Search Results - "E Puscheck, Elizabeth"

Molecular biology of the stress response in the early embryo and its stem cells by Puscheck, Elizabeth E, Awonuga, Awoniyi O, Yang, Yu, Jiang, Zhongliang, Rappolee, Daniel A

“…Stress is normal during early embryogenesis and transient, elevated stress is commonplace. Stress in the milieu of the peri-implantation embryo is a summation…”
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Adverse obstetric outcomes associated with sonographically identified large uterine fibroids by Shavell, Valerie I., M.D, Thakur, Mili, M.D, Sawant, Anjali, M.D, Kruger, Michael L., M.S, Jones, Theodore B., M.D, Singh, Manvinder, M.D, Puscheck, Elizabeth E., M.D, Diamond, Michael P., M.D

“…Study Objective To determine the impact of sonographically identified large uterine fibroids (>5 cm in diameter) on obstetric outcomes. Design Retrospective…”
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Imaging in Gynecology by E Puscheck, Elizabeth

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Effects of Gravity, Microgravity or Microgravity Simulation on Early Mammalian Development by Ruden, Douglas M, Bolnick, Alan, Awonuga, Awoniyi, Abdulhasan, Mohammed, Perez, Gloria, Puscheck, Elizabeth E, Rappolee, Daniel A

“…Plant and animal life forms evolved mechanisms for sensing and responding to gravity on Earth where homeostatic needs require responses. The lack of gravity,…”
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Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation by YANG, Yu, JIANG, Zhongliang, BOLNICK, Alan, DAI, Jing, PUSCHECK, Elizabeth E, RAPPOLEE, Daniel A

“…Previous studies showed that cultured mouse trophoblast stem cells (mTSCs) have the most rapid proliferation, normal maintenance of stemness/potency, the least…”
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A Single Cell Transcriptomic Fingerprint of Stressed Premature, Imbalanced Differentiation of Embryonic Stem Cells by L Ruden, Ximena, Singh, Aditi, Marben, Teya, Tang, Wen, O Awonuga, Awoniyi, Ruden, Douglas M., E Puscheck, Elizabeth, Feng, Hao, Korzeniewski, Steven J., A Rappolee, Daniel

“…ABSTRACT Background Miscarriages cause a greater loss‐of‐life than cardiovascular diseases, but knowledge about environmentally induced miscarriages is…”
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To the point: medical education reviews—providing feedback by Bienstock, Jessica L., MD, MPH, Katz, Nadine T., MD, Cox, Susan M., MD, Hueppchen, Nancy, MD, Erickson, Sonya, MD, Puscheck, Elizabeth E., MD, MS

“…Formative feedback is an essential component of effective teaching and learning. Without it, the learner flounders. Furthermore, the Liaison Committee on…”
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Using Live Imaging and FUCCI Embryonic Stem Cells to Rank DevTox Risks: Adverse Growth Effects of PFOA Compared With DEP Are 26 Times Faster, 1,000 Times More Sensitive, and 13 Times Greater in Magnitude by Abdulhasan, Mohammed, Ruden, Ximena, You, Yuan, Harris, Sean M, Ruden, Douglas M, Awonuga, Awoniyi O, Alvero, Ayesha, Puscheck, Elizabeth E, Rappolee, Daniel A

“…Fluorescent ubiquitination-based cell cycle indicator (FUCCI) embryonic stem cells (ESCs), which fluoresce green during the S-G2-M phases, generate an S-shaped…”
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Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency by Xie, Yufen, Zhou, Sichang, Jiang, Zhongliang, Dai, Jing, Puscheck, Elizabeth E., Lee, Icksoo, Parker, Graham, Hüttemann, Maik, Rappolee, Daniel A.

“…Dysfunctional stem cell differentiation into placental lineages is associated with gestational diseases. Of the differentiated lineages available to…”
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Primary ovarian insufficiency in classic galactosemia: current understanding and future research opportunities by Thakur, Mili, Feldman, Gerald, Puscheck, Elizabeth E.

“…Classic galactosemia is an inborn error of the metabolism with devastating consequences. Newborn screening has been successful in markedly reducing the acute…”
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Low-Dose Urinary Human Chorionic Gonadotropin Is Effective for Oocyte Maturation in In Vitro Fertilization/ Intracytoplasmic Sperm Injection Cycles Independent of Body Mass Index by R Hoyos, Luis, Khan, Sana, Dai, Jing, Singh, Manvinder, P Diamond, Michael, E Puscheck, Elizabeth, O Awonuga, Awoniyi

“…Currently, there is no agreement on the optimal urinary derived human chorionic gonadotropin (u-hCG) dose requirement for initiating final oocyte maturation…”
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Benzo(a)pyrene causes PRKAA1/2-dependent ID2 loss in trophoblast stem cells by Xie, Yufen, Abdallah, Mazen E., Awonuga, Awoniyi O., Slater, Jill A., Puscheck, Elizabeth E., Rappolee, Dan A.

“…Benzo(a)pyrene (BaP), a cigarette smoke component, is metabolized to diol esters (BPDE) that bind to DNA and form mutagenic BPDE‐DNA adducts. BaP activates…”
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Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids by Schlaff, William D, Ackerman, Ronald T, Al-Hendy, Ayman, Archer, David F, Barnhart, Kurt T, Bradley, Linda D, Carr, Bruce R, Feinberg, Eve C, Hurtado, Sandra M, Kim, JinHee, Liu, Ran, Mabey, R. Garn, Owens, Charlotte D, Poindexter, Alfred, Puscheck, Elizabeth E, Rodriguez-Ginorio, Henry, Simon, James A, Soliman, Ahmed M, Stewart, Elizabeth A, Watts, Nelson B, Muneyyirci-Delale, Ozgul

“…In two identical, double-blind, randomized, 6-month phase 3 trials, elagolix (an oral gonadotropin-releasing hormone antagonist), administered with hormonal…”
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Peripheral lymphocyte telomere dysfunction: a valid surrogate marker for female fertility? by Sethuram, Ramya, Bazzi, Ali A., Salih, Sana M., Puscheck, Elizabeth E.

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Endometrial thickness is related to miscarriage rate, but not to the estradiol concentration, in cycles down-regulated with gonadotropin-releasing hormone antagonist by Detti, Laura, M.D, Yelian, Frank D., M.D., Ph.D, Kruger, Michael L., M.A, Diamond, Michael P., M.D, Rode, Anuradha, M.D, Mitwally, Mohamed F.M., M.D, Puscheck, Elizabeth E., M.D

“…In this retrospective cohort study of 102 ovarian stimulation cycles for IVF/intracytoplasmic sperm injection using GnRH antagonist and gonadotropins, we…”
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Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding associated with uterine fibroids by Al-Hendy, Ayman, Bradley, Linda, Owens, Charlotte D., Wang, Hui, Barnhart, Kurt T., Feinberg, Eve, Schlaff, William D., Puscheck, Elizabeth E., Wang, Alice, Gillispie, Veronica, Hurtado, Sandra, Muneyyirci-Delale, Ozgul, Archer, David F., Carr, Bruce R., Simon, James A., Stewart, Elizabeth A.

“…Uterine fibroids are one of the most common neoplasms found among women globally, with a prevalence of approximately 11 million women in the United States…”
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Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos by Bolnick, Alan, Abdulhasan, Mohammed, Kilburn, Brian, Xie, Yufen, Howard, Mindie, Andresen, Paul, Shamir, Alexandra M, Dai, Jing, Puscheck, Elizabeth E, Rappolee, Daniel A

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Use of hyperosmolar stress to measure stress-activated protein kinase activation and function in human HTR cells and mouse trophoblast stem cells by Zhong, Wenjing, Xie, Yufen, Wang, Yingchun, Lewis, Jennifer, Trostinskaia, Anna, Wang, Fangfei, Puscheck, Elizabeth E, Rappolee, Daniel Allen

“…Embryo growth is inversely correlated with hyperosmolar stress-induced stress-activated protein kinase/jun kinase (SAPK/JNK) induction. To examine whether…”
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Imaging and the Infertility Evaluation by JEELANI, ROOHI, PUSCHECK, ELIZABETH E

“…Ultrasound (US) has transformed the fertility evaluation. With 1 consultation, blood work and 1 to 2 USs, the female fertility status can be fully evaluated…”
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Using Live Imaging and Fluorescence Ubiquitinated Cell Cycle Indicator Embryonic Stem Cells to Distinguish G1 Cell Cycle Delays for General Stressors like Perfluoro-Octanoic Acid and Hyperosmotic Sorbitol or G2 Cell Cycle Delay for Mutagenic Stressors like Benzo(a)pyrene by Abdulhasan, Mohammed, Ruden, Ximena, Marben, Teya, Harris, Sean, Ruden, Douglas M, Awonuga, Awoniyi O, Puscheck, Elizabeth E, Rappolee, Daniel A

“…Lowest observable adverse effects level (LOAEL) is a standard point-of-departure dose in toxicology. However, first observable adverse effects level (FOAEL)…”
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