Search Results - "E. Goelz, Susan"

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity by Chung, Kyoung-Jin, Chatzigeorgiou, Antonios, Economopoulou, Matina, Garcia-Martin, Ruben, Alexaki, Vasileia I, Mitroulis, Ioannis, Nati, Marina, Gebler, Janine, Ziemssen, Tjalf, Goelz, Susan E, Phieler, Julia, Lim, Jong-Hyung, Karalis, Katia P, Papayannopoulou, Thalia, Blüher, Matthias, Hajishengallis, George, Chavakis, Triantafyllos

“…Obesity is commonly accompanied by inflammatory responses in white adipose tissues. Chavakis and colleagues identify a vicious cycle involving α 4 integrins…”
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Anti-JC virus antibodies: Implications for PML Risk Stratification by Gorelik, Leonid, Lerner, Michaela, Bixler, Sarah, Crossman, Mary, Schlain, Brian, Simon, Kenneth, Pace, Amy, Cheung, Anne, Chen, Ling Ling, Berman, Melissa, Zein, Fairuz, Wilson, Ewa, Yednock, Ted, Sandrock, Alfred, Goelz, Susan E., Subramanyam, Meena

“…Objective A study was undertaken to establish an enzyme‐linked immunosorbent assay (ELISA) to detect JC virus (JCV)‐specific antibodies in multiple sclerosis…”
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Assessment of JC virus DNA in blood and urine from natalizumab-treated patients by Rudick, Richard A., O'Connor, Paul W., Polman, Chris H., Goodman, Andrew D., Ray, Soma S., Griffith, Nancy M., Jurgensen, Stephanie A., Gorelik, Leonid, Forrestal, Fiona, Sandrock, Alfred W., E. Goelz, Susan

“…Objective Analyses were conducted to determine the clinical utility of measuring JC virus (JCV) DNA in blood or urine of natalizumab‐treated multiple sclerosis…”
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JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection by Wharton, Jr, Keith A, Quigley, Catherine, Themeles, Marian, Dunstan, Robert W, Doyle, Kathryn, Cahir-McFarland, Ellen, Wei, Jing, Buko, Alex, Reid, Carl E, Sun, Chao, Carmillo, Paul, Sur, Gargi, Carulli, John P, Mansfield, Keith G, Westmoreland, Susan V, Staugaitis, Susan M, Fox, Robert J, Meier, Werner, Goelz, Susan E

“…Over half of adults are seropositive for JC polyomavirus (JCV), but rare individuals develop progressive multifocal leukoencephalopathy (PML), a demyelinating…”
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Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment by Blank, Thomas, Detje, Claudia N., Spieß, Alena, Hagemeyer, Nora, Brendecke, Stefanie M., Wolfart, Jakob, Staszewski, Ori, Zöller, Tanja, Papageorgiou, Ismini, Schneider, Justus, Paricio-Montesinos, Ricardo, Eisel, Ulrich L.M., Manahan-Vaughan, Denise, Jansen, Stephan, Lienenklaus, Stefan, Lu, Bao, Imai, Yumiko, Müller, Marcus, Goelz, Susan E., Baker, Darren P., Schwaninger, Markus, Kann, Oliver, Heikenwalder, Mathias, Kalinke, Ulrich, Prinz, Marco

“…Sickness behavior and cognitive dysfunction occur frequently by unknown mechanisms in virus-infected individuals with malignancies treated with type I…”
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Beta-interferon for multiple sclerosis by Rudick, Richard A., Goelz, Susan E.

“…Interferon beta is widely used as first-line treatment for relapsing remitting multiple sclerosis (RRMS). Several products are marketed world-wide, and…”
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Assay design and sample collection can affect anti-John Cunningham virus antibody detection by Goelz, Susan E., Gorelik, Leonid, Subramanyam, Meena

“…No abstract is available for this article…”
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The effect of plasma exchange on serum anti-JC virus antibodies by Subramanyam, Meena, Plavina, Tatiana, Khatri, Bhupendra O, Fox, Robert J, Goelz, Susan E

“…Objective: Natalizumab, a highly effective treatment for multiple sclerosis (MS) and Crohn’s disease, is associated with progressive multifocal…”
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Hypomethylation of DNA from Benign and Malignant Human Colon Neoplasms by Goelz, Susan E., Vogelstein, Bert, Hamilton, Stanley R., Feinberg, Andrew P.

“…The methylation state of DNA from human colon tissue displaying neoplastic growth was determined by means of restriction endonuclease analysis. When compared…”
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Evaluation of the Incidence of Anti-JC Virus Antibodies in a Cohort of Natalizumab-Treated Patients by Pepio, Anthony M, Taylor, Lori, Jaros, Mark, Mocci, Simonetta, Yednock, Ted, Hogge, Gary S, Plavina, Tatiana, Gorelik, Leonid, Goelz, Susan E, Natarajan, Amy, Lee, Sophia, Richman, Sandra, Subramanyam, Meena

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Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling by Kantor, Aaron B, Deng, Jun, Waubant, Emmanuelle, Lin, Hua, Becker, Christopher H, Lacy, Joseph R, Perrone, Andrea M, Bennett, Donald, Goelz, Susan E

“…Abstract We applied broad-based phenotypic profiling to identify pharmacodynamic markers for interferon-beta in multiple sclerosis subjects. A strong…”
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Purification of DNA from formaldehyde fixed and paraffin embedded human tissue by Goelz, S E, Hamilton, S R, Vogelstein, B

“…The ability to isolate DNA from preserved human tissues would provide numerous experimental opportunities. In this report it is shown that DNA can be extracted…”
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Isolation and Characterization of Natural Protein-Associated Carbohydrate Ligands for E-Selectin by Patel, Thakor P, Goelz, Susan E, Lobb, Roy R, Parekh, Raj B

“…A comparative analysis of carbohydrate 'libraries' derived from cell lines binding E-selectin with differing avidity identified endogenous protein-associated…”
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Human type I interferon receptor, IFNAR, is a heavily glycosylated 120-130 kD membrane protein by Ling, L E, Zafari, M, Reardon, D, Brickelmeier, M, Goelz, S E, Benjamin, C D

“…Type I interferons (IFNs) bind and signal through cell surface receptors that share at least one common component. One candidate for such a component is the…”
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Structural and functional differences between glycosylated and non-glycosylated forms of human interferon-β (IFN-β) by RUNKEL, L, MEIER, W, PEPINSKY, R. B, KARPUSAS, M, WHITTY, A, KIMBALL, K, BRICKELMAIER, M, MULDOWNEY, C, JONES, W, GOELZ, S. E

“…Two recombinant IFN-beta products have been approved for the treatment of multiple sclerosis, a glycosylated form with the predicted natural amino acid…”
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Development of neutralizing antibodies to intramuscular interferon beta-1a (Avonex ®) by Goelz, Suzan E., Walt, L.

“…The most frequent treatment for relapsing-remitting multiple sclerosis (RRMS) is interferon beta (IFNβ). Development of neutralizing antibodies (NAbs) to IFN…”
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ELFT: a gene that directs the expression of an ELAM-1 ligand by Goelz, S E, Hession, C, Goff, D, Griffiths, B, Tizard, R, Newman, B, Chi-Rosso, G, Lobb, R

“…The LECCAMs are a family of cell adhesion molecules implicated in certain inflammatory processes. ELAM-1, a LECCAM found on the surface of activated…”
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Human Eosinophil Adherence to Vascular Endothelium Mediated by Binding to Vascular Cell Adhesion Molecule 1 and Endothelial Leukocyte Adhesion Molecule 1 by Weller, Peter F., Rand, Thomas H., Goelz, Susan E., Chi-Rosso, Gloria, Lobb, Roy R.

“…Adherence of human eosinophils to cytokine-stimulated endothelial cells, which was only partially due to CD18-dependent pathways, was also mediated by binding…”
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Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1 by Lobb, RR, Chi-Rosso, G, Leone, DR, Rosa, MD, Bixler, S, Newman, BM, Luhowskyj, S, Benjamin, CD, Dougas, IG, Goelz, SE

“…Endothelial leukocyte adhesion molecule 1 (ELAM1) is a leukocyte adhesion molecule induced on human venular endothelium in vitro and in vivo by inflammatory…”
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Distribution of Protein I in Mammalian Brain as Determined by a Detergent-Based Radioimmunoassay by Goelz, Susan E., Nestler, Eric J., Chehrazi, Bahram, Greengard, Paul

“…A radioimmunoassay has been developed for measuring protein I, a basic, neuron-specific protein associated with nerve terminals. The procedure utilizes the…”
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