Search Results - "EDEN, R. J."

Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonist by Eden, R J, Costall, B, Domeney, A M, Gerrard, P A, Harvey, C A, Kelly, M E, Naylor, R J, Owen, D A, Wright, A

“…These studies characterise the pharmacology of ropinirole, a selective D-2 agonist. High-affinity human caudate binding revealed a Ki for D2 receptors of 2.9 x…”
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The role of DA1‐ and DA2‐receptors in the control of blood pressure by Hieble, JP, Eden, RJ, Mey, C.

“…1. Endogenous dopamine, acting through specific receptors on blood vessels, renal tubules and adrenal cortical cells, may play a role in the development and…”
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Cardiotoxicity of a new inotrope/vasodilator drug (SK&F 94120) in the dog by HARLEMAN, J. H, JOSEPH, E. C, EDEN, R. J, WALKER, T. F, MAJOR, I. R, LAMB, M. S

“…The cardiotoxicity and haemodynamic changes induced by IV administration of high doses of SK&F 94120, a novel positive inotrope/vasodilator, were studied in…”
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In vivo pharmacological studies with SK&F 94836, a potent inotrope/vasodilator with a sustained duration of action by Gristwood, R.W., Comer, M.B., Eden, R.J., Taylor, E.M., Turner, J.A., Wallduck, M., Owen, D.A.A.

“…1 SK&F 94836 (racemate) was studied in vivo for its cardiovascular properties in cats and dogs. 2 In anaesthetized cats and dogs SK&F 94836 administered…”
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Pharmacological studies with SK&F 94120, a novel positive inotropic agent with vasodilator activity by Gristwood, R W, Eden, R J, Owen, D A, Taylor, E M

“…The pharmacological properties of SK&F 94120 on the cardiovascular system have been studied in laboratory animal species. The compound was shown to have…”
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Pharmacological properties of the stereoisomers of prizidilol: their use in analysis of reflex tachycardia and blood pressure control in normotensive cats, rats, and dogs by Owen, D A, Eden, R J, Lamb, M S, Taylor, E M

“…Prizidilol, a combined vasodilator/beta-adrenoceptor antagonist, has two optical isomers. The pharmacological activities of these isomers have been established…”
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Theorems on High Energy Collisions of Elementary Particles by EDEN, R. J.

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Tolerance to peripheral, but not central, effects of ropinirole, a selective dopamine D2-like receptor agonist by Parker, S G, Raval, P, Yeulet, S, Eden, R J

“…Studies were conducted to determine possible development, and underlying mechanisms, of tolerance to the hypotensive effects of ropinirole…”
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Histamine H1-receptor antagonist activity assessed in conscious dogs by Wright, A, Raval, P, Eden, R J, Owen, D A

“…A simple, minimally invasive technique is described which allows assessment of histamine H1-receptor antagonist activity in conscious dogs. The technique is…”
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Canadian Colloquium on Theoretical Physics by EDEN, R. J

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Energy and Structural Change in the United Kingdom and Western Europe by Bending, R C, Cattell, R K, Eden, R J

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The Brueckner theory of nuclear structure by Eden, R. J.

“…The object of the Brueckner theory is to calculate the properties of atomic nuclei from a knowledge of the forces which act between nucleons in free space. The…”
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The quantum mechanics of non-holonomic systems by Eden, R. J.

“…Interactions of a non-holonomic type are fundamentally different from interactions which can be treated as part of the Hamiltonian of a system. They usually…”
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The Hamiltonian dynamics of non-holonomic systems by Eden, R. J.

“…A formalism is developed which makes it possible to express the equations of motion of a nonholonomic system in Poisson bracket form. The main difficulty which…”
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SK & F 95018, a vasodilator/beta-adrenoceptor antagonist by Swayne, G T, Owen, D A, Taylor, E M, Eden, R J, Slater, R A, Howson, W

“…The pharmacological properties of a novel vasodilator/beta-adrenoceptor antagonist, SK & F 95018 6-[4-[3-(3-[4-(2-Cyclopropylmethoxyethyl)phenoxy]-2-…”
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New Norepinephrine-Depleting Agents. β-Hydroxyphenethylguanidine and Related Compounds by Green, A. L, Fielden, R, Bartlett, D. C, Cozens, Mary J, Eden, R. J, Hills, D. W

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The effect of SK&F 95654, a novel phosphodiesterase inhibitor, on cardiovascular, respiratory and platelet function by Murray, Kenneth J., Eden, Roger J., Dolan, John S., Grimsditch, David C., Stutchbury, Catherine A., Patel, Bella, Knowles, Aileen, Worby, Angela, Lynham, James A., Coates, William J.

“…1 SK&F 95654 inhibited the guanosine 3′:5′‐cyclic monophosphate (cyclic GMP)‐inhibited phosphodiesterase (cGI‐PDE) with an IC50 value of 0.7 μm. The IC50…”
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Threshold behaviour in quantum field theory by Eden, R. J.

“…The elements of the S matrix are functions of the energies and momenta of a set of incident particles. For sufficiently high relative energies of the incident…”
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The analytic behaviour of Heisenberg’s S matrix by Eden, R. J.

“…The S matrix is considered for a system made up of an elementary particle being scattered on a fixed centre which has internal excited states. At threshold…”
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Autonomic and haemodynamic responses to SK & F 101468 (ropinirole), a DA2 agonist, in anaesthetised cats by Eden, R J, Wallduck, M S, Patel, B, Owen, D A

“…The haemodynamic and autonomic nervous system effects of the DA2 agonist, SK & F 101468, have been studied in anaesthetised cats. SK & F 101468 inhibited the…”
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