Search Results - "Dziedzic, Dorothy C."

Propyl gallate is a superoxide dismutase mimic and protects cultured lens epithelial cells from H2O2 insult by REDDAN, John R, GIBLIN, Frank J, SEVILLA, Michael, PADGAONKAR, Vanita, DZIEDZIC, Dorothy C, LEVERENZ, Victor R, MISRA, Indira C, CHANG, Justin S, PENA, John T

“…n-Propyl gallate (nPG) is a food preservative that is generally regarded as safe by the US FDA. It suppresses oxidation in biological systems. The mechanism by…”
Get full text

Heme Oxygenase Synthesis is Induced in Cultured Lens Epithelium by Hyperbaric Oxygen or Puromycin by PADGAONKAR, VANITA A, GIBLIN, FRANK J, FOWLER, KAREN, LEVERENZ, VICTOR R, REDDAN, JOHN R, DZIEDZIC, DOROTHY C

“…We showed previously that treatment of cultured rabbit lens epithelial cells (LECs) with hyperbaric oxygen (HBO) produced DNA strand-breaks, caused reversible…”
Get full text

Protection from Oxidative Insult in Glutathione Depleted Lens Epithelial Cells by REDDAN, JOHN R., GIBLIN, FRANK J., KADRY, RAZAN, LEVERENZ, VICTOR R., PENA, JOHN T., DZIEDZIC, DOROTHY C.

“…It has previously been shown that TEMPOL, n-propyl gallate and deferoxamine, compounds that limit the availability of Fe+2and prevent the generation of…”
Get full text

Propyl gallate is a superoxide dismutase mimic and protects cultured lens epithelial cells from H 2O 2 insult by Reddan, John R., Giblin, Frank J., Sevilla, Michael, Padgaonkar, Vanita, Dziedzic, Dorothy C., Leverenz, Victor R., Misra, Indira C., Chang, Justin S., Pena, John T.

“…n-Propyl gallate ( nPG) is a food preservative that is generally regarded as safe by the US FDA. It suppresses oxidation in biological systems. The mechanism…”
Get full text

Lens epithelium: a primary target of UVB irradiation by Hightower, K R, Reddan, J R, McCready, J P, Dziedzic, D C

“…Cultured rabbit lenses and cultured rabbit lens epithelial cells were irradiated with UV to correlate morphological changes in the epithelium with…”
Get more information

The relative roles of the glutathione redox cycle and catalase in the detoxification of H2O2 by cultured rabbit lens epithelial cells by Giblin, F J, Reddan, J R, Schrimscher, L, Dziedzic, D C, Reddy, V N

“…The relative roles of the glutathione redox cycle and catalase in the detoxification of H2O2 were investigated in cultured rabbit lens epithelial cells…”
Get more information

Analysis of α-crystallin expression in cultured mouse and rabbit lens cells by Sax, Christina M., Dziedzic, Dorothy C., Piatigorsky, Joram, Reddan, John R.

Get full text

Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells by Reddan, J R, Chepelinsky, A B, Dziedzic, D C, Piatigorsky, J, Goldenberg, E M

“…Rabbit lens epithelial cells from newborn animals exhibited limited growth when cultured under standard conditions. Cell lines were generated when explants…”
Get more information

Hyperbaric oxygen inhibits the growth of cultured rabbit lens epithelial cells without affecting glutathione level by Padgaonkar, V, Giblin, F J, Reddan, J R, Dziedzic, D C

“…Studies on human patients and experimental animals indicate that hyperbaric O2 can opacify the lens nucleus and damage the lens epithelium in vivo. Here we…”
Get more information

Insulin-like growth factors, IGF-1, IGF-2 and somatomedin C trigger cell proliferation in mammalian epithelial cells cultured in a serum-free medium by Reddan, J R, Dziedzic, D C

Get more information

Detoxification of H2O2 by cultured rabbit lens epithelial cells: participation of the glutathione redox cycle by Giblin, F J, McCready, J P, Reddan, J R, Dziedzic, D C, Reddy, V N

“…Although it has been shown that cultured rabbit lenses can adequately defend against the 0.03-0.05 mM level of H2O2 normally found in aqueous humor, the…”
Get more information

Influence of the activity of glutathione reductase on the response of cultured lens epithelial cells from young and old rabbits to hydrogen peroxide by Reddan, J R, Giblin, F J, Dziedzic, D C, McCready, J P, Schrimscher, L, Reddy, V N

“…Our previous studies on cultured rabbit lens epithelial cells from 4-day-old rabbits showed that the glutathione redox cycle plays an important role in…”
Get more information

Both human and newborn rabbit lens epithelial cells exhibit similar limited growth properties in tissue culture by Reddan, J R, McGee, S J, Goldenberg, E M, Dziedzic, D C

“…Human lens cells from 5-91-year old individuals were cultured in 8 different basal media containing fetal bovine, adult bovine, rabbit or human serum or human…”
Get more information

Establishment and characterization of a lens epithelial cell line from an eight year old rabbit by Reddan, J R, Dziedzic, D C, Mostafapour, M K, McGee, S J, Schwartz, C A

“…Although information is available on the in vitro properties of lens epithelia of young adult animals from several species, few, if any reports document the…”
Get more information