Search Results - "EASTHAM, J"

The evolution of chemotherapy for the treatment of prostate cancer by Quinn, D.I., Sandler, H.M., Horvath, L.G., Goldkorn, A., Eastham, J.A.

“…Chemotherapy has been explored as a treatment option for metastatic prostate cancer since the early 1980s. Docetaxel, a taxane chemotherapeutic, was approved…”
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An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies by Ye, X, Li, Y, Stawicki, S, Couto, S, Eastham-Anderson, J, Kallop, D, Weimer, R, Wu, Y, Pei, L

“…Axl is expressed in various types of cancer and is involved in multiple processes of tumorigenesis, including promoting tumor cell growth, migration, invasion,…”
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Keel bone fractures induce a depressive-like state in laying hens by Armstrong, E. A., Rufener, C., Toscano, M. J., Eastham, J. E., Guy, J. H., Sandilands, V., Boswell, T., Smulders, T. V.

“…In commercial flocks of laying hens, keel bone fractures (KBFs) are prevalent and associated with behavioural indicators of pain. However, whether their impact…”
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Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp by Mahdee, A., Eastham, J., Whitworth, J. M., Gillespie, J. I.

“…Aim To examine rat molar pulp innervation and identify complex cellular signalling systems involving nerve growth factor (NGF) and its p75 receptors (NGFR) at…”
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Selecting Patients with Favorable Risk, Grade Group 2 Prostate Cancer for Active Surveillance-Does Magnetic Resonance Imaging Have a Role? by Stonier, T, Tin, A L, Sjoberg, D D, Jibara, G, Vickers, A J, Fine, S, Eastham, J

“…The National Comprehensive Cancer Network® recommends that selected men with grade group 2 prostate cancer be considered for active surveillance. However,…”
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Midurethral Sling Is the Dominant Procedure for Female Stress Urinary Incontinence: Analysis of Case Logs From Certifying American Urologists by Chughtai, B.I, Elterman, D.S, Vertosick, E, Maschino, A, Eastham, J.A, Sandhu, J.S

“…Objective To investigate contemporary trends in the use of midurethral sling procedures for the surgical correction of female stress urinary incontinence over…”
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The very-high-risk prostate cancer: a contemporary update by Mano, R, Eastham, J, Yossepowitch, O

“…Background: Treatment of high-risk prostate cancer has evolved considerably over the past two decades, yet patients with very-high-risk features may still…”
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The expression of β3-adrenoceptor and muscarinic type 3 receptor immuno-reactivity in the major pelvic ganglion of the rat by Eastham, J., Stephenson, C., Korstanje, K., Gillespie, J. I.

“…Bladder afferent outflow, linked to sensation, plays a critical role in bladder pathology: abnormal outflow results in altered sensation, leading to increased…”
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Periprostatic adipose inflammation is associated with high-grade prostate cancer by Gucalp, A, Iyengar, N M, Zhou, X K, Giri, D D, Falcone, D J, Wang, H, Williams, S, Krasne, M D, Yaghnam, I, Kunzel, B, Morris, P G, Jones, L W, Pollak, M, Laudone, V P, Hudis, C A, Scher, H I, Scardino, P T, Eastham, J A, Dannenberg, A J

“…Background: Obesity, a cause of subclinical inflammation, is associated with increased risk of high-grade prostate cancer (PC) and poor outcomes. Whether…”
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Evidence for programmed odontoblast process retraction after dentine exposure in the rat incisor by Mahdee, A., Eastham, J., Whitworth, J.M., Gillespie, J.I.

“…•New observations on structural complexity of odontoblast processes.•Strong evidence of odontoblast process extension to DEJ in intact rat incisor.•Programmed…”
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Determining conventional and unconventional oil and gas well brines in natural samples I: Anion analysis with ion chromatography by Cantlay, Tetiana, Eastham, J. Lucas, Rutter, Jennifer, Bain, Daniel J., Dickson, Bruce C., Basu, Partha, Stolz, John F.

“…Unconventional natural gas extraction by hydraulic fracturing requires millions of gallons of water and generates flowback water, produced water and recycled…”
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Clinical effectiveness and cost-effectiveness of neonatal screening for inborn errors of metabolism using tandem mass spectrometry: a systematic review by Pandor, A, Eastham, J, Beverley, C, Chilcott, J, Paisley, S

“…OBJECTIVESTo evaluate the clinical and cost-effectiveness of tandem mass spectrometry (MS)-based neonatal screening for inborn errors of metabolism (IEM). DATA…”
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Androgen deprivation therapy and estrogen deficiency induced adverse effects in the treatment of prostate cancer by Freedland, S J, Eastham, J, Shore, N

“…Androgen deprivation therapy (ADT) is the standard of care for metastatic prostate cancer and is increasingly used to treat asymptomatic patients with…”
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Ki-67 and outcome in clinically localised prostate cancer: analysis of conservatively treated prostate cancer patients from the Trans-Atlantic Prostate Group study by Berney, D M, Gopalan, A, Kudahetti, S, Fisher, G, Ambroisine, L, Foster, C S, Reuter, V, Eastham, J, Moller, H, Kattan, M W, Gerald, W, Cooper, C, Scardino, P, Cuzick, J

“…Treatment decisions after diagnosis of clinically localised prostate cancer are difficult due to variability in tumour behaviour. We therefore examined one of…”
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A Preoperative Nomogram for Disease Recurrence Following Radical Prostatectomy for Prostate Cancer by Kattan, Michael W., Eastham, James A., Stapleton, Alan M. F., Wheeler, Thomas M., Scardino, Peter T.

“…Few published studies have combined clinical prognostic factors into risk profiles that can be used to predict the likelihood of recurrence or metastatic…”
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027 Is There a Relationship Between Phosphodiesterase Type 5 Inhibitors (PDE5i) and Prostate Cancer Biochemical Recurrence? by Jenkins, L., Eastham, J., Laudone, V., Scardino, P., Nelson, C., Mulhall, J.

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Long-term outcome among men with conservatively treated localised prostate cancer by CUZICK, J, FISHER, G, SCARDINO, P, KATTAN, M. W, BERNEY, D, OLIVER, T, FOSTER, C. S, MØLLER, H, REUTER, V, FEARN, P, EASTHAM, J

“…Optimal management of clinically localised prostate cancer presents unique challenges, because of its highly variable and often indolent natural history. There…”
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Complex cellular responses to tooth wear in rodent molar by Mahdee, A, Alhelal, A, Eastham, J, Whitworth, J, Gillespie, J.I

“…Highlights • In rodent model odontoblast processes extend to the outer dentine. • Complex arborisation are seen in the distal third of the odontoblast process…”
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An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality by Sullivan, J, Kopp, R, Stratton, K, Manschreck, C, Corines, M, Rau-Murthy, R, Hayes, J, Lincon, A, Ashraf, A, Thomas, T, Schrader, K, Gallagher, D, Hamilton, R, Scher, H, Lilja, H, Scardino, P, Eastham, J, Offit, K, Vijai, J, Klein, R J

“…Background: Genome-wide association studies have identified multiple single-nucleotide polymorphsims (SNPs) associated with prostate cancer (PCa). Although…”
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Salvage radical prostatectomy: Oncological outcomes from a large retrospective cohort study by Stonier, T.W., Tin, A., Jibara, G., Vickers, A., Fine, S., Vargas, H., Eastham, J.

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