Search Results - "EBERHARDT, E"

Development of a 3-D confinement-dependent dilation model for brittle rocks; part 2, formulation and parameterization based on the Cartesian plastic strain increments ratios approach by Rahjoo, M., Eberhardt, E.

“…Experiences from deep mining have seen an increase in operational and safety challenges related to excessive rock mass bulking due to brittle fracturing and…”
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Numerical modelling of three-dimension stress rotation ahead of an advancing tunnel face by Eberhardt, E

“…As underground excavations and construction works progress into deeper and more complex geological environments, understanding the three-dimensional…”
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C-reactive protein as robust laboratory value associated with prognosis in patients with stage III non-small cell lung cancer (NSCLC) treated with definitive radiochemotherapy by Richlitzki, Cedric, Wiesweg, Marcel, Metzenmacher, Martin, Guberina, Nika, Pöttgen, Christoph, Hautzel, Hubertus, Eberhardt, Wilfried E. E., Darwiche, Kaid, Theegarten, Dirk, Aigner, Clemens, Bölükbas, Servet, Schuler, Martin, Stuschke, Martin, Guberina, Maja

“…To evaluate the prognostic value of biomarkers from peripheral blood obtained as routine laboratory assessment for overall survival in a cohort of stage III…”
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Prediction of malignant lymph nodes in NSCLC by machine-learning classifiers using EBUS-TBNA and PET/CT by Guberina, Maja, Herrmann, Ken, Pöttgen, Christoph, Guberina, Nika, Hautzel, Hubertus, Gauler, Thomas, Ploenes, Till, Umutlu, Lale, Wetter, Axel, Theegarten, Dirk, Aigner, Clemens, Eberhardt, Wilfried E. E., Metzenmacher, Martin, Wiesweg, Marcel, Schuler, Martin, Karpf-Wissel, Rüdiger, Santiago Garcia, Alina, Darwiche, Kaid, Stuschke, Martin

“…Accurate determination of lymph-node (LN) metastases is a prerequisite for high precision radiotherapy. The primary aim is to characterise the performance of…”
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EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study by Pirker, Robert, Prof, Pereira, Jose R, MD, von Pawel, Joachim, MD, Krzakowski, Maciej, Prof, Ramlau, Rodryg, MD, Park, Keunchil, Prof, de Marinis, Filippo, MD, Eberhardt, Wilfried EE, MD, Paz-Ares, Luis, MD, Störkel, Stephan, Prof, Schumacher, Karl-Maria, MD, von Heydebreck, Anja, PhD, Celik, Ilhan, Prof, O'Byrne, Kenneth J, Prof

“…Summary Background Findings from the phase 3 First-Line ErbituX in lung cancer (FLEX) study showed that the addition of cetuximab to first-line chemotherapy…”
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Numerical analysis of initiation and progressive failure in natural rock slopes—the 1991 Randa rockslide by Eberhardt, E., Stead, D., Coggan, J.S.

“…The 1991 Randa rockslide in the Swiss Alps involved several complex mechanisms relating to geological, mechanical and hydrological processes for which no clear…”
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Application of Data Analysis Techniques to Identify Rockburst Mechanisms, Triggers, and Contributing Factors in Cave Mining by Roy, J. M., Eberhardt, E., Bewick, R. P., Campbell, R.

“…Mass mining methods such as block and panel caving are more commonly being utilized to generate value from deep, low-grade ore deposits. In addition to mining…”
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Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer by Brahmer, Julie, Reckamp, Karen L, Baas, Paul, Crinò, Lucio, Eberhardt, Wilfried E.E, Poddubskaya, Elena, Antonia, Scott, Pluzanski, Adam, Vokes, Everett E, Holgado, Esther, Waterhouse, David, Ready, Neal, Gainor, Justin, Arén Frontera, Osvaldo, Havel, Libor, Steins, Martin, Garassino, Marina C, Aerts, Joachim G, Domine, Manuel, Paz-Ares, Luis, Reck, Martin, Baudelet, Christine, Harbison, Christopher T, Lestini, Brian, Spigel, David R

“…In a randomized study of second-line therapy, treatment with nivolumab, an anti–PD-1 antibody, resulted in responses in more people and in better overall…”
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Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro by Borchert, Sabrina, Wessolly, Michael, Schmeller, Jan, Mairinger, Elena, Kollmeier, Jens, Hager, Thomas, Mairinger, Thomas, Herold, Thomas, Christoph, Daniel C, Walter, Robert F H, Eberhardt, Wilfried E E, Plönes, Till, Wohlschlaeger, Jeremias, Aigner, Clemens, Schmid, Kurt Werner, Mairinger, Fabian D

“…Malignant pleural mesothelioma (MPM) is a tumour arising from pleural cavities with poor prognosis. Multimodality treatment with pemetrexed combined with…”
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Investigation of the influence of natural fractures and in situ stress on hydraulic fracture propagation using a distinct-element approach by Zangeneh, N, Eberhardt, E, Bustin, R.M

“…Hydraulic fracturing is the primary means for enhancing rock mass permeability and improving well productivity in tight reservoir rocks. Significant advances…”
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Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma by Borchert, Sabrina, Suckrau, Pia-Maria, Walter, Robert F. H., Wessolly, Michael, Mairinger, Elena, Steinborn, Julia, Hegedus, Balazs, Hager, Thomas, Herold, Thomas, Eberhardt, Wilfried E. E., Wohlschlaeger, Jeremias, Aigner, Clemens, Bankfalvi, Agnes, Schmid, Kurt Werner, Mairinger, Fabian D.

“…Malignant pleural mesothelioma (MPM) is a rare, but aggressive tumor with dismal prognosis. Platinum-based chemotherapy is regularly used as part of…”
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Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma by Gore, M E, Szczylik, C, Porta, C, Bracarda, S, Bjarnason, G A, Oudard, S, Lee, S-H, Haanen, J, Castellano, D, Vrdoljak, E, Schöffski, P, Mainwaring, P, Hawkins, R E, Crinò, L, Kim, T M, Carteni, G, Eberhardt, W E E, Zhang, K, Fly, K, Matczak, E, Lechuga, M J, Hariharan, S, Bukowski, R

“…Background: We report final results with extended follow-up from a global, expanded-access trial that pre-regulatory approval provided sunitinib to metastatic…”
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Kinematic behaviour and velocity characteristics of a complex deep-seated crystalline rockslide system in relation to its interaction with a dam reservoir by Zangerl, C., Eberhardt, E., Perzlmaier, S.

“…This paper presents the geometry, kinematics and temporal deformation characteristics of a deep-seated rockslide system, the “Hochmais–Atemkopf”, situated…”
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Development and application of a pseudo-3D pit slope displacement map derived from ground-based radar by Severin, J., Eberhardt, E., Leoni, L., Fortin, S.

“…Slope monitoring plays an important role in the risk management of large open pit slopes. Historically, displacement data derived from measuring geodetic…”
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Vorinostat in patients with advanced malignant pleural mesothelioma who have progressed on previous chemotherapy (VANTAGE-014): a phase 3, double-blind, randomised, placebo-controlled trial by Krug, Lee M, Dr, Kindler, Hedy L, Prof, Calvert, Hilary, MD, Manegold, Christian, Prof, Tsao, Anne S, MD, Fennell, Dean, Prof, Öhman, Ronny, MD, Plummer, Ruth, Prof, Eberhardt, Wilfried E E, MD, Fukuoka, Kazuya, MD, Gaafar, Rabab M, Prof, Lafitte, Jean-Jacques, Prof, Hillerdal, Gunnar, MD, Chu, Quincy, MD, Buikhuisen, Wieneke A, MD, Lubiniecki, Gregory M, MD, Sun, Xing, PhD, Smith, Margaret, BA, Baas, Paul, Prof

“…Summary Background Vorinostat is a histone deacetylase inhibitor that changes gene expression and protein activity. On the basis of the clinical benefit…”
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Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial by Herbst, Roy S, Prof, Sun, Yan, MD, Eberhardt, Wilfried EE, MD, Germonpré, Paul, MD, Saijo, Nagahiro, Prof, Zhou, Caicun, MD, Wang, Jie, MD, Li, Longyun, MD, Kabbinavar, Fairooz, MD, Ichinose, Yukito, MD, Qin, Shukui, MD, Zhang, Li, MD, Biesma, Bonne, MD, Heymach, John V, MD, Langmuir, Peter, MD, Kennedy, Sarah J, MSc, Tada, Hiroomi, MD, Johnson, Bruce E, Prof

“…Summary Background Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor (VEGFR), epidermal growth factor receptor (EGFR),…”
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Long-term survival of patients with central or > 7 cm T4 N0/1 M0 non-small-cell lung cancer treated with definitive concurrent radiochemotherapy in comparison to trimodality treatment by Guberina, Nika, Pöttgen, Christoph, Schuler, Martin, Guberina, Maja, Stamatis, Georgios, Plönes, Till, Metzenmacher, Martin, Theegarten, Dirk, Gauler, Thomas, Darwiche, Kaid, Aigner, Clemens, Eberhardt, Wilfried E E, Stuschke, Martin

“…BACKGROUND: To examine long-term-survival of cT4 cN0/1 cM0 non-small-cell lung carcinoma (NSCLC) patients undergoing definitive radiochemotherapy ( RTx/CTx) in…”
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Treatment decisions, clinical outcomes, and pharmacoeconomics in the treatment of patients with EGFR mutated stage III/IV NSCLC in Germany: an observational study by Schuette, Wolfgang, Schirmacher, Peter, Eberhardt, Wilfried E E, Dietel, Manfred, Zirrgiebel, Ute, Muehlenhoff, Lars, Thomas, Michael

“…We evaluated treatment decisions and outcomes in a cohort of predominately Caucasian patients with EGFR mutation-positive (EGFR Mut+) non-small-cell lung…”
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In Vivo Selection of Paromomycin and Miltefosine Resistance in Leishmania donovani and L. infantum in a Syrian Hamster Model by Hendrickx, S, Mondelaers, A, Eberhardt, E, Delputte, P, Cos, P, Maes, L

“…In 2002 and 2006, respectively, miltefosine (MIL) and paromomycin (PMM) were licensed in the Indian subcontinent for treatment of visceral leishmaniasis;…”
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Damage initiation and propagation in hard rock during tunnelling and the influence of near-face stress rotation by Diederichs, M.S, Kaiser, P.K, Eberhardt, E

“…One of the critical design problems involved in deep tunnelling in brittle rock with continuous excavation techniques, such as those utilizing tunnel boring…”
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