Search Results - "ECKERT, Matti"

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders by GRABRUCKER, Stefanie, JANNETTI, Linda, KREUTZ, Michael R, EHRET, Günter, BOECKERS, Tobias M, GRABRUCKER, Andreas M, ECKERT, Matti, GAUB, Simone, CHHABRA, Resham, PFAENDER, Stefanie, MANGUS, Katharina, PARAMESHWAR PASHAM REDDY, RANKOVIC, Vladan, SCHMEISSER, Michael J

“…Proteins of the ProSAP/Shank family act as major organizing scaffolding elements within the postsynaptic density of excitatory synapses. Deletions, mutations…”
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The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation by Grabrucker, Stefanie, Proepper, Christian, Mangus, Katharina, Eckert, Matti, Chhabra, Resham, Schmeisser, Michael J., Boeckers, Tobias M., Grabrucker, Andreas M.

“…Recently, mutations in ProSAP2/Shank3 have been discovered as one of the genetic factors for schizophrenia (SCZ). Here, we show that the postsynaptic density…”
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Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2 by Sarowar, Tasnuva, Grabrucker, Stefanie, Föhr, Karl, Mangus, Katharina, Eckert, Matti, Bockmann, Juergen, Boeckers, Tobias M, Grabrucker, Andreas M

“…The majority of neurons within the central nervous system receive their excitatory inputs via small, actin-rich protrusions called dendritic spines. Spines can…”
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