Search Results - "E. Montini"

Normalization of clonal diversity in gene therapy studies using shape constrained splines by Del Core, L., Cesana, D., Gallina, P., Secanechia, Y. N. Serina, Rudilosso, L., Montini, E., Wit, E. C., Calabria, A., Grzegorczyk, M. A.

“…Viral vectors are used to insert genetic material into semirandom genomic positions of hematopoietic stem cells which, after reinfusion into patients,…”
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Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy by Lattanzi, Annalisa, Salvagno, Camilla, Maderna, Claudio, Benedicenti, Fabrizio, Morena, Francesco, Kulik, Willem, Naldini, Luigi, Montini, Eugenio, Martino, Sabata, Gritti, Angela

“…Globoid cell leukodystrophy (GLD) is an inherited lysosomal storage disease caused by β-galactocerebrosidase (GALC) deficiency. Gene therapy (GT) should…”
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Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting by Cesani, M, Plati, T, Lorioli, L, Benedicenti, F, Redaelli, D, Dionisio, F, Biasco, L, Montini, E, Naldini, L, Biffi, A

“…Gene therapy using viral vectors that stably integrate into ex vivo cultured cells holds great promises for the treatment of monogenic diseases as well as…”
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Preclinical evaluation of donor-derived sleeping beauty modified CD19CAR+ lymphocytes for the treatment of acute lymphoblastic leukemia by Magnani, C, Mezzanotte, C, Cappuzzello, C, Benedicenti, F, Belotti, D, Cabiati, B, Bardini, M, Fazio, G, Cazzaniga, G, Cooper, L, Montini, E, Gaipa, G, Biondi, A, Biagi, E

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S106: LONG‐TERM FOLLOW‐UP OF BETA‐THALASSEMIA PATIENTS TREATED WITH HEMATOPOIETIC STEM CELL GENE THERAPY by Marktel, S, Scaramuzza, S, Giglio, F, Cicalese, M, Lidonnici, M, Rossi, C, Calbi, V, Masera, N, D'Angelo, E, Mirra, N, Origa, R, Tartaglione, I, Perrotta, S, Viarengo, G, Santoleri, L, Milani, R, Gattillo, S, Calabria, A, Montini, E, Graziadei, G, Naldini, L, Cappellini, M, Aiuti, A, Ciceri, F, Ferrari, G

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Control of acromegaly in more than 90% of patients after 10 years of pegvisomant therapy: an European referral centre real-life experience by Pirchio, R., Auriemma, R. S., Montini, M. E., Vergura, A., Pivonello, R., Colao, A.

“…Purpose Pegvisomant (PEG) efficaciously controls IGF-I excess in acromegaly and possesses a positive impact on glucose metabolism. Data on very prolonged PEG…”
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Cytokine-induced killer (CIK) cells engineered with chimeric antigen receptors (CARs) by sleeping beauty system by Magnani, C, Turazzi, N, Benedicenti, F, Tettamanti, S, Attianese, G. Giordano, Rossi, V, Montini, E, Cooper, L, Aiuti, A, Biondi, A, Biagi, E

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Argatroban for treatment of vein thrombosis complicating heparin-induced thrombocytopenia in haemodialyzed multiple myeloma: a case report by Pierfranceschi, M. Giorgi, Orlando, S, Chiesa, S, Barbera, M, Montini, E, Lombardi, F, Rossini, P, Bologna, G, Bacciu, S.A

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HIV-1 mediated insertional activation of STAT5B and BACH2 promotes the formation of a viral reservoir in T regulatory cells by D. Cesana, F. Santoni de Sio, L. Rudilosso, P. Gallina, A. Calabria, E. Bruzzesi, L. Passerini, S. Nozza, E. Vicenzi, G. Poli, S. Gregori, G. Tambussi, E. Montini

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HIV-1 mediated insertional activation of STAT5B promotes the formation of a viral reservoir in T regulatory cells by D. Cesana, F.R. Santoni de Sio, L. Rudilosso, P. Gallina, A. Calabria, L. Passerini, S. Nozza, E. Vicenzi, G. Poli, G. Tambussi, E. Montini

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Relevance of an academic GMP Pan-European vector infra-structure (PEVI) by Cohen-Haguenauer, O, Creff, N, Cruz, P, Tunc, C, Aïuti, A, Baum, C, Bosch, F, Blomberg, P, Cichutek, K, Collins, M, Danos, O, Dehaut, F, Federspiel, M, Galun, E, Garritsen, H, Hauser, H, Hildebrandt, M, Klatzmann, D, Merten, O W, Montini, E, O'Brien, T, Panet, A, Rasooly, L, Scherman, D, Schmidt, M, Schweitzer, M, Tiberghien, P, Vandendriessche, T, Ziehr, H, Ylä-Herttuala, S, von Kalle, C, Gahrton, G, Carrondo, M

“…In the past 5 years, European investigators have played a major role in the development of clinical gene therapy. The provision of substantial funds by some…”
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MID2, a Homologue of the Opitz Syndrome Gene MID1: Similarities in Subcellular Localization and Differences in Expression During Development by Buchner, Georg, Montini, Eugenio, Andolfi, Grazia, Quaderi, Nandita, Cainarca, Silvia, Messali, Silvia, Bassi, Maria Teresa, Ballabio, Andrea, Meroni, Germana, Franco, Brunella

“…The B-box family is an expanding new family of genes encoding proteins involved in diverse cellular functions such as developmental patterning and oncogenesis…”
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GMP production of anti-tumor cytotoxic T-cell lines for adoptive T-cell therapy in patients with solid neoplasia by Turin, I, Pedrazzoli, P, Tullio, C, Montini, E, Carmela La Grotteria, M, Schiavo, R, Perotti, C, Locatelli, F, Carretto, E, Maccario, R, Siena, S, Montagna, D

“…Background The adoptive transfer of ex vivo -induced tumor-specific T-cell lines provides a promising approach for cancer immunotherapy. We have demonstrated…”
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Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome by Aiuti, Alessandro, Biasco, Luca, Scaramuzza, Samantha, Ferrua, Francesca, Cicalese, Maria Pia, Baricordi, Cristina, Dionisio, Francesca, Calabria, Andrea, Giannelli, Stefania, Castiello, Maria Carmina, Bosticardo, Marita, Evangelio, Costanza, Assanelli, Andrea, Casiraghi, Miriam, Di Nunzio, Sara, Callegaro, Luciano, Benati, Claudia, Rizzardi, Paolo, Pellin, Danilo, Di Serio, Clelia, Schmidt, Manfred, Von Kalle, Christof, Gardner, Jason, Mehta, Nalini, Neduva, Victor, Dow, David J., Galy, Anne, Miniero, Roberto, Finocchi, Andrea, Metin, Ayse, Banerjee, Pinaki P., Orange, Jordan S., Galimberti, Stefania, Valsecchi, Maria Grazia, Biffi, Alessandra, Montini, Eugenio, Villa, Anna, Ciceri, Fabio, Roncarolo, Maria Grazia, Naldini, Luigi

“…Wiskott-Aldrich syndrome (WAS) is an inherited immunodeficiency caused by mutations in the gene encoding WASP, a protein regulating the cytoskeleton…”
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Characterisation of CTL directed towards non-inherited maternal alloantigens in human cord blood by MORETTA, A, LOCATELLI, F, MINGRAT, G, RONDINI, G, MONTAGNA, D, COMOLI, P, GANDOSSINI, S, MONTINI, E, LABIRIO, M, MACCARIO, R

“…Allogeneic cord blood transplantation (CBT), especially from unrelated donors, is being increasingly used for treating paediatric patients with both malignant…”
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Solitary breast metastases from a renal cell carcinoma by VASSALLI, Lucia, FERRARI, Vittorio D, SIMONCINI, Edda, RANGONI, Giovanni, MONTINI, Elisabetta, MARPICATI, Patrizia, MAMBRINI, Andrea, PAGANI, Mauro, AGAZZI, Cinzia, MARINI, Giovanni

“…A case of solitary and metachronous breast metastases from a renal cell carcinoma is described nine years after surgery. The review of the literature proves…”
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Vitamin A deficiency alters the bioelectric parameters and RNA content of rat gastric mucosa in vitro by Ventura, U, Ceriani, T, Montini, E, Romano, M, Ricci, V

“…The present study was aimed to investigate the mechanisms by which vitamin A plays a role in maintaining the efficiency of gastric mucosal barrier…”
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A Novel Human Serine-Threonine Phosphatase Related to the Drosophila Retinal Degeneration C (rdgC) Gene is Selectively Expressed in Sensory Neurons of Neural Crest Origin by Montini, E., Rugarli, E. I., Van de Vosse, E., Andolfi, G., Mariani, M., Puca, A. A., Consalez, G. G., den Dunnen, J. T., Ballabio, A., Franco, B.

“…Through our transcriptional mapping effort in the Xp22 region, we have isolated by exon trapping a new transcript highly homologous to the Drosophila retinal…”
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Liver-directed lentiviral gene therapy in a dog model of hemophilia B by Cantore, Alessio, Ranzani, Marco, Bartholomae, Cynthia C, Volpin, Monica, Valle, Patrizia Della, Sanvito, Francesca, Sergi, Lucia Sergi, Gallina, Pierangela, Benedicenti, Fabrizio, Bellinger, Dwight, Raymer, Robin, Merricks, Elizabeth, Bellintani, Francesca, Martin, Samia, Doglioni, Claudio, D'Angelo, Armando, VandenDriessche, Thierry, Chuah, Marinee K, Schmidt, Manfred, Nichols, Timothy, Montini, Eugenio, Naldini, Luigi

“…We investigated the efficacy of liver-directed gene therapy using lentiviral vectors in a large animal model of hemophilia B and evaluated the risk of…”
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AAV serotype 2 vectors preferentially integrate into active genes in mice by Kay, Mark A, Nakai, Hiroyuki, Montini, Eugenio, Fuess, Sally, Storm, Theresa A, Grompe, Markus

“…Recombinant adeno-associated virus serotype 2 (rAAV2) is a promising vector for gene therapy because it can achieve long-term stable transgene expression in…”
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