Search Results - "ECKERT, ANNE"

Brain aging and neurodegeneration: from a mitochondrial point of view by Grimm, Amandine, Eckert, Anne

“…Aging is defined as a progressive time‐related accumulation of changes responsible for or at least involved in the increased susceptibility to disease and…”
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Insights into Disease-Associated Tau Impact on Mitochondria by Szabo, Leonora, Eckert, Anne, Grimm, Amandine

“…Abnormal tau protein aggregation in the brain is a hallmark of tauopathies, such as frontotemporal lobar degeneration and Alzheimer's disease. Substantial…”
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Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer’s disease by Grimm, Amandine, Friedland, Kristina, Eckert, Anne

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease that represents the most common form of dementia among the elderly. Despite the fact that…”
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Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence by Eckert, Anne, Grimm, Amandine, Agapouda, Anastasia, Lejri, Imane

“…Alzheimer’s disease (AD) is the most common form of dementia affecting people mainly in their sixth decade of life and at a higher age. It is an extensively…”
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Amyloid-Beta Interaction with Mitochondria by Pagani, Lucia, Eckert, Anne

“…Mitochondrial dysfunction is a hallmark of amyloid-beta(Aβ)-induced neuronal toxicity in Alzheimer's disease (AD). The recent emphasis on the intracellular…”
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Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects by Holze, Friederike, Vizeli, Patrick, Ley, Laura, Müller, Felix, Dolder, Patrick, Stocker, Melanie, Duthaler, Urs, Varghese, Nimmy, Eckert, Anne, Borgwardt, Stefan, Liechti, Matthias E

“…Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy. However, no modern studies have evaluated…”
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Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics by Schmitt, Karen, Grimm, Amandine, Dallmann, Robert, Oettinghaus, Bjoern, Restelli, Lisa Michelle, Witzig, Melissa, Ishihara, Naotada, Mihara, Katsuyoshi, Ripperger, Jürgen A., Albrecht, Urs, Frank, Stephan, Brown, Steven A., Eckert, Anne

“…Mitochondrial fission-fusion dynamics and mitochondrial bioenergetics, including oxidative phosphorylation and generation of ATP, are strongly…”
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Mitochondria, Estrogen and Female Brain Aging by Lejri, Imane, Grimm, Amandine, Eckert, Anne

“…Mitochondria play an essential role in the generation of steroid hormones including the female sex hormones. These hormones are, in turn, able to modulate…”
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Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway by Lejri, Imane, Grimm, Amandine, Eckert, Anne

“…Standardized Ginkgo biloba extract (GBE) has demonstrated efficacy in the cognitive functional neuropsychiatric symptoms of patients with Alzheimer's disease…”
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Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice by Rhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Dröse, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Götz, Jürgen, Eckert, Anne

“…Alzheimer's disease (AD) is characterized by amyloid-beta (Aβ)-containing plaques, neurofibrillary tangles, and neuron and synapse loss. Tangle formation has…”
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Tau physiology and pathomechanisms in frontotemporal lobar degeneration by Bodea, Liviu‐Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier, Götz, Jürgen

“…Frontotemporal lobar degeneration (FTLD) has been associated with toxic intracellular aggregates of hyperphosphorylated tau (FTLD‐tau). Moreover, genetic…”
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Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein by Fairley, Lauren H, Lejri, Imane, Grimm, Amandine, Eckert, Anne

“…Abnormal tau build-up is a hallmark of Alzheimer's disease (AD) and more than 20 other serious neurodegenerative diseases. Mitochondria are paramount…”
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Interplay between stress, sleep, and BDNF in a high-risk sample of young adults by Varghese, Nimmy, Buergin, David, Boonmann, Cyril, Stadler, Christina, Schmid, Marc, Eckert, Anne, Unternaehrer, Eva

“…Children in institutional care have a high risk to experience childhood adversities (CAs), with consequences for physical and mental well-being. The long-term…”
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Dietary Mitophagy Enhancer: A Strategy for Healthy Brain Aging? by Varghese, Nimmy, Werner, Selina, Grimm, Amandine, Eckert, Anne

“…Recently, nutritional interventions have received attention as promising approaches to promote human health during a lifespan. The Mediterranean and Okinawan…”
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The interplay of stress and sleep impacts BDNF level by Giese, Maria, Unternaehrer, Eva, Brand, Serge, Calabrese, Pasquale, Holsboer-Trachsler, Edith, Eckert, Anne

“…Sleep plays a pivotal role in normal biological functions. Sleep loss results in higher stress vulnerability and is often found in mental disorders. There is…”
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Verbal and physical client aggression – A longitudinal analysis of professional caregivers’ psychophysiological stress response and burnout by Kind, Nina, Eckert, Anne, Steinlin, Célia, Fegert, Jörg M., Schmid, Marc

“…•Exposure to client aggression may increase the risk of work-related burnout.•Experiencing verbal and physical aggression could be linked to high hair…”
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Mitochondria Transfer in Brain Injury and Disease by Fairley, Lauren H, Grimm, Amandine, Eckert, Anne

“…Intercellular mitochondria transfer is a novel form of cell signalling in which whole mitochondria are transferred between cells in order to enhance cellular…”
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Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin by Holze, Friederike, Avedisian, Isidora, Varghese, Nimmy, Eckert, Anne, Liechti, Matthias E.

“…The psychedelic lysergic acid diethylamide (LSD) has experienced a revival in research, including clinical trials that evaluate LSD-assisted psychotherapy. LSD…”
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Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21 by Restelli, Lisa Michelle, Oettinghaus, Björn, Halliday, Mark, Agca, Cavit, Licci, Maria, Sironi, Lara, Savoia, Claudia, Hench, Jürgen, Tolnay, Markus, Neutzner, Albert, Schmidt, Alexander, Eckert, Anne, Mallucci, Giovanna, Scorrano, Luca, Frank, Stephan

“…Stress adaptation is essential for neuronal health. While the fundamental role of mitochondria in neuronal development has been demonstrated, it is still not…”
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Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex by Kuhn, Marion, Wolf, Elias, Maier, Jonathan G., Mainberger, Florian, Feige, Bernd, Schmid, Hanna, Bürklin, Jan, Maywald, Sarah, Mall, Volker, Jung, Nikolai H., Reis, Janine, Spiegelhalder, Kai, Klöppel, Stefan, Sterr, Annette, Eckert, Anne, Riemann, Dieter, Normann, Claus, Nissen, Christoph

“…Sleep is ubiquitous in animals and humans, but its function remains to be further determined. The synaptic homeostasis hypothesis of sleep–wake regulation…”
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