Search Results - "EDER, Matthias"

[177Lu]Lu-PSMA-617 (PluvictoTM): The First FDA-Approved Radiotherapeutical for Treatment of Prostate Cancer by Hennrich, Ute, Eder, Matthias

“…In March 2022, [177Lu]Lu-PSMA-617 (PluvictoTM) was approved by the FDA for the treatment of prostate cancer patients. Until now, the approval has been limited…”
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A Simple Expression for the Screening of Excitonic Couplings between Chlorophylls as Inferred for Photosystem I Trimers by Eder, Matthias, Renger, Thomas

“…The Coulomb coupling between transition densities of the pigments in photosynthetic pigment-protein complexes, termed excitonic coupling, is a key factor for…”
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New Strategies in Prostate Cancer: Prostate-Specific Membrane Antigen (PSMA) Ligands for Diagnosis and Therapy by Haberkorn, Uwe, Eder, Matthias, Kopka, Klaus, Babich, John W, Eisenhut, Michael

“…Key issues for prostate cancer patients are the detection of recurrent disease and the treatment of metastasized cancer. Early detection is a major challenge…”
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The Role of m6A/m-RNA Methylation in Stress Response Regulation by Engel, Mareen, Eggert, Carola, Kaplick, Paul M., Eder, Matthias, Röh, Simone, Tietze, Lisa, Namendorf, Christian, Arloth, Janine, Weber, Peter, Rex-Haffner, Monika, Geula, Shay, Jakovcevski, Mira, Hanna, Jacob H., Leshkowitz, Dena, Uhr, Manfred, Wotjak, Carsten T., Schmidt, Mathias V., Deussing, Jan M., Binder, Elisabeth B., Chen, Alon

“…N6-methyladenosine (m6A) and N6,2′-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of…”
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The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions by Afshar-Oromieh, Ali, Hetzheim, Henrik, Kratochwil, Clemens, Benesova, Martina, Eder, Matthias, Neels, Oliver C, Eisenhut, Michael, Kübler, Wolfgang, Holland-Letz, Tim, Giesel, Frederik L, Mier, Walter, Kopka, Klaus, Haberkorn, Uwe

“…PET imaging with the prostate-specific membrane antigen (PSMA)-targeted radioligand (68)Ga-PSMA-11 is regarded as a significant step forward in the diagnosis…”
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Incidence, risk factors and healthcare costs of central line-associated nosocomial bloodstream infections in hematologic and oncologic patients by Baier, Claas, Linke, Lena, Eder, Matthias, Schwab, Frank, Chaberny, Iris Freya, Vonberg, Ralf-Peter, Ebadi, Ella

“…Non-implanted central vascular catheters (CVC) are frequently required for therapy in hospitalized patients with hematological malignancies or solid tumors…”
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Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML by Thol, Felicitas, Gabdoulline, Razif, Liebich, Alessandro, Klement, Piroska, Schiller, Johannes, Kandziora, Christian, Hambach, Lothar, Stadler, Michael, Koenecke, Christian, Flintrop, Madita, Pankratz, Mira, Wichmann, Martin, Neziri, Blerina, Büttner, Konstantin, Heida, Bennet, Klesse, Sabrina, Chaturvedi, Anuhar, Kloos, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Gaidzik, Verena I., Bullinger, Lars, Fiedler, Walter, Heim, Albert, Hamwi, Iyas, Eder, Matthias, Krauter, Jürgen, Schlenk, Richard F., Paschka, Peter, Döhner, Konstanze, Döhner, Hartmut, Ganser, Arnold, Heuser, Michael

“…Molecular measurable residual disease (MRD) assessment is not established in approximately 60% of acute myeloid leukemia (AML) patients because of the lack of…”
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Linker Modification Strategies To Control the Prostate-Specific Membrane Antigen (PSMA)-Targeting and Pharmacokinetic Properties of DOTA-Conjugated PSMA Inhibitors by Benešová, Martina, Bauder-Wüst, Ulrike, Schäfer, Martin, Klika, Karel D, Mier, Walter, Haberkorn, Uwe, Kopka, Klaus, Eder, Matthias

“…Since prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of prostate cancer (PCa), PSMA can be considered as a viable diagnostic…”
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Radiation dosimetry of 68Ga-PSMA-11 (HBED-CC) and preliminary evaluation of optimal imaging timing by Afshar-Oromieh, Ali, Hetzheim, Henrik, Kübler, Wolfgang, Kratochwil, Clemens, Giesel, Frederik L., Hope, Thomas A., Eder, Matthias, Eisenhut, Michael, Kopka, Klaus, Haberkorn, Uwe

“…Purpose The clinical introduction of 68 Ga-PSMA-11 (“HBED-CC”) ligand targeting the prostate-specific membrane antigen (PSMA) has been regarded as a…”
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Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years by Schmidt, Julius J, Lueck, Catherina, Ziesing, Stefan, Stoll, Matthias, Haller, Hermann, Gottlieb, Jens, Eder, Matthias, Welte, Tobias, Hoeper, Marius M, Scherag, André, David, Sascha

“…Despite modern intensive care with standardized strategies against acute respiratory distress syndrome (ARDS), Pneumocystis pneumonia (PcP) remains a…”
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QTL mapping of volatile compound production in Saccharomyces cerevisiae during alcoholic fermentation by Eder, Matthias, Sanchez, Isabelle, Brice, Claire, Camarasa, Carole, Legras, Jean-Luc, Dequin, Sylvie

“…The volatile metabolites produced by Saccharomyces cerevisiae during alcoholic fermentation, which are mainly esters, higher alcohols and organic acids, play a…”
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[68Ga]Ga-PSMA-11: The First FDA-Approved 68Ga-Radiopharmaceutical for PET Imaging of Prostate Cancer by Hennrich, Ute, Eder, Matthias

“…For the positron emission tomography (PET) imaging of prostate cancer, radiotracers targeting the prostate-specific membrane antigen (PSMA) are nowadays used…”
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Novel Preclinical and Radiopharmaceutical Aspects of [68Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer by Eder, Matthias, Neels, Oliver, Müller, Miriam, Bauder-Wüst, Ulrike, Remde, Yvonne, Schäfer, Martin, Hennrich, Ute, Eisenhut, Michael, Afshar-Oromieh, Ali, Haberkorn, Uwe, Kopka, Klaus

“…The detection of prostate cancer lesions by PET imaging of the prostate-specific membrane antigen (PSMA) has gained highest clinical impact during the last…”
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Cacna1c deficiency in forebrain glutamatergic neurons alters behavior and hippocampal plasticity in female mice by Loganathan, Srivaishnavi, Menegaz, Danusa, Delling, Jan Philipp, Eder, Matthias, Deussing, Jan M.

“…CACNA1C , coding for the α1 subunit of L-type voltage-gated calcium channel (LTCC) Ca v 1.2, has been associated with multiple psychiatric disorders. Clinical…”
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Gene Silencing by Small Regulatory RNAs in Mammalian Cells by Scherr, Michaela, Eder, Matthias

“…Since some years, activation of RNA interference (RNAi) has been developed into a widely used and powerful biological tool to functionally annotate genomes…”
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Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans by Gassen, Nils C, Hartmann, Jakob, Zschocke, Jürgen, Stepan, Jens, Hafner, Kathrin, Zellner, Andreas, Kirmeier, Thomas, Kollmannsberger, Lorenz, Wagner, Klaus V, Dedic, Nina, Balsevich, Georgia, Deussing, Jan M, Kloiber, Stefan, Lucae, Susanne, Holsboer, Florian, Eder, Matthias, Uhr, Manfred, Ising, Marcus, Schmidt, Mathias V, Rein, Theo

“…FK506 binding protein 51 (FKBP51) is an Hsp90 co-chaperone and regulator of the glucocorticoid receptor, and consequently of stress physiology. Clinical…”
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Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1 by Refojo, Damian, Schweizer, Martin, Kuehne, Claudia, Ehrenberg, Stefanie, Thoeringer, Christoph, Vogl, Annette M., Dedic, Nina, Schumacher, Marion, von Wolff, Gregor, Avrabos, Charilaos, Touma, Chadi, Engblom, David, Schütz, Günther, Nave, Klaus-Armin, Eder, Matthias, Wotjak, Carsten T., Sillaber, Inge, Holsboer, Florian, Wurst, Wolfgang, Deussing, Jan M.

“…The corticotropin-releasing hormone receptor 1 (CRHR1) critically controls behavioral adaptation to stress and is causally linked to emotional disorders. Using…”
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Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells by Venturini, Letizia, Battmer, Karin, Castoldi, Mirco, Schultheis, Beate, Hochhaus, Andreas, Muckenthaler, Martina U., Ganser, Arnold, Eder, Matthias, Scherr, Michaela

“…Aberrant micro RNA (miRNA) expression has been described in human malignancies including B-cell lymphomas. We here report BCR-ABL– and c-MYC–dependent…”
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Preclinical evaluation of a bispecific low-molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer by Eder, Matthias, Schäfer, Martin, Bauder-Wüst, Ulrike, Haberkorn, Uwe, Eisenhut, Michael, Kopka, Klaus

“…BACKGROUND It has recently been reported that metastases of prostate cancer usually show highly heterogeneous or partly lost prostate‐specific membrane antigen…”
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Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics by Shemesh, Yair, Forkosh, Oren, Mahn, Mathias, Anpilov, Sergey, Sztainberg, Yehezkel, Manashirov, Sharon, Shlapobersky, Tamar, Elliott, Evan, Tabouy, Laure, Ezra, Gili, Adler, Elaine S, Ben-Efraim, Yair J, Gil, Shosh, Kuperman, Yael, Haramati, Sharon, Dine, Julien, Eder, Matthias, Deussing, Jan M, Schneidman, Elad, Yizhar, Ofer, Chen, Alon

“…Social encounters are associated with varying degrees of stress. The authors show that modulation of stress system components in the medial amygdala alters…”
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