Search Results - "EGLI, Adrian"

Combination of Whole Genome Sequencing and Metagenomics for Microbiological Diagnostics by Purushothaman, Srinithi, Meola, Marco, Egli, Adrian

“…Whole genome sequencing (WGS) provides the highest resolution for genome-based species identification and can provide insight into the antimicrobial resistance…”
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Evolution of Antibiotic Tolerance Shapes Resistance Development in Chronic Pseudomonas aeruginosa Infections by Santi, Isabella, Manfredi, Pablo, Maffei, Enea, Egli, Adrian, Jenal, Urs

“…The widespread use of antibiotics promotes the evolution and dissemination of resistance and tolerance mechanisms. To assess the relevance of tolerance and its…”
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Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut by Bakkeren, Erik, Huisman, Jana S., Fattinger, Stefan A., Hausmann, Annika, Furter, Markus, Egli, Adrian, Slack, Emma, Sellin, Mikael E., Bonhoeffer, Sebastian, Regoes, Roland R., Diard, Médéric, Hardt, Wolf-Dietrich

“…The emergence of antibiotic-resistant bacteria through mutations or the acquisition of genetic material such as resistance plasmids represents a major public…”
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Time-calibrated phylogenetic and chromosomal mobilome analyses of Staphylococcus aureus CC398 reveal geographical and host-related evolution by Fernandez, Javier Eduardo, Egli, Adrian, Overesch, Gudrun, Perreten, Vincent

“…An international collection of Staphylococcus aureus of clonal complex (CC) 398 from diverse hosts spanning all continents and a 30 year-period is studied…”
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Prevalence of Polyomavirus BK and JC Infection and Replication in 400 Healthy Blood Donors by Egli, Adrian, Infanti, Laura, Dumoulin, Alexis, Buser, Andreas, Samaridis, Jacqueline, Stebler, Christine, Gosert, Rainer, Hirsch, Hans H.

“…BackgroundThe replication of BK virus (BKV) and JC virus (JCV) is linked to polyomavirus-associated nephropathy, hemorrhagic cystitis, and multifocal…”
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Interferon-λ Enhances the Differentiation of Naive B Cells into Plasmablasts via the mTORC1 Pathway by Syedbasha, Mohammedyaseen, Bonfiglio, Ferdinando, Linnik, Janina, Stuehler, Claudia, Wüthrich, Daniel, Egli, Adrian

“…Type III interferon (interferon lambda [IFN-λ]) is known to be a potential immune modulator, but the mechanisms behind its immune-modulatory functions and its…”
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Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication by Maffei, Enea, Woischnig, Anne-Kathrin, Burkolter, Marco R., Heyer, Yannik, Humolli, Dorentina, Thürkauf, Nicole, Bock, Thomas, Schmidt, Alexander, Manfredi, Pablo, Egli, Adrian, Khanna, Nina, Jenal, Urs, Harms, Alexander

“…Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-growing laboratory cultures of their bacterial hosts. However,…”
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Factors Associated With MALDI-TOF Mass Spectral Quality of Species Identification in Clinical Routine Diagnostics by Cuénod, Aline, Foucault, Frédéric, Pflüger, Valentin, Egli, Adrian

“…An accurate and timely identification of bacterial species is critical in clinical diagnostics. Species identification allows a potential first adaptation of…”
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PCR performance in the SARS-CoV-2 Omicron variant of concern? by Metzger, César M J A, Lienhard, Reto, Seth-Smith, Helena M B, Roloff, Tim, Wegner, Fanny, Sieber, Jonas, Bel, Michael, Greub, Gilbert, Egli, Adrian

“…The new SARS-CoV-2 Omicron variant (B.1.1.529) has been recently declared a Variant of Concern due to a series of important mutations in the viral spike…”
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Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations by Marzolini, Catia, Stader, Felix, Stoeckle, Marcel, Franzeck, Fabian, Egli, Adrian, Bassetti, Stefano, Hollinger, Alexa, Osthoff, Michael, Weisser, Maja, Gebhard, Caroline E, Baettig, Veronika, Geenen, Julia, Khanna, Nina, Tschudin-Sutter, Sarah, Mueller, Daniel, Hirsch, Hans H, Battegay, Manuel, Sendi, Parham

“…Coronavirus disease 2019 (COVID-19) leads to inflammatory cytokine release, which can downregulate the expression of metabolizing enzymes. This cascade affects…”
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Dissociations of oral foci of infections with infectious complications and survival after haematopoietic stem cell transplantation by Mauramo, Matti, Grolimund, Patricia, Egli, Adrian, Passweg, Jakob, Halter, Jörg, Waltimo, Tuomas

“…Haematopoietic stem cell transplantation (HSCT) recipients are at increased risk for severe infections. This study examined the associations of common oral…”
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Influenza vaccination of cancer patients during PD-1 blockade induces serological protection but may raise the risk for immune-related adverse events by Läubli, Heinz, Balmelli, Catharina, Kaufmann, Lukas, Stanczak, Michal, Syedbasha, Mohammedyaseen, Vogt, Dominik, Hertig, Astrid, Müller, Beat, Gautschi, Oliver, Stenner, Frank, Zippelius, Alfred, Egli, Adrian, Rothschild, Sacha I

“…Immune checkpoint inhibiting antibodies were introduced into routine clinical practice for cancer patients. Checkpoint blockade has led to durable remissions…”
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Self-testing for SARS-CoV-2: importance of lay communication by Coste, Alix T., Egli, Adrian, Greub, Gilbert

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Functional Activity of the Complement System in Hospitalized COVID-19 Patients: A Prospective Cohort Study by Charitos, Panteleimon, Heijnen, Ingmar A F M, Egli, Adrian, Bassetti, Stefano, Trendelenburg, Marten, Osthoff, Michael

“…Although the exact factors promoting disease progression in COVID-19 are not fully elucidated, unregulated activation of the complement system (CS) seems to…”
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Predictors of infectious meningitis or encephalitis: the yield of cerebrospinal fluid in a cross-sectional study by Dittrich, Tolga, Marsch, Stephan, Egli, Adrian, Rüegg, Stephan, De Marchis, Gian Marco, Tschudin-Sutter, Sarah, Sutter, Raoul

“…Cerebrospinal fluid (CSF) analyses are recommended in patients with meningitis and/or encephalitis, but evidence regarding its diagnostic yield is low. We…”
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Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay by Goldenberger, Daniel, Leuzinger, Karoline, Sogaard, Kirstine K., Gosert, Rainer, Roloff, Tim, Naegele, Klaudia, Cuénod, Aline, Mari, Alfredo, Seth-Smith, Helena, Rentsch, Katharina, Hinić, Vladimira, Hirsch, Hans H., Egli, Adrian

“…The clinical and epidemiologic management of the SARS-CoV-2 pandemic is critically dependent on molecular assays with short turn-around time. We validated the…”
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A Cross-Sectional Study of Colonization Rates with Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-Lactamase (ESBL) and Carbapenemase-Producing Enterobacteriaceae in Four Swiss Refugee Centres by Piso, Rein Jan, Käch, Roman, Pop, Roxana, Zillig, Daniela, Schibli, Urs, Bassetti, Stefano, Meinel, Dominik, Egli, Adrian

“…The recent crisis of refugees seeking asylum in European countries challenges public health on many levels. Most refugees currently arrive from Syria,…”
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The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections by Egli, Adrian, Santer, Deanna M, O'Shea, Daire, Tyrrell, D Lorne, Houghton, Michael

“…Type-III interferons (IFN-λ, IFNL) are the most recently described family of IFNs. This family of innate cytokines are increasingly being ascribed pivotal…”
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Nosocomial transmission of a blaVIM-2 carbapenemase integron between isolates of two different Pseudomonas species by Büchler, Andrea C, Wüthrich, Daniel, Jauslin, Melanie Wicki, Egli, Adrian, Widmer, Andreas F

“…We report the first documented in-hospital patient-to-patient-transmission of a blaVIM-2 integron between isolates of Pseudomonas alcaligenes and P…”
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SARS-CoV-2 outbreak in a tri-national urban area is dominated by a B.1 lineage variant linked to a mass gathering event by Stange, Madlen, Mari, Alfredo, Roloff, Tim, Seth-Smith, Helena Mb, Schweitzer, Michael, Brunner, Myrta, Leuzinger, Karoline, Søgaard, Kirstine K, Gensch, Alexander, Tschudin-Sutter, Sarah, Fuchs, Simon, Bielicki, Julia, Pargger, Hans, Siegemund, Martin, Nickel, Christian H, Bingisser, Roland, Osthoff, Michael, Bassetti, Stefano, Schneider-Sliwa, Rita, Battegay, Manuel, Hirsch, Hans H, Egli, Adrian

“…The first case of SARS-CoV-2 in Basel, Switzerland was detected on February 26th 2020. We present a phylogenetic study to explore viral introduction and…”
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