Search Results - "E, Leung"

Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death by Hayashi, K., Nikolos, F., Lee, Y. C., Jain, A., Tsouko, E., Gao, H., Kasabyan, A., Leung, H. E., Osipov, A., Jung, S. Y., Kurtova, A. V., Chan, K. S.

“…Induction of tumor cell death is the therapeutic goal for most anticancer drugs. Yet, a mode of drug-induced cell death, known as immunogenic cell death (ICD),…”
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A compound chimeric antigen receptor strategy for targeting multiple myeloma by Chen, K H, Wada, M, Pinz, K G, Liu, H, Shuai, X, Chen, X, Yan, L E, Petrov, J C, Salman, H, Senzel, L, Leung, E L H, Jiang, X, Ma, Y

“…Current clinical outcomes using chimeric-antigen receptors (CARs) against multiple myeloma show promise in the eradication of bulk disease. However, these…”
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Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor by Chen, K H, Wada, M, Pinz, K G, Liu, H, Lin, K-W, Jares, A, Firor, A E, Shuai, X, Salman, H, Golightly, M, Lan, F, Senzel, L, Leung, E L, Jiang, X, Ma, Y

“…The outlook for T-cell malignancies remain poor due to the lack of effective therapeutic options. Chimeric antigen receptor (CAR) immunotherapy has recently…”
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Addressing Population Health Care Transitions by Utilizing Swing Bed Post-Acute Care by Leung, Erika, Leung, E., Parker, H.

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Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis by MINION, J, LEUNG, E, TALBOT, E, DHEDA, K, FAI, M, MENZIES, D

“…Lipoarabinomannan (LAM) is a potential marker of active tuberculosis (TB). We performed a systematic review and meta-analysis regarding use of urinary LAM…”
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Is it possible to achieve 100 percent hand hygiene compliance during the coronavirus disease 2019 (COVID-19) pandemic? by Wong, S.-C., AuYeung, C.H.-Y., Lam, G.K.-M., Leung, E.Y.-L., Chan, V.W.-M., Yuen, K.-Y., Cheng, V.C.-C.

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Curcumin modulates DNA methylation in colorectal cancer cells by Link, Alexander, Balaguer, Francesc, Shen, Yan, Lozano, Juan Jose, Leung, Hon-Chiu E, Boland, C Richard, Goel, Ajay

“…Recent evidence suggests that several dietary polyphenols may exert their chemopreventive effect through epigenetic modifications. Curcumin is one of the most…”
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Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway by Leung, E, Xue, A, Wang, Y, Rougerie, P, Sharma, V P, Eddy, R, Cox, D, Condeelis, J

“…During metastasis to distant sites, tumor cells migrate to blood vessels. In vivo , breast tumor cells utilize a specialized mode of migration known as…”
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Diagnostic stewardship programme for urine culture: impact on antimicrobial prescription in a multi-centre cohort by Lee, A.L.H., Leung, E.C.M., Lee, M.K.P., Lai, R.W.M.

“…Restricting urine culture to patients with genuine urinary tract infection (UTI) reduces excessive antimicrobial prescription for asymptomatic bacteriuria. To…”
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Clinical Outcomes of Radiotherapy in Vaginal and Vulvar Melanoma: A High-volume Centre's Experience With a Rare Disease by Martell, K., Leung, E., Barnes, E.

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YM155 down‐regulates survivin and XIAP, modulates autophagy and induces autophagy‐dependent DNA damage in breast cancer cells by Cheng, S M, Chang, Y C, Liu, C Y, Lee, J Y C, Chan, H H, Kuo, C W, Lin, K Y, Tsai, S L, Chen, S H, Li, C F, Leung, E, Kanwar, J R, Huang, C C, Chang, J Y, Cheung, C H A

“…Background and Purpose The aim of this study was to determine the potency and molecular mechanism of action of YM155, a first‐in‐class survivin inhibitor that…”
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Negative pressure wound therapy in elective stoma reversal surgery: results of a UK district general hospital pilot by Shah, A.P., Kurian, R., Leung, E.

“…The role of negative pressure wound therapy in stoma reversal surgery remains unknown. To evaluate this, a retrospective, non-randomized, single-institution,…”
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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma by Yang, N, Leung, E L-H, Liu, C, Li, L, Eguether, T, Jun Yao, X-J, Jones, E C, Norris, D A, Liu, A, Clark, R A, Roop, D R, Pazour, G J, Shroyer, K R, Chen, J

“…Inturned (INTU), a cilia and planar polarity effector, performs prominent ciliogenic functions during morphogenesis, such as in the skin. INTU is expressed in…”
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A report from #BlueJC: Can we include more pregnant women in drug trials? by Leung, EYL

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Healthcare workers acquired COVID-19 disease from patients? An investigation by phylogenomics by Wong, R.C.W., Lee, M.K.P., Siu, G.K.H., Lee, L.K., Leung, J.S.L., Leung, E.C.M., Ho, Y.I.I., Lai, R.W.M.

“…The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When…”
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A report from #BlueJC: Why is it important to identify intimate partner violence during pregnancy? by Leung, EYL

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Salvage Re-irradiation With Single-modality Interstitial Brachytherapy for the Treatment of Recurrent Gynaecological Tumours in the Pelvis: A Multi-institutional Study by Raziee, H., D'Souza, D., Velker, V., Barnes, E., Taggar, A., Mendez, L., Leung, E.

“…Recurrent gynaecological tumours can cause significant morbidity with limited salvage options. This study investigates the strategy of salvage single-modality…”
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Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models by Zakharenko, A.L., Luzina, O.A., Sokolov, D.N., Kaledin, V.I., Nikolin, V.P., Popova, N.A., Patel, J., Zakharova, O.D., Chepanova, A.A., Zafar, A., Reynisson, J., Leung, E., Leung, I.K.H., Volcho, K.P., Salakhutdinov, N.F., Lavrik, O.I.

“…The druggability of the tyrosyl-DNA phosphodiesterase 1 (Tdp1) enzyme was investigated in conjunction with topoisomerase 1 inhibition. A novel class of…”
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The Blue Journal Club by Leung, EYL

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The Blue Journal Club by Leung, EYL

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