Search Results - "E. Reyes"

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism by REYES-REYES, E. Merit, YUN TENG, BATES, Paula J

“…AS1411 is a first-in-class anticancer agent, currently in phase II clinical trials. It is a quadruplex-forming oligodeoxynucleotide that binds to nucleolin as…”
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Vivaria housing conditions expose sex differences in brain oxidation, microglial activation, and immune system states in aged hAPOE4 mice by Reyes-Reyes, E. M., Brown, J., Trial, M. D., Chinnasamy, D., Wiegand, J. P., Bradford, D., Brinton, R. D., Rodgers, K. E.

“…Apolipoprotein E ε4 allele (APOE4) is the predominant genetic risk factor for late-onset Alzheimer’s disease (AD). APOE4 mouse models have provided advances in…”
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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes by Reyes-Turcu, Francisca E, Ventii, Karen H, Wilkinson, Keith D

“…Deubiquitinating enzymes (DUBs) are proteases that process ubiquitin or ubiquitin-like gene products, reverse the modification of proteins by a single…”
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Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation by Reyes-Reyes, E. Merit, Šalipur, Francesca R., Shams, Mitra, Forsthoefel, Matthew K., Bates, Paula J.

“…AS1411 is a G-rich quadruplex-forming oligodeoxynucleotide that binds specifically to nucleolin, a protein found on the surface and in the cytoplasm of most…”
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Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells by Rodrigues, Patrick Fernandes, Alberti-Servera, Llucia, Eremin, Anna, Grajales-Reyes, Gary E., Ivanek, Robert, Tussiwand, Roxane

“…Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high amounts of type 1 interferons in response to viral infections…”
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Helicobacter pylori and Its Role in Gastric Cancer by Reyes, Victor E

“…Gastric cancer is a challenging public health concern worldwide and remains a leading cause of cancer-related mortality. The primary risk factor implicated in…”
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Involvement of Astrocytes in Alzheimer's Disease from a Neuroinflammatory and Oxidative Stress Perspective by González-Reyes, Rodrigo E, Nava-Mesa, Mauricio O, Vargas-Sánchez, Karina, Ariza-Salamanca, Daniel, Mora-Muñoz, Laura

“…Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in humans, but still no curative treatment has been developed. Although many…”
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Phytogenic Bioactive Compounds Shape Fish Mucosal Immunity by Firmino, Joana P., Galindo-Villegas, Jorge, Reyes-López, Felipe E., Gisbert, Enric

“…Aquaculture growth will unavoidably involve the implementation of innovative and sustainable production strategies, being functional feeds among the most…”
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Plasmon induced enhanced photocatalytic activity of gold loaded hydroxyapatite nanoparticles for methylene blue degradation under visible light by Mondal, Sudip, De Anda Reyes, Ma. E., Pal, Umapada

“…A facile surfactant free wet-precipitation process was employed to prepare hydroxyapatite (HAp) nanoparticles. Further, a microwave-assisted hydrothermal…”
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Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses by Tussiwand, Roxane, Everts, Bart, Grajales-Reyes, Gary E., Kretzer, Nicole M., Iwata, Arifumi, Bagaitkar, Juhi, Wu, Xiaodi, Wong, Rachel, Anderson, David A., Murphy, Theresa L., Pearce, Edward J., Murphy, Kenneth M.

“…The two major lineages of classical dendritic cells (cDCs) express and require either IRF8 or IRF4 transcription factors for their development and function…”
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CaMKII as a Therapeutic Target in Cardiovascular Disease by Reyes Gaido, Oscar E, Nkashama, Lubika J, Schole, Kate L, Wang, Qinchuan, Umapathi, Priya, Mesubi, Olurotimi O, Konstantinidis, Klitos, Luczak, Elizabeth D, Anderson, Mark E

“…CaMKII (the multifunctional Ca 2+ and calmodulin-dependent protein kinase II) is a highly validated signal for promoting a variety of common diseases,…”
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Electric Field- and Strain-Induced Rashba Effect in Hybrid Halide Perovskites by Leppert, Linn, Reyes-Lillo, Sebastian E, Neaton, Jeffrey B

“…Using first-principles density functional theory calculations, we show how Rashba-type energy band splitting in the hybrid organic–inorganic halide perovskites…”
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Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia by González-Reyes, Rodrigo E, Aliev, Gjumrakch, Ávila-Rodrigues, Marco, Barreto, George E

“…The use of the carbohydrate glucose as an energetic source is essential for an adequate function of the human body. The complex regulation of this molecule…”
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Restoration conundrum: between nostalgia and futuralgia, moving beyond the reference state by Reyes‐Aldana, Hugo E.

“…Returning to the pristine reference state is a primary goal of ecosystem restoration. However, the concept has faced criticism due to its unrealistic nature…”
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Transcriptional Control of Dendritic Cell Development by Murphy, Theresa L, Grajales-Reyes, Gary E, Wu, Xiaodi, Tussiwand, Roxane, Briseño, Carlos G, Iwata, Arifumi, Kretzer, Nicole M, Durai, Vivek, Murphy, Kenneth M

“…The dendritic cells (DCs) of the immune system function in innate and adaptive responses by directing activity of various effector cells rather than serving as…”
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Slow periodic activity in the longitudinal hippocampal slice can self‐propagate non‐synaptically by a mechanism consistent with ephaptic coupling by Chiang, Chia‐Chu, Shivacharan, Rajat S., Wei, Xile, Gonzalez‐Reyes, Luis E., Durand, Dominique M.

“…Key points Slow periodic activity can propagate with speeds around 0.1 m s−1 and be modulated by weak electric fields. Slow periodic activity in the…”
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Astrocytes as a Therapeutic Target in Alzheimer’s Disease–Comprehensive Review and Recent Developments by Rodríguez-Giraldo, Mateo, González-Reyes, Rodrigo E., Ramírez-Guerrero, Sofía, Bonilla-Trilleras, Carlos E., Guardo-Maya, Santiago, Nava-Mesa, Mauricio O.

“…Alzheimer’s disease (AD) is a frequent and disabling neurodegenerative disorder, in which astrocytes participate in several pathophysiological processes…”
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Organs-on-a-Chip Module: A Review from the Development and Applications Perspective by Sosa-Hernández, Juan Eduardo, Villalba-Rodríguez, Angel M, Romero-Castillo, Kenya D, Aguilar-Aguila-Isaías, Mauricio A, García-Reyes, Isaac E, Hernández-Antonio, Arturo, Ahmed, Ishtiaq, Sharma, Ashutosh, Parra-Saldívar, Roberto, Iqbal, Hafiz M N

“…In recent years, ever-increasing scientific knowledge and modern high-tech advancements in micro- and nano-scales fabrication technologies have impacted…”
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An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor by Reyes Gaido, Oscar E, Pavlaki, Nikoleta, Granger, Jonathan M, Mesubi, Olurotimi O, Liu, Bian, Lin, Brian L, Long, Alan, Walker, David, Mayourian, Joshua, Schole, Kate L, Terrillion, Chantelle E, Nkashama, Lubika J, Hulsurkar, Mohit M, Dorn, Lauren E, Ferrero, Kimberly M, Huganir, Richard L, Müller, Frank U, Wehrens, Xander H T, Liu, Jun O, Luczak, Elizabeth D, Bezzerides, Vassilios J, Anderson, Mark E

“…Ca /calmodulin-dependent protein kinase II (CaMKII) hyperactivity causes cardiac arrhythmias, a major source of morbidity and mortality worldwide. Despite…”
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Mucosal Immunity and B Cells in Teleosts: Effect of Vaccination and Stress by Parra, David, Reyes-Lopez, Felipe E, Tort, Lluis

“…Fish are subjected to several insults from the environment, which may endanger animal survival. Mucosal surfaces are the first line of defense against these…”
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