Search Results - "EDEN, O. B"

Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases by Kerr, B, Delrue, M-A, Sigaudy, S, Perveen, R, Marche, M, Burgelin, I, Stef, M, Tang, B, Eden, O B, O’Sullivan, J, De Sandre-Giovannoli, A, Reardon, W, Brewer, C, Bennett, C, Quarell, O, M’Cann, E, Donnai, D, Stewart, F, Hennekam, R, Cavé, H, Verloes, A, Philip, N, Lacombe, D, Levy, N, Arveiler, B, Black, G

“…Background: Costello syndrome (CS) is a rare multiple congenital abnormality syndrome, associated with failure to thrive and developmental delay. One of the…”
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The contrasting age-incidence patterns of bone tumours in teenagers and young adults: Implications for aetiology by Arora, Ramandeep S., Alston, Robert D., Eden, Tim O.B., Geraci, Marco, Birch, Jillian M.

“…Bone tumours comprise 0.2% of cancers overall but 5.7% in 15–24 year olds. To explore the relationship with adolescence we have analysed age‐incidence patterns…”
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Treatment non-adherence in teenage and young adult patients with cancer by Kondryn, Helena J, PhD, Edmondson, Claire L, MBChB, Hill, Jonathan, Prof, Eden, Tim OB, Prof

“…Summary Adhering to treatment can be a significant issue for many patients diagnosed with chronic health conditions and this has been reported to be greater…”
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Prenatal origin of acute lymphoblastic leukaemia in children by Wiemels, JL, Cazzaniga, G, Daniotti, M, Eden, OB, Addison, GM, Masera, G, Saha, V, Biondi, A, Greaves, MF

“…There is little current insight into the natural history of childhood leukaemia or the timing of relevant mutational events. TEL-AML1 gene fusion due to…”
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Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements by PUI, C-H, CHESSELLS, J. M, HARHOTT, J, HARMS, D. O, HARRISON, C. J, HARRISON, P. L, HEEREMA, N, JANKA-SCHAUB, G, KAMPS, W, MASERA, G, PULLEN, J, RAIMONDI, S. C, CAMITTA, B, RICHARDS, S, RIEHM, H, SALLAN, S, SATHER, H, SHUSTER, J, SILVERMAN, L. B, VALSECCHI, M. G, VILMER, E, ZHOU, Y, GAYNON, P. S, BARUCHEL, A, SCHRAPPE, M, BIONDI, A, BOYETT, J. M, CARROLL, A, EDEN, O. B, EVANS, W. E, GADNER, H

“…To assess the clinical heterogeneity among patients with acute lymphoblastic leukemia (ALL) and various 11q23 abnormalities, we analyzed data on 497 infants,…”
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The development of evidence-based guidelines on mouth care for children, teenagers and young adults treated for cancer by Glenny, A.M, Gibson, F, Auld, E, Coulson, S, Clarkson, J.E, Craig, J.V, Eden, O.B, Khalid, T, Worthington, H.V, Pizer, B

“…Abstract The aim was to produce evidence-based guidelines on mouth care for children, teenagers and young adults receiving chemotherapy and/or radiotherapy…”
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Are reported increases in incidence of primary CNS tumours real? An analysis of longitudinal trends in England, 1979–2003 by Arora, Ramandeep S, Alston, Robert D, Eden, Tim O.B, Estlin, Edward J, Moran, Anthony, Geraci, Marco, Birch, Jillian M

“…Abstract Reported increases in the incidence of CNS tumours in the developed world in the 1970s to 1990s have been a cause for concern and debate. It still…”
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Comparative incidence patterns and trends of gonadal and extragonadal germ cell tumors in England, 1979 to 2003 by Arora, Ramandeep S., Alston, Robert D., Eden, Tim O. B., Geraci, Marco, Birch, Jillian M

“…BACKGROUND: It is believed that gonadal and extragonadal germ cell tumors (GCTs) arise from primordial germ cells and may have similar etiopathogenesis. Unlike…”
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Interventions for treating oral mucositis for patients with cancer receiving treatment by Clarkson, J E, Worthington, H V, Eden, O B

“…Treatment of cancer is increasingly effective but associated with short and long term side effects. Oral side effects, including oral mucositis (mouth…”
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Interventions for preventing oral candidiasis for patients with cancer receiving treatment by Clarkson, J E, Worthington, H V, Eden, O B

“…Treatment of cancer is increasingly more effective but is associated with short and long term side effects. Oral side effects remain a major source of illness…”
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The UK experience in treating relapsed childhood acute lymphoblastic leukaemia: a report on the Medical Research Council UKALLR1 study by LAWSON, S. E, HARRISON, G, RICHARDS, S, OAKHILL, A, STEVENS, R, EDEN, O. B, DARBYSHIRE, P. J

“…We have examined the toxicity and overall outcome of the Medical Research Council UKALL R1 protocol for 256 patients with relapsed childhood acute…”
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Growth hormone status in adults treated for acute lymphoblastic leukaemia in childhood by BRENNAN, B. M. D, RAHIM, A, MACKIE, E. M, EDEN, O. B, SHALET, S. M

“…OBJECTIVE Growth hormone status was assessed in a cohort of 32 (16 male) adults who had received cranial irradiation (XRT) in childhood as part of their…”
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Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997 by EDEN, O. B, HARRISON, G, RICHARDS, S, LILLEYMAN, J. S, BAILEY, C. C, CHESSELLS, J. M, HANN, I. M, HILL, F. G. H, GIBSON, B. E. S

“…Results of three consecutive completed UK trials (1980-1997) for childhood lymphoblastic leukaemia are presented. National accrual has progressively increased…”
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Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial by Mitchell, C. D., Richards, S. M., Kinsey, S. E., Lilleyman, J., Vora, A., Eden, T. O. B.

“…Summary Corticosteroids are an essential component of treatment for acute lymphoblastic leukaemia (ALL). Prednisolone is the most commonly used steroid,…”
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Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study by FEAR, N. T, ROMAN, E, ANSELL, P, SIMPSON, J, DAY, N, EDEN, O. B

“…The relationship between neonatal vitamin K received by the intramuscular (i.m.) route and the development of leukaemia or other cancers was investigated as…”
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An infectious aetiology for childhood acute leukaemia: a review of the evidence by McNally, Richard J. Q., Eden, Tim O. B.

“…Summary There are three current hypotheses concerning infectious mechanisms in the aetiology of childhood leukaemia: exposure in utero or around the time of…”
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An infectious aetiology for childhood brain tumours? Evidence from space-time clustering and seasonality analyses by MCNALLY, R. J. Q, CAIRNS, D. P, EDEN, O. B, ALEXANDER, F. E, TAYLOR, G. M, KELSEY, A. M, BIRCH, J. M

“…To investigate whether infections or other environmental exposures may be involved in the aetiology of childhood central nervous system tumours, we have…”
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Incidence and survival of childhood Langerhans cell histiocytosis in Northwest England from 1954 to 1998 by Alston, R.D., Tatevossian, R.G., McNally, R.J.Q., Kelsey, A., Birch, J.M., Eden, T.O.B.

“…Background Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of pathological Langerhans cells, for which the aetiology and pathogenesis…”
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Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21) by Moorman, Anthony V., Richards, Susan M., Robinson, Hazel M., Strefford, Jon C., Gibson, Brenda E.S., Kinsey, Sally E., Eden, Tim O.B., Vora, Ajay J., Mitchell, Christopher D., Harrison, Christine J.

“…Patients with acute lymphoblastic leukemia (ALL) and an intrachromosomal amplification of chromosome 21 (iAMP21) comprise a novel and distinct biological…”
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Benefit of intensified treatment for all children with acute lymphoblastic leukaemia : results from MRC UKALL XI and MRC ALL97 randomised trials by HANN, I, VORA, A, RICHARDS, S, HILL, F, GIBSON, B, LILLEYMAN, J, KINSEY, S, MITCHELL, C, EDEN, O. B

“…Treatment of children with acute lymphoblastic leukaemia (ALL) aims to cure all patients with as little toxicity as possible and, if possible, to restrict…”
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