Search Results - "Dysko, Anna"
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Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides
Published in RSC chemical biology (08-06-2022)“…Oligonucleotides are rapidly emerging as powerful therapeutics for hard to treat diseases. Short single-stranded oligonucleotides can base pair with target RNA…”
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Journal Article -
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Synthesis and properties of oligonucleotides containing triazole backbone linkages and 2'-modifications for therapeutic applications
Published 01-01-2016“…Antisense oligonucleotides are short strands of DNA, which bind to their complementary mRNA target to prevent protein translation. Although conceptually…”
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Dissertation