Search Results - "E W Thompson"

Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent by Davis, F M, Azimi, I, Faville, R A, Peters, A A, Jalink, K, Putney, J W, Goodhill, G J, Thompson, E W, Roberts-Thomson, S J, Monteith, G R

“…Signals from the tumor microenvironment trigger cancer cells to adopt an invasive phenotype through epithelial–mesenchymal transition (EMT). Relatively little…”
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Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin by Hugo, H J, Gunasinghe, N P A D, Hollier, B G, Tanaka, T, Blick, T, Toh, A, Hill, P, Gilles, C, Waltham, M, Thompson, E W

“…Epithelial-to-mesenchymal transition (EMT) is associated with downregulated E-cadherin and frequently with decreased proliferation. Proliferation may be…”
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A dynamic in vivo model of epithelial-to-mesenchymal transitions in circulating tumor cells and metastases of breast cancer by Bonnomet, A, Syne, L, Brysse, A, Feyereisen, E, Thompson, E W, Noël, A, Foidart, J-M, Birembaut, P, Polette, M, Gilles, C

“…Epithelial-to-mesenchymal transition (EMT) processes endow epithelial cells with enhanced migratory/invasive properties and are therefore likely to contribute…”
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Cadherins in the human placenta – epithelial–mesenchymal transition (EMT) and placental development by Kokkinos, M.I, Murthi, P, Wafai, R, Thompson, E.W, Newgreen, D.F

“…Abstract Colonisation of the maternal uterine wall by the trophoblast involves a series of alterations in the behaviour and morphology of trophoblast cells…”
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Epithelial mesenchymal transition traits in human breast cancer cell lines by Blick, T., Widodo, E., Hugo, H., Waltham, M., Lenburg, M. E., Neve, R. M., Thompson, E. W.

“…Epithelial mesenchymal transition (EMT) has long been associated with breast cancer cell invasiveness and evidence of EMT processes in clinical samples is…”
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The orphan nuclear receptor LRH-1 promotes breast cancer motility and invasion by Chand, A L, Herridge, K A, Thompson, E W, Clyne, C D

“…The orphan nuclear receptor liver receptor homologue-1 (LRH-1) has roles in the development, cholesterol and bile acid homeostasis, and steroidogenesis. It…”
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MT1‐MMP expression promotes tumor growth and angiogenesis through an up‐regulation of vascular endothelial growth factor expression by Sounni, N. E., Devy, L., Hajitou, A., Frankenne, F., Munaut, C., Gilles, C., Deroanne, C., Thompson, E. W., Foidart, J. M., Noel, A.

“…ABSTRACT Membrane type 1 metalloprotease (MT1‐MMP) is a transmembrane metalloprotease that plays a major role in the extracellular matrix remodeling, directly…”
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Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells by Jamaludin, S Y N, Azimi, I, Davis, F M, Peters, A A, Gonda, T J, Thompson, E W, Roberts-Thomson, S J, Monteith, G R

“…CXC ligand (L)12 is a chemokine implicated in the migration, invasion and metastasis of cancer cells via interaction with its receptors CXC chemokine receptor…”
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Zymosan-induced inflammation stimulates neo-adipogenesis by Thomas, G.P.L, Hemmrich, K, Abberton, K.M, McCombe, D, Penington, A.J, Thompson, E.W, Morrison, W.A

“…Objective: To investigate the potential of inflammation to induce new adipose tissue formation in the in vivo environment. Methods and results: Using an…”
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Dynamic changes in high and low mammographic density human breast tissues maintained in murine tissue engineering chambers during various murine peripartum states and over time by Chew, G. L., Huang, D., Huo, C. W., Blick, T., Hill, P., Cawson, J., Frazer, H., Southey, M. D., Hopper, J. L., Henderson, M. A., Haviv, I., Thompson, E. W.

“…Mammographic density (MD) is a strong heritable risk factor for breast cancer, and may decrease with increasing parity. However, the biomolecular basis for…”
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SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines by GILLES, C, BASSUK, J. A, PULYAEVA, H, SAGE, E. H, FOIDART, J.-M, THOMPSON, E. W

“…Activation of the matrix metalloproteinase 2 (MMP-2) has been shown to play a major role in the proteolysis of extracellular matrix (ECM) associated with tumor…”
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High and low mammographic density human breast tissues maintain histological differential in murine tissue engineering chambers by Chew, G. L., Huang, D., Lin, S. J., Huo, C., Blick, T., Henderson, M. A., Hill, P., Cawson, J., Morrison, W. A., Campbell, I. G., Hopper, J. L., Southey, M. C., Haviv, I., Thompson, E. W.

“…Mammographic density (MD) is the area of breast tissue that appears radiologically white on mammography. Although high MD is a strong risk factor for breast…”
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New Insights on COX-2 in Chronic Inflammation Driving Breast Cancer Growth and Metastasis by Hugo, Honor J., Saunders, C., Ramsay, R. G., Thompson, E. W.

“…The medicinal use of aspirin stretches back to ancient times, before it was manufactured in its pure form in the late 19th century. Its accepted mechanistic…”
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Mammographic density—a review on the current understanding of its association with breast cancer by Huo, C. W., Chew, G. L., Britt, K. L., Ingman, W. V., Henderson, M. A., Hopper, J. L., Thompson, E. W.

“…There has been considerable recent interest in the genetic, biological and epidemiological basis of mammographic density (MD), and the search for causative…”
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The social aspects of EMT-MET plasticity by Thompson, E W, Haviv, I

“…Although the importance of epithelial to mesenchymal transition (EMT) is acknowledged in tumor metastasis, the contribution of the reverse process—MET—to…”
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β-Actin—an unsuitable internal control for RT-PCR by Selvey, S., Thompson, E.W., Matthaei, K., Lea, R.A., Irving, M.G., Griffiths, L.R.

“…Despite reports confirming cell-cycle dependent gene expression and a number of studies describing specific circumstances in which β-actin is also regulated,…”
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Mammary Gland Studies as Important Contributors to the Cause of Epithelial Mesenchymal Plasticity in Malignancy by Ford, H. L, Thompson, E. W

“…Issue Title: Special Issue: EMT in Mammary Development and Breast Cancer Progression; Guest Editors: Heide Ford and Erik Thompson…”
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Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3'-kinase and phospholipase C-dependent mechanism by PRICE, J. T, TIGANIS, T, AGARWAL, A, DJAKIEW, D, THOMPSON, E. W

“…Epidermal growth factor receptor (EGFR) levels predict a poor outcome in human breast cancer and are most commonly associated with proliferative effects of…”
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A collagen prolyl 4-hydroxylase inhibitor reduces adhesions after tendon injury by McCombe, D, Kubicki, M, Witschi, C, Williams, J, Thompson, E W

“…Collagen synthesis inhibition potentially can reduce adhesion formation after tendon injury but also may affect cutaneous wound healing. We hypothesized that a…”
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Phagocytosis of cross-linked gelatin matrix by human breast carcinoma cells correlates with their invasive capacity by COOPMAN, P. J, DO, M. T. H, THOMPSON, E. W, MUELLER, S. C

“…During invasion and metastasis, cancer cells interact closely with the extracellular matrix molecules by attachment, degradation, and migration. We…”
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