ligands, including IL-8 and…”
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Membrane Targeting of cGMP-Dependent Protein Kinase is Required for Cystic Fibrosis Transmembrane Conductance Regulator Cl-Channel Activation by Arie. B. Vaandrager, Smolenski, Albert, Tilly, Ben C., Houtsmuller, Adriaan B., Ehrich M. E. Ehlert, Alice G. M. Bot, Edixhoven, Marcel, Wendy E. M. Boomaars, Lohmann, Suzanne M., De Jonge, Hugo R.

“…A recently cloned isoform of cGMP-dependent protein kinase (cGK), designated type II, was implicated as the mediator of cGMP-provoked intestinal Cl-secretion…”
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Down-regulation of neutrophil functions by the ELR+CXC chemokine platelet basic protein by Ehlert, Jan E., Ludwig, Andreas, Grimm, Tobias A., Lindner, Buko, Flad, Hans-Dieter, Brandt, Ernst

“…The platelet-derived neutrophil-activating peptide 2 (NAP-2, 70 amino acids) belongs to the ELR+ CXC subfamily of chemokines. Similar to other members of this…”
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Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases by Thaher, Bassam Abu, Arnsmann, Martina, Totzke, Frank, Ehlert, Jan E, Kubbutat, Michael H. G, Schächtele, Christoph, Zimmermann, Markus O, Koch, Pierre, Boeckler, Frank M, Laufer, Stefan A

“…In the course of searching for new p38α MAP kinase inhibitors, we found that the regioisomeric switch from…”
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