Search Results - "E. Svensson, Jonas"
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Is serotonin transporter brain binding associated with the cortisol awakening response? An independent non-replication
Published in PloS one (31-08-2023)“…Background Serotonergic brain signaling is considered critical for an appropriate and dynamic adaptation to stress, seemingly through modulating limbic system…”
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Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain
Published in NeuroImage (Orlando, Fla.) (15-11-2019)“…[11C]raclopride is a well established PET tracer for the quantification of dopamine 2/3 receptors (D2/3R) in the striatum. Outside of the striatum the receptor…”
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Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: A PET study of within-subject correlations with [11C]FLB 457
Published in NeuroImage (Orlando, Fla.) (01-02-2021)“…Dopamine D2 receptors (D2-R) in extrastriatal brain regions are of high interest for research in a wide range of psychiatric and neurologic disorders…”
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4
Serotonin transporter availability increases in patients recovering from a depressive episode
Published in Translational psychiatry (10-05-2021)“…Molecular imaging studies have shown low cerebral concentration of serotonin transporter in patients suffering from depression, compared to healthy control…”
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In response to the letter “[11C]raclopride and extrastriatal binding to D2/3 receptors”
Published in NeuroImage (Orlando, Fla.) (15-02-2020)“…[...]Dr. Backes proposes that our findings of low or non-existing dopamine D2/3-receptor (D2/3R) occupancy of quetiapine in extrastriatal regions could be…”
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Evaluating the effect of rapamycin treatment in Alzheimer's disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol
Published in BMC neurology (04-04-2024)“…Rapamycin is an inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, and preclinical data demonstrate that it is a promising candidate for a…”
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In vivo correlation of serotonin transporter and 1B receptor availability in the human brain: a PET study
Published in Neuropsychopharmacology (New York, N.Y.) (01-09-2022)“…Abstract Synaptic serotonin levels in the brain are regulated by active transport into the bouton by the serotonin transporter, and by autoreceptors, such as…”
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Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages
Published in Human brain mapping (01-12-2023)“…Abstract Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to assess the biological age of the human brain. The difference…”
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Early stopping in clinical PET studies: How to reduce expense and exposure
Published in Journal of Cerebral Blood Flow & Metabolism (01-11-2021)“…Clinical positron emission tomography (PET) research is costly and entails exposing participants to radioactivity. Researchers should therefore aim to include…”
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Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET-derived features
Published in GeroScience (2024)“…To better assess the pathology of neurodegenerative disorders and the efficacy of neuroprotective interventions, it is necessary to develop biomarkers that can…”
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