Search Results - "EDLUND, T"
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1
IPF1, a homeodomain‐containing transactivator of the insulin gene
Published in The EMBO journal (01-11-1993)“…We describe the cloning of insulin promoter factor 1 (IPF1), a homeodomain protein which in the adult mouse pancreas is selectively expressed in the beta‐cells…”
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2
Mice Lacking Extracellular Superoxide Dismutase are More Sensitive to Hyperoxia
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-1995)“…Extracellular superoxide dismutase (EC-SOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) is a secreted Cu- and Zn-containing tetrameric glycoprotein, the…”
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3
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes
Published in Cell (16-12-1994)“…Motor neurons located at different positions in the embryonic spinal cord innervate distinct targets in the periphery, establishing a topographic neural map…”
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4
Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube
Published in Cell (02-06-1995)“…The vertebrate hedgehog-related gene Sonic hedge-hog (Shh) is expressed in ventral domains along the entire rostrocaudal length of the neural tube, including…”
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5
Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary
Published in Development (Cambridge) (15-03-1998)“…The mechanisms by which inductive signals control the identity, proliferation and timing of differentiation of progenitor cells in establishing spatial pattern…”
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6
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
Published in Cell (25-02-1994)“…The differentiation of distinct cell types in the ventral neural tube depends on local inductive signals from the notochord. We have isolated a vertebrate…”
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7
Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation
Published in Development (Cambridge) (01-06-1993)“…Isl-1 has previously been established as the earliest marker of developing chicken spinal motor neurons where it is regulated by inductive signals from the…”
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8
Sonic hedgehog signaling at gastrula stages specifies ventral telencephalic cells in the chick embryo
Published in Development (Cambridge) (01-08-2000)“…A secreted signaling factor, Sonic hedgehog (Shh), has a crucial role in the generation of ventral cell types along the entire rostrocaudal axis of the neural…”
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9
Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish
Published in Development (Cambridge) (01-12-1995)“…In zebrafish, individual primary motoneurons can be uniquely identified by their characteristic cell body positions and axonal projection patterns. The fate of…”
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10
The effect of antimicrobial therapy on periimplantitis lesions. An experimental study in the dog
Published in Clinical oral implants research (01-12-1996)“…The objective of the present study was to evaluate the effect of systemic antibiotics and local debridement in the treatment of experimentally induced…”
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11
The Rat Extracellular Superoxide Dismutase Dimer is Converted to a Tetramer by the Exchange of a Single Amino Acid
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-1996)“…Extracellular superoxide dismutase (EC-SOD) is a secreted Cu and Zn-containing glycoprotein. While EC-SOD from most mammals is tetrameric and has a high…”
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12
Heparin-affinity patterns and composition of extracellular superoxide dismutase in human plasma and tissues
Published in Biochemical journal (15-09-1993)“…The tetrameric extracellular superoxide dismutase (EC-SOD) in human tissues and plasma has previously been found to be heterogenous with regard to heparin…”
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13
Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube
Published in The International journal of developmental biology (01-10-1995)“…The vertebrate hedgehog-related gene, sonic hedgehog, is expressed in ventral domains along the entire rostrocaudal length of the neural tube, including the…”
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14
The heparin-binding domain of extracellular superoxide dismutase C and formation of variants with reduced heparin affinity
Published in The Journal of biological chemistry (05-09-1992)“…A fundamental property of the secretory tetrameric extracellular superoxide dismutase (EC-SOD) is its affinity for heparin and analogues, in vivo, mediating…”
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15
The insulin gene promoter. A simplified nomenclature
Published in Diabetes (New York, N.Y.) (01-08-1995)“…The tools of molecular biology have rapidly expanded our knowledge of how β-cells regulate insulin gene expression. As this work has progressed in parallel in…”
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16
IPF1, a homeodomain protein with a dual function in pancreas development
Published in The International journal of developmental biology (01-10-1995)“…Insulin promoter factor 1 (IPF1), is a homeodomain protein which, in the adult mouse pancreas, is selectively expressed in beta-cells, and which binds to, and…”
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17
Isolation and Sequence of Complementary DNA Encoding Human Extracellular Superoxide Dismutase
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1987)“…A complementary DNA (cDNA) clone from a human placenta cDNA library encoding extracellular superoxide dismutase (EC-SOD; superoxide:superoxide oxidoreductase,…”
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18
The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-1992)“…Many eukaryotic genes are regulated by cAMP through a conserved cAMP response element (CRE). Here we show that, in the pancreatic islet cell line Tu6, a…”
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19
A Mutational Analysis of the Insulin Gene Transcription Control Region: Expression in Beta Cells is Dependent on Two Related Sequences within the Enhancer
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1987)“…Cell-specific expression of the insulin gene is controlled by cis-acting DNA sequences located within ≈ 350 base pairs of the 5′ flanking DNA immediately…”
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20
Increased ozone-induced airway neutrophilic inflammation in extracellular-superoxide dismutase null mice
Published in Respiratory medicine (01-04-2002)“…Extracellular-superoxide dismutase (EC-SOD) exists primarily in the tissue interstitium and the lung contains particularly large amounts of the enzyme. To…”
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