Search Results - "E. E. Shashova"

Modern Perspective on Metabolic Reprogramming in Malignant Neoplasms by Korshunov, D. A., Kondakova, I. V., Shashova, E. E.

“…Metabolic reprogramming is one of the central features of transformed cells. Elucidation of interactions between oncogenic signaling and cell metabolic…”
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Estrogen Receptors and Ubiquitin Proteasome System: Mutual Regulation by Kondakova, Irina V, Shashova, Elena E, Sidenko, Evgenia A, Astakhova, Tatiana M, Zakharova, Liudmila A, Sharova, Natalia P

“…This review provides information on the structure of estrogen receptors (ERs), their localization and functions in mammalian cells. Additionally, the structure…”
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Role of proteasome system in prognosis of breast cancer progression by Shashova, E. E., Tarabanovskaya, N. A., Bondar, L. N.

“…The aim of this study was to compare the activity of proteasomes with different variants of tumor progression in luminal and triple-negative breast cancer…”
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The mRNA expression levels of calpains and their activity in malignant and dysplastic epithelium of the upper respiratory tract by Sidenko, E. A., Kakurina, G. V., Cheremisina, O. V., Spirina, L. V., Shashova, E. E., Korshunov, D. A., Kondakova, I. V.

“…Background. The calpain proteolytic system plays an important role in the development of cancer. Detection of early cancer in the upper respiratory tract is…”
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CIRCULATING ACTIN-BINDING PROTEINS IN PROGRESSION OF LARYNGEAL AND HYPOHARYNGEAL CANCERS by Kakurina, G. V., Shashova, E. E., Cheremisina, O. V., Choinzonov, E. L., Kondakova, I. V.

“…High aggressiveness of laryngeal and hypopharyngeal squamous cell carcinomas dictates the necessity of studying the molecular mechanisms of metastasis. Cancer…”
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Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer by Kolegova, E S, Kakurina, G V, Shashova, E E, Yunusova, N V, Spirina, L V, Sidenko, E A, Kostromitskiy, D N, Dobrodeev, A Yu, Kondakova, I V

“…The main cause of death in non-small-cell lung cancer (NSCLC) is tumor progression, in which metastasis and invasion play an important role. The metastatic…”
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Proteasome functioning in breast cancer: connection with clinical-pathological factors by Shashova, Elena E, Lyupina, Yulia V, Glushchenko, Svetlana A, Slonimskaya, Elena M, Savenkova, Olga V, Kulikov, Alexey M, Gornostaev, Nikolay G, Kondakova, Irina V, Sharova, Natalia P

“…Breast cancer is one of four oncology diseases that are most widespread in the world. Moreover, breast cancer is one of leading causes of cancer-related deaths…”
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Relationship between the mRNA expression levels of calpains 1/2 and proteins involved in cytoskeleton remodeling by Kakurina, Gelena V., Kolegova, Elena S., Shashova, Elena E., Cheremisina, Olga V., Choynzonov, Evgeniy L., Kondakova, Irina V.

“…Remodeling of the cytoskeleton underlies various cellular processes, including those associated with metastasis. The role of the proteases and proteins…”
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Beta-Catenin in Non-Small Cells Lung Cancer and Its Association with Proteasomes by Kolegova, E. S., Shashova, E. E., Kostromitskii, D. N., Dobrodeev, A. Yu, Kondakova, I. V.

“…We analyzed the content of β-catenin fractions and activity and content of proteasomes in the tissues of patients with non-small cells lung cancer. The content…”
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Expression of Genes Encoding Cell Motility Proteins during Progression of Head and Neck Squamous Cell Carcinoma by Kakurina, G. V., Kondakova, I. V., Spirina, L. V., Kolegova, E. S., Shashova, E. E., Cheremisina, O. V., Novikov, V. A., Choinzonov, E. L.

“…The model of head and neck squamous cell carcinoma (HNSCC) was used to study the expression of genes encoding actin-binding proteins depending on the type of…”
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Chymotrypsin-like activity and subunit composition of proteasomes in human cancers by Kondakova, I. V., Spirina, L. V., Koval, V. D., Shashova, E. E., Choinzonov, E. L., Ivanova, E. V., Kolomiets, L. A., Chernyshova, A. L., Slonimskaya, E. M., Usynin, E. A., Afanas’ev, S. G.

“…The activity of the proteasome, a polyfunctional enzymatic complex, is known to undergo changes during cancer development. This phenomenon is probably caused…”
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Relationship between the Levels of mRNA Expression for Protein Phosphatase 1B and Proteins Involved in Cytoskeleton Remodeling in Squamous Cell Carcinoma of the Larynx and Hypopharynx by Kakurina, G. V., Kolegova, E. S., Shashova, E. E., Velikaya, V. V., Startseva, Zh. A., Cheremisina, O. V., Choinzonov, E. L., Kondakova, I. V.

“…We analyzed the expression of genes encoding proteins involved in cytoskeleton remodeling (RND3, SNAI1, vimentin, cofilin, adenylate cyclase-associated protein…”
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PROTEASOMAL AND CALPAIN PROTEOLYSIS SYSTEMS IN DIFFERENT MOLECULAR SUBTYPES OF BREAST CANCER by Shashova, Elena E., Doroshenko, Artem V., Bondar, Lyudmila N., Slonimskaya, Elena M., Kondakova, Irina V.

“…The characteristics of calpain and proteasome systems in different molecular subtypes of breast cancer were studied. Tumor samples were obtained from 147…”
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Chymotrypsin-like and caspase-like proteasome activities in breast cancer by E. E. Shashova, I. V. Kondakova, E. M. Slonimskaya, S. A. Glushenko, E. S. Kolegova

“…The chymotrypsin-like and caspase-like proteasome activities were studied in tumor tissues of 74 patients with breast cancer (BC) NМin association with tumor…”
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THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS by E. E. Shashova, E. S. Kolegova, I. V. Kondakova, A. A. Zavyalov

“…This review presents the structure of the proteasome system, discusses its involvement in the pathogenesis of many cancers, including the process of…”
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P13 by Shashova, E, Kolegova, E, Lyupina, Yu, Slonimskaya, E, Kondakova, I, Sharova, N

“…Background The tumor microenvironment plays an important role in the progression of cancer and may be regulated by proteolysis, including the proteasomes. The…”
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Changes in the Activity of Proteasomes and Calpains in Metastases of Human Lung Cancer and Breast Cancer by Shashova, E. E., Kolegova, E. S., Zav’yalov, A. A., Slonimskaya, E. M., Kondakova, I. V.

“…In patients with breast cancer and lung cancer, chymotrypsin-like and caspase-like activities of proteasomes and total activity of calpains in the primary…”
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Changes in Proteasome Chymotrypsin-Like Activity during the Development of Human Mammary and Thyroid Carcinomas by Shashova, E. E., Astakhova, T. M., Plekhanova, A. S., Bogomyagkova, Yu. V., Lyupina, Yu. V., Sumedi, I. R., Slonimskaya, E. M., Erokhov, P. A., Abramova, E. B., Rodoman, G. V., Kuznetsov, N. A., Kondakova, I. V., Sharova, N. P., Choinzonov, E. L.

“…Changes in the proteasome chymotrypsin-like activity in mammary and thyroid carcinomas in comparison with the adjacent tissue were studied at stages…”
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Diagnostics of thyroid cancer: Limitations of the existing methods and perspectives for future developments by Sharova, N. P, Sumedi, I. R, Astakhova, T. M, Plekhanova, A. S, Lyupina, Y. V, Shashova, E. E, Kondakova, I. V, Rodoman, G. V

“…A novel approach to the development of a precise method of intraoperative diagnostics of thyroid cancer has been proposed on the basis of fundamental study of…”
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Association of mRNA Expression Levels of LRP1 and Actin-Binding Proteins with the Development of Laryngeal and Laryngopharyngeal Squamous Cell Carcinoma by Kakurina, G. V., Kolegova, Е. S., Shashova, Е. Е., Velikaya, V. V., Startseva, Zh. А., Cheremisina, О. V., Kondakova, I. V., Choinzonov, Е. L.

“…We analyzed the association of the level of mRNA expression of the main endocytosis receptor LRP1 and actin-binding proteins (ezrin, profilin-1, cofilin-1, and…”
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