Search Results - "E. G. Semin"

Composition of Populations and Durations of Persistence of Bordetella pertussis Bacteria in Patients with Whooping Cough and Contact Persons by Medkova, A. Yu, Semin, E. G., Kulikov, S. V., Nesterova, Yu. V., Babachenko, I. V., Sinyashina, L. N., Karataev, G. I.

“…Whooping cough still occupies a leading position in the group of controlled infectious diseases, despite worldwide mass vaccination. In recent decades, there…”
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Safety and immunogenicity of live intranasal pertussis vaccine GamLVP in the experimental infant hamadryas baboon model by Djidaryan, A. A., Matua, A. Z., Medkova, A. Yu, Semin, E. G., Sinyashina, L. N., Dyakov, I. N., Chernyshova, I. N., Kubrava, D. T., Amichba, A. A., Kondzariya, I. G., Mikvabiya, Z. Ya, Karataev, G. I.

“…Introduction. The Gamaleya National Center of Epidemiology and Microbiology has developed a live intranasal pertussis vaccine, GamLVP, for protection against…”
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Pre-clinical study of protective potency of candidate recombinant live pertussis vaccine for intranasal administration by Sinyashina, L. N., Semin, E. G., Medkova, A. Yu, Syundyukova, R. A., Karataev, G. I.

“…The aim of present research is studying of protective potency of candidate recombinant live pertussis vaccine (RLPV) for intranasal administration.Materials…”
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CONSTRUCTION OF RECOMBINANT ATTENUATED BORDETELLA PERTUSSIS BACTERIA OF PTXP3 GENOTYPE by Semin, E. G., Sinyashina, L. N., Medkova, A. Yu, Karataev, G. I.

“…Aim. The construction of recombinant attenuated Bordetella pertussis bacteria of ptxP3 genotype and its genetic and biological stability characteristics…”
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Immunogenicity of the drug "Live intranasal vaccine for the prevention of pertussis" (GamLPV) with a single use in healthy volunteers by Medkova, A. Yu, Lidzhiyeva, A. A., Semin, E. G., Sinyashina, L. N., Syundyukova, R. A., Snegireva, N. A., Chernyshova, I. N., Gavrilova, M. V., Bushkova, K. K., Kolobukhina, L. V., Kruzhkova, I. S., Merkulova, L. N., Rusanova, M. G., Dyakov, I. N., Karatayev, G. I.

“…Introduction. A significant increase in the incidence of pertussis in the world, including among adolescents and adults, the prevalence of mild forms of the…”
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A Clinical Study of the Safety and Tolerability of Live Nasal Vaccines for the Prevention of Pertussis by Medkova, A. Yu, Lidzhieva, A. A., Semin, E. G., Sinyashina, L. N., Sioundioukova, R. A., Dyakov, I. N., Kolobukhina, L. V., Kruzhkova, I. S., Merkulova, L N., Rusanova, M. G., Antipyat, N. A., Smetanina, S. V., Karataev, G. I.

“…Introduction. Due to the growth of laboratory-confirmed cases of pertussis among adolescents and adults, the spread of latent form of disease and the…”
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Development of a Method and a Scheme for the Use of a Live Recombinant Vaccine "GamLPV". Safety and Tolerability of Double Intranasal Vaccination of Healthy Adult Volunteers by Karataev, G. I., Medkova, A. Yu, Semin, E. G., Sinyashina, L. N., Sioundioukova, R. A., Kulikov, S. V., Snegireva, N. A., Chernishova, I. N., Gavrilova, M. V., Bushkova, K. K., Lidzhieva, A. A., Kolobukhina, L. V., Kruzhkova, I. S., Merkulova, L. N., Rusanova, M. G., Bazarova, M. V., Antipyat, N. A., Smetanina, S. V., Smolyarchuk, E. A., Dyakov, I. N.

“…Introduction . The increase in the incidence of whooping cough in children and adults of different age groups justifies the need for their revaccination and…”
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Pre-Clinical Toxicity Study and Safety Assessment of Candidate Live Pertussis Vaccine for Intranasal Administration by Sinyashina, L. N., Semin, E. G., Medkova, A. Yu, Siundiukova, R. A., Karataev, G. I.

“…Against the backdrop of mass parenteral immunization by present pertussis vaccines the incidence rate of pertussis is recorded in many countries, as well as…”
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Insertional inactivation of virulence operon in population of persistent Bordetella pertussis bacteria by Karataev, G. I., Sinyashina, L. N., Medkova, A. Yu, Semin, E. G., Shevtsova, Z. V., Matua, A. Z., Kondzariya, I. G., Amichba, A. A., Kubrava, D. T., Mikvabia, Z. Ya

“…Avirulent B. pertussis bacteria containing IS elements in the bvgAS operon were detected during the study of whooping cough patients and bacilli carriers. The…”
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CLINICAL-DIAGNOSTIC VALUE OF BORDETELLA PERTUSSIS GENETIC MARKERS IN CONTACT PERSONS IN FAMILIAL FOCI by Nesterova, Yu. V., Medkova, A. Yu, Babachenko, I. V., Semin, E. G., Kalisnikova, E. L., Sinyashina, L. N., Karataev, G. I.

“…Goal. Evaluation of duration and frequency of Bordetella pertussis DNA detection in contact persons in family foci of whooping-cough. Materials and methods…”
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PERSISTENCE OF BORDETELLA PERTUSSIS BACTERIA AND A POSSIBLE MECHANISM OF ITS FORMATION by Karataev, G I, Sinyashina, L N, Medkova, A Yu, Semin, E G

“…A growth of pertussis morbidity is observed in many countries of the world against the background of mass vaccindtion. Forms of the disease course have…”
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bvg-Negative Regulation of Repeated Sequence Transposition in Bordetella pertussis Cells by Sinyashina, L. N., Vorontsov, V. V., Semin, E. G., Chestkov, A. V., Tsygankov, Yu. D., Karataev, G. I.

“…A method of monitoring the sequential events of IS481 transposition into the ctag site of bvg operon of Bordetella pertussis has been developed. Reproduction…”
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Construction of genetically attenuated bacteria Bordetella pertussis devoid of dermonecrotic toxin activity that produces modified nontoxic form of pertussis toxin by Sinyashina, L. N., Sinyashina, L. S., Semin, E. G., Amelina, I. P., Karataev, G. I.

“…Recombinant (attenuated) bacteria Bordetella pertussis that contains a knock-out mutation in dnt gene and produces a nontoxic derivative of pertussis toxin…”
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Construction of the genetically attenuated bacteria Bordetella pertussis devoid of dermonecrotic toxin activity and producing modified nontoxic pertussis toxin form by Siniashina, L N, Siniashina, L S, Semin, E G, Amelina, I P, Karataev, G I

“…The recombinant modified (attenuated) bacteria A. pertussis were constructed. These bacteria contained knockout mutation of the dnt gene and produced nontoxic…”
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Comparative investigation of the role of the YadA, InvA, and PsaA genes in the pathogenicity of Yersinia pseudotuberculosis by Karataev, G. I., Markov, A. R., Sinyashina, L. N., Miller, G. G., Klitsunova, N. V., Titova, I. V., Semin, E. G., Goncharova, N. I., Pokrovskaya, M. S., Amelina, I. P., Amoako, K., Smirnov, G. B.

“…The role of yadA , invA , and psaA genes in virulence was studied using a Yersinia pseudotuberculosis strain isolated from a patient with Far-East scarlatinoid…”
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A comparative study of the role of the yadA, invA, and psaA genes in the pathogenicity of Yersinia pseudotuberculosis by Karataev, G I, Markov, A R, Siniashina, L N, Miller, G G, Klitsunova, N V, Titova, I V, Semin, E G, Goncharova, N I, Pokrovskaia, M S, Amelina, I P, Amoako, K, Smirnov, G B

“…The roles of yadA, invA, and psaA genes introduced into the genetic background of the Y. pseudotuberculosis strain possessing the large p VM82 plasmid in…”
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Specific features of calculation of the isobaric heat capacity and entropy of elementary substances by Fedorov, S. V., Semin, E. G., Danilevich, Ya. B.

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Insertional Inactivation of Virulence Operon in Population of Persistent Bordetella pertussis Bacteria by Karataev, G I, Sinyashina, L N, Medkova, A Yu, Semin, E G, Shevtsova, Z V, Matua, A Z, Kondzariya, I G, Amichba, A A, Kubrava, D T, Mikvabia, Z Ya

“…Avirulent B. pertussis bacteria containing IS elements in the bvgAS operon were detected during the study of whooping cough patients and bacilli carriers. The…”
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Maintenance of ecological safety in the conditions of the city by E G Tichomirova, E G Semin

“…The system of security and maintenance of ecological safety in a city is considered as the difficult system, including considerable number of objects and…”
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Epizootic pertussis focus of hamadryad baboons by A. Yu. Medkova, G. I. Karataev, Z. V. Shevtsova, A. Z. Matua, E. G. Semin, A. A. Amichba, L. N. Sinyashina, I. G. Kondzariya, V. S. Barkaya, Z. Ya. Mikvabia, A. L. Gintsburg

“…The absence of an adequate experimental animal model makes difficult study of immunity against whooping cough and its pathogenesis. Experimental whooping cough…”
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