Search Results - "ECKEL, ROBERT H."

Treatment of Obesity by Wolfe, Bruce M, Kvach, Elizaveta, Eckel, Robert H

“…This review focuses on the mechanisms underlying, and indications for, bariatric surgery in the reduction of cardiovascular disease (CVD), as well as other…”
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Pathogenesis of Lipid Disorders in Insulin Resistance: a Brief Review by Bjornstad, Petter, Eckel, Robert H.

“…Purpose of review Insulin resistance (IR) is recognized to play an important role in the pathogenesis of dyslipidemia. This review summarizes the complex…”
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Lipoprotein lipase: from gene to obesity by Wang, Hong, Eckel, Robert H

“…Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues, including adipose tissue, cardiac and skeletal muscle, islets, and macrophages…”
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Sex differences in lipid and lipoprotein metabolism by Palmisano, Brian T., Zhu, Lin, Eckel, Robert H., Stafford, John M.

“…Endogenous sex hormones are important for metabolic health in men and women. Before menopause, women are protected from atherosclerotic cardiovascular disease…”
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Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity by Ross, Robert, Neeland, Ian J., Yamashita, Shizuya, Shai, Iris, Seidell, Jaap, Magni, Paolo, Santos, Raul D., Arsenault, Benoit, Cuevas, Ada, Hu, Frank B., Griffin, Bruce A., Zambon, Alberto, Barter, Philip, Fruchart, Jean-Charles, Eckel, Robert H., Matsuzawa, Yuji, Després, Jean-Pierre

“…Despite decades of unequivocal evidence that waist circumference provides both independent and additive information to BMI for predicting morbidity and risk of…”
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Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement by Neeland, Ian J, Ross, Robert, Després, Jean-Pierre, Matsuzawa, Yuji, Yamashita, Shizuya, Shai, Iris, Seidell, Jaap, Magni, Paolo, Santos, Raul D, Arsenault, Benoit, Cuevas, Ada, Hu, Frank B, Griffin, Bruce, Zambon, Alberto, Barter, Philip, Fruchart, Jean-Charles, Eckel, Robert H

“…Findings from epidemiological studies over the past 30 years have shown that visceral adipose tissue, accurately measured by CT or MRI, is an independent risk…”
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Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain by Markwald, Rachel R., Melanson, Edward L., Smith, Mark R., Higgins, Janine, Perreault, Leigh, Eckel, Robert H., Wright, Kenneth P.

“…Insufficient sleep is associated with obesity, yet little is known about how repeated nights of insufficient sleep influence energy expenditure and balance. We…”
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Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism by Bruce, Kimberley D, Zsombok, Andrea, Eckel, Robert H

“…Metabolic disorders, particularly aberrations in lipid homeostasis, such as obesity, type 2 diabetes mellitus, and hypertriglyceridemia often manifest together…”
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Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis by Skyler, Jay S, Bakris, George L, Bonifacio, Ezio, Darsow, Tamara, Eckel, Robert H, Groop, Leif, Groop, Per-Henrik, Handelsman, Yehuda, Insel, Richard A, Mathieu, Chantal, McElvaine, Allison T, Palmer, Jerry P, Pugliese, Alberto, Schatz, Desmond A, Sosenko, Jay M, Wilding, John P H, Ratner, Robert E

“…The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened…”
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Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity by Eckel, Robert H., Depner, Christopher M., Perreault, Leigh, Markwald, Rachel R., Smith, Mark R., McHill, Andrew W., Higgins, Janine, Melanson, Edward L., Wright, Kenneth P.

“…Short sleep duration and circadian misalignment are hypothesized to causally contribute to health problems including obesity, diabetes, metabolic syndrome,…”
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Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep by Depner, Christopher M., Melanson, Edward L., Eckel, Robert H., Snell-Bergeon, Janet K., Perreault, Leigh, Bergman, Bryan C., Higgins, Janine A., Guerin, Molly K., Stothard, Ellen R., Morton, Sarah J., Wright, Kenneth P.

“…People commonly increase sleep duration on the weekend to recover from sleep loss incurred during the workweek. Whether ad libitum weekend recovery sleep…”
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Preparing for the NASH Epidemic: A Call to Action by Kanwal, Fasiha, Shubrook, Jay H., Younossi, Zobair, Natarajan, Yamini, Bugianesi, Elisabetta, Rinella, Mary E., Harrison, Stephen A., Mantzoros, Christos, Pfotenhauer, Kim, Klein, Samuel, Eckel, Robert H., Kruger, Davida, El-Serag, Hashem, Cusi, Kenneth

“…Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common conditions with a rising burden. Yet there are significant…”
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Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways by Goldberg, Ira J., Eckel, Robert H., Abumrad, Nada A.

“…Cells obtain FAs either from LPL-catalyzed hydrolysis of lipoprotein triglyceride or from unesterified FFAs associated with albumin. LPL also influences uptake…”
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Approach to the Patient Who Is Intolerant of Statin Therapy by Eckel, Robert H.

“…Myopathy occurs in approximately 10% of statin-treated patients and is most commonly manifested by myalgias with or without plasma creatine kinase (CK)…”
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Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk by D Bruce, Kimberley, Tang, Maoping, Reigan, Philip, H Eckel, Robert

“…Lipoprotein lipase (LPL) is a key enzyme in lipid and lipoprotein metabolism. The canonical role of LPL involves the hydrolysis of triglyceride-rich…”
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Lipid catabolism via CPT1 as a therapeutic target for prostate cancer by Schlaepfer, Isabel R, Rider, Leah, Rodrigues, Lindsey Ulkus, Gijón, Miguel A, Pac, Colton T, Romero, Lina, Cimic, Adela, Sirintrapun, S Joseph, Glodé, L Michael, Eckel, Robert H, Cramer, Scott D

“…Prostate cancer is the most commonly diagnosed malignancy among Western men and accounts for the second leading cause of cancer-related deaths. Prostate cancer…”
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National Trends in Use of Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists by Cardiologists and Other Specialties, 2015 to 2020 by Adhikari, Rishav, Jha, Kunal, Dardari, Zeina, Heyward, James, Blumenthal, Roger S, Eckel, Robert H, Alexander, G Caleb, Blaha, Michael J

“…Background Sodium-glucose cotransporter-2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) mitigate cardiovascular risk in…”
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Pharmacological treatment and therapeutic perspectives of metabolic syndrome by Lim, Soo, Eckel, Robert H.

“…Metabolic syndrome is a disorder based on insulin resistance. Metabolic syndrome is diagnosed by a co-occurrence of three out of five of the following medical…”
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Lipoprotein(a) reductions from PCSK9 inhibition and major adverse cardiovascular events: Pooled analysis of alirocumab phase 3 trials by Ray, Kausik K., Vallejo-Vaz, Antonio J., Ginsberg, Henry N., Davidson, Michael H., Louie, Michael J., Bujas-Bobanovic, Maja, Minini, Pascal, Eckel, Robert H., Cannon, Christopher P.

“…Elevated lipoprotein(a) [Lp(a)] levels are considered a causal factor for cardiovascular disease. In phase 3 ODYSSEY trials, alirocumab reduced levels of…”
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Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans by Jung, Christopher M., Melanson, Edward L., Frydendall, Emily J., Perreault, Leigh, Eckel, Robert H., Wright, Kenneth P.

“…Non‐technical summary One of the proposed functions of sleep is to conserve energy. We determined the amount of energy conserved by sleep in humans, how much…”
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