Search Results - "ECHTENACHER, Bernd"

The Putative α-1,2-Mannosyltransferase AfMnt1 of the Opportunistic Fungal Pathogen Aspergillus fumigatus Is Required for Cell Wall Stability and Full Virulence by Wagener, Johannes, Echtenacher, Bernd, Rohde, Manfred, Kotz, Andrea, Krappmann, Sven, Heesemann, Jürgen, Ebel, Frank

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Genetic variation determines mast cell functions in experimental asthma by Becker, Marc, Reuter, Sebastian, Friedrich, Pamela, Doener, Fatma, Michel, Anastasija, Bopp, Tobias, Klein, Matthias, Schmitt, Edgar, Schild, Hansjörg, Radsak, Markus P, Echtenacher, Bernd, Taube, Christian, Stassen, Michael

“…Mast cell-deficient mice are a key for investigating the function of mast cells in health and disease. Allergic airway disease induced as a Th2-type immune…”
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Protection from septic shock by neutralization of macrophage migration inhibitory factor by Calandra, Thierry, Echtenacher, Bernd, Roy, Didier Le, Pugin, Jérôme, Metz, Christine N, Hültner, Lothar, Heumann, Didier, Männel, Daniela, Bucala, Richard, Glauser, Michel P

“…Identification of new therapeutic targets for the management of septic shock remains imperative as all investigational therapies, including anti-tumor necrosis…”
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Approaching the secrets of N-glycosylation in Aspergillus fumigatus: characterization of the AfOch1 protein by Kotz, Andrea, Wagener, Johannes, Engel, Jakob, Routier, Françoise H, Echtenacher, Bernd, Jacobsen, Ilse, Heesemann, Jürgen, Ebel, Frank

“…The mannosyltransferase Och1 is the key enzyme for synthesis of elaborated protein N-glycans in yeast. In filamentous fungi genes implicated in outer chain…”
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Studies on galactofuranose-containing glycostructures of the pathogenic mold Aspergillus fumigatus by Heesemann, Leonie, Kotz, Andrea, Echtenacher, Bernd, Broniszewska, Marzena, Routier, Françoise, Hoffmann, Petra, Ebel, Frank

“…Abstract Galactofuranose is a hexose that is exclusively found in microbes and in particular in certain pathogenic species. In the mold Aspergillus fumigatus ,…”
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Critical protective role of mast cells in a model of acute septic peritonitis by Echtenacher, Bernd, Männel, Daniela N, Hültner, Lothar

“…Mast cells play a detrimental role in IgE-dependent allergic reactions. In contrast, a protective function for mast cells has been proposed on the basis of…”
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The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle by Benigni, F, Atsumi, T, Calandra, T, Metz, C, Echtenacher, B, Peng, T, Bucala, R

“…Severe infection or tissue invasion can provoke a catabolic response, leading to severe metabolic derangement, cachexia, and even death. Macrophage migration…”
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The mitA gene of Aspergillus fumigatus is required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity by Kotz, Andrea, Wagener, Johannes, Engel, Jakob, Routier, Françoise, Echtenacher, Bernd, Pich, Andreas, Rohde, Manfred, Hoffmann, Petra, Heesemann, Jürgen, Ebel, Frank

“…GDP-mannose:inositol-phosphorylceramide (MIPC)-derived glycosphingolipids are important pathogen-associated molecular patterns (PAMP) of Candida albicans and…”
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Tumor Necrosis Factor-Dependent Adhesions as a Major Protective Mechanism Early in Septic Peritonitis in Mice by ECHTENACHER, Bernd, WEIGL, Karin, LEHN, Norbert, MÄNNEL, Daniela N

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The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cells by Maurer, M, Echtenacher, B, Hültner, L, Kollias, G, Männel, D N, Langley, K E, Galli, S J

“…Mast cells are thought to contribute significantly to the pathology and mortality associated with anaphylaxis and other allergic disorders. However, studies…”
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Differences in Innate Defense Mechanisms in Endotoxemia and Polymicrobial Septic Peritonitis by ECHTENACHER, Bernd, FREUDENBERG, Marina A, JACK, Robert S, MÄNNEL, Daniela N

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Divergence of Protection Induced by Bacterial Products and Sepsis-Induced Immune Suppression by Sterns, Theo, Pollak, Nils, Echtenacher, Bernd, Männel, Daniela N

“…Susceptibility to bacterial infections after a primary immune stimulation differs drastically depending on the presensitization of the innate immune system. To…”
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Involvement of the Lectin Pathway of Complement Activation in Antimicrobial Immune Defense during Experimental Septic Peritonitis by WINDBICHLER, Michaela, ECHTENACHER, Bernd, HEHLGANS, Thomas, JENSENIUS, Jens C, SCHWAEBLE, Wilhelm, MÄNNEL, Daniela N

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Acute Systemic Reaction and Lung Alterations Induced by an Antiplatelet Integrin gpIIb/IIIa Antibody in Mice by Nieswandt, Bernhard, Echtenacher, Bernd, Wachs, Frank-Peter, Schröder, Josef, Gessner, J. Engelbert, Schmidt, Reinhold E., Grau, Georges E., Männel, Daniela N.

“…Shock is frequently accompanied by thrombocytopenia. To investigate the pathogenic role of platelets in shock, we examined the in vivo effects of monoclonal…”
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Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice by NIESWANDT, B, ECHTENACHER, B, WACHS, F.-P, SCHRÖDER, J, GESSNER, J. E, SCHMIDT, R. E, GRAU, G. E, MÄNNEL, D. N

“…Shock is frequently accompanied by thrombocytopenia. To investigate the pathogenic role of platelets in shock, we examined the in vivo effects of monoclonal…”
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Woronin bodies, their impact on stress resistance and virulence of the pathogenic mould Aspergillus fumigatus and their anchoring at the septal pore of filamentous Ascomycota by Beck, Julia, Echtenacher, Bernd, Ebel, Frank

“…Summary Hyphae of filamentous Ascomycota consist of compartments that are connected via septal pores. To avoid a dramatic loss of cellular content after…”
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BMP6-induced modulation of the tumor micro-milieu by Stieglitz, David, Lamm, Susanne, Braig, Simone, Feuerer, Lena, Kuphal, Silke, Dietrich, Peter, Arndt, Stephanie, Echtenacher, Bernd, Hellerbrand, Claus, Karrer, Sigrid, Bosserhoff, Anja-Katrin

“…Melanoma is the deadliest form of skin cancer with rising incidence, creating a significant health problem. We discovered increased expression of bone…”
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Investigations on the involvement of the lectin pathway of complement activation in anaphylaxis by Windbichler, Michaela, Echtenacher, Bernd, Takahashi, Kazue, Ezekowitz, R Alan B, Schwaeble, Wilhelm J, Jenseniuis, Jens C, Männel, Daniela N

“…Systemic anaphylaxis is the most severe form of immediate hypersensitivity reaction. The activation of the complement system occurs during anaphylactic shock…”
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Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy by Bittner, Sebastian, Ruhland, Brigitte, Hofmann, Veronika, Schmidleithner, Lisa, Schambeck, Kathrin, Pant, Asmita, Stüve, Philipp, Delacher, Michael, Echtenacher, Bernd, Edinger, Matthias, Hoffmann, Petra, Rehli, Michael, Gebhard, Claudia, Strieder, Nicholas, Hehlgans, Thomas, Feuerer, Markus

“…Engineered regulatory T cell (Treg cell) therapy is a promising strategy to treat patients suffering from inflammatory diseases, autoimmunity, and transplant…”
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ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression by Hoetzenecker, Wolfram, Echtenacher, Bernd, Guenova, Emmanuella, Hoetzenecker, Konrad, Woelbing, Florian, Brück, Jürgen, Teske, Anna, Valtcheva, Nadejda, Fuchs, Kerstin, Kneilling, Manfred, Park, Ji-Hyeon, Kim, Kyu-Han, Kim, Kyu-Won, Hoffmann, Petra, Krenn, Claus, Hai, Tsonwin, Ghoreschi, Kamran, Biedermann, Tilo, Röcken, Martin

“…Sepsis is associated with a hyperinduction of proinflammatory cytokines. ATF3, a transcription factor, is induced in macrophages under conditions of endotoxic…”
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