Search Results - "Dyrberg Andersen, Jeppe"

Comparison of whole transcriptome sequencing of fresh, frozen, and formalin-fixed, paraffin-embedded cardiac tissue by Jacobsen, Stine Bøttcher, Tfelt-Hansen, Jacob, Smerup, Morten Holdgaard, Andersen, Jeppe Dyrberg, Morling, Niels

“…The use of fresh tissue for molecular studies is preferred but often impossible. Instead, frozen or formalin-fixed, paraffin-embedded (FFPE) tissues are widely…”
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Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis by Meyer, Olivia Strunge, Andersen, Mikkel Meyer, Børsting, Claus, Morling, Niels, Wulf, Hans Christian, Philipsen, Peter Alshede, Lerche, Catharina Margrethe, Dyrberg Andersen, Jeppe

“…Until recently, studying the murine methylome was restricted to sequencing-based methods. In this study we compared the global DNA methylation levels of…”
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Comparison of whole transcriptome sequencing of fresh, frozen, and formalin-fixed, paraffin-embedded cardiac tissue by Stine Bøttcher Jacobsen, Jacob Tfelt-Hansen, Morten Holdgaard Smerup, Jeppe Dyrberg Andersen, Niels Morling

“…The use of fresh tissue for molecular studies is preferred but often impossible. Instead, frozen or formalin-fixed, paraffin-embedded (FFPE) tissues are widely…”
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RYR2 Variant and Sudden Death in Patients With Dilated Cardiomyopathy by Ben-Haim, Yael, Bird, Martin, Johnson, David, Mohiddin, Saidi, Favaloro, Liliana, Dyrberg Andersen, Jeppe, Sheppard, Mary N., Pittman, Alan, Futema, Marta, Behr, Elijah R.

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SNP allele calling of Illumina Infinium Omni5-4 data using the butterfly method by Andersen, Mikkel Meyer, Christiansen, Steffan Noe, Andersen, Jeppe Dyrberg, Eriksen, Poul Svante, Morling, Niels

“…We introduce a within-sample SNP calling method, called the “butterfly method”, that improves the quality of SNP calling with the Illumina Infinium Omni5-4 SNP…”
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Evaluation of DNAmAge in paired fresh, frozen, and formalin-fixed paraffin-embedded heart tissues by Pruszkowska-Przybylska, Paulina, Dupont, Mikkel Eriksen, Jacobsen, Stine Bøttcher, Smerup, Morten, Tfelt-Hansen, Jacob, Morling, Niels, Andersen, Jeppe Dyrberg

“…The continued development in methylome analysis has enabled a more precise assessment of DNA methylation, but treatment of target tissue prior to analysis may…”
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Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts by Christiansen, Steffan Noe, Andersen, Jeppe Dyrberg, Kampmann, Marie-Louise, Liu, Jing, Andersen, Mikkel Meyer, Tfelt-Hansen, Jacob, Morling, Niels

“…The Infinium MethylationEPIC BeadChip (EPIC) is a reliable method for measuring the DNA methylation of more than 850,000 CpG positions. In clinical and…”
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DNA methylation stability in cardiac tissues kept at different temperatures and time intervals by Poggiali, Brando, Dupont, Mikkel Eriksen, Jacobsen, Stine Bøttcher, Smerup, Morten Holdgaard, Christiansen, Steffan Noe Niikanoff, Tfelt-Hansen, Jacob, Vidaki, Athina, Morling, Niels, Andersen, Jeppe Dyrberg

“…Investigating DNA methylation (DNAm) in cardiac tissues is vital for epigenetic research in cardiovascular diseases (CVDs). During cardiac surgery, biopsies…”
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Exploratory DNA methylation analysis in post-mortem heart tissue of sudden unexplained death by Sutter, Charlotte, Haas, Cordula, Bode, Peter K., Neubauer, Jacqueline, Dyrberg Andersen, Jeppe

“…Background Sudden unexplained death (SUD) is a devastating event in the young. Despite efforts to identify causal genetic variants, many cases remain…”
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Fresh and frozen cardiac tissue are comparable in DNA methylation array β-values, but formalin-fixed, paraffin-embedded tissue may overestimate DNA methylation levels by Dupont, Mikkel Eriksen, Jacobsen, Stine Bøttcher, Christiansen, Steffan Noe Niikanoff, Tfelt-Hansen, Jacob, Smerup, Morten Holdgaard, Andersen, Jeppe Dyrberg, Morling, Niels

“…Untreated fresh cardiac tissue is the optimal tissue material for investigating DNA methylation patterns of cardiac biology and diseases. However, fresh tissue…”
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A comparative study of single nucleotide variant detection performance using three massively parallel sequencing methods by Trudsø, Linea Christine, Andersen, Jeppe Dyrberg, Jacobsen, Stine Bøttcher, Christiansen, Sofie Lindgren, Congost-Teixidor, Clàudia, Kampmann, Marie-Louise, Morling, Niels

“…Massively parallel sequencing (MPS) has revolutionised clinical genetics and research within human genetics by enabling the detection of variants in multiple…”
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Evaluation of DNA variants associated with androgenetic alopecia and their potential to predict male pattern baldness by Marcińska, Magdalena, Pośpiech, Ewelina, Abidi, Sarah, Andersen, Jeppe Dyrberg, van den Berge, Margreet, Carracedo, Ángel, Eduardoff, Mayra, Marczakiewicz-Lustig, Anna, Morling, Niels, Sijen, Titia, Skowron, Małgorzata, Söchtig, Jens, Syndercombe-Court, Denise, Weiler, Natalie, Schneider, Peter M, Ballard, David, Børsting, Claus, Parson, Walther, Phillips, Chris, Branicki, Wojciech

“…Androgenetic alopecia, known in men as male pattern baldness (MPB), is a very conspicuous condition that is particularly frequent among European men and thus…”
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Differential Methylation in the GSTT1 Regulatory Region in Sudden Unexplained Death and Sudden Unexpected Death in Epilepsy by Christiansen, Steffan Noe, Jacobsen, Stine Bøttcher, Andersen, Jeppe Dyrberg, Kampmann, Marie-Louise, Trudsø, Linea Christine, Olsen, Kristine Boisen, Tfelt-Hansen, Jacob, Banner, Jytte, Morling, Niels

“…Sudden cardiac death (SCD) is a diagnostic challenge in forensic medicine. In a relatively large proportion of the SCDs, the deaths remain unexplained after…”
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Sequence variants in muscle tissue‐related genes may determine the severity of muscle contractures in cerebral palsy by Pingel, Jessica, Andersen, Jeppe Dyrberg, Christiansen, Sofie Lindgren, Børsting, Claus, Morling, Niels, Lorentzen, Jakob, Kirk, Henrik, Doessing, Simon, Wong, Christian, Nielsen, Jens Bo

“…Muscle contractures are a common complication to cerebral palsy (CP). The purpose of this study was to evaluate whether individuals with CP carry specific gene…”
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Pigmentary Markers in Danes--Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome by Johansen, Peter, Andersen, Jeppe Dyrberg, Madsen, Linnea Nørgård, Ullum, Henrik, Glud, Martin, Børsting, Claus, Gniadecki, Robert, Morling, Niels

“…To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis) contributed to melanoma predisposition, we compared pigmentary…”
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Collaborative EDNAP exercise on the IrisPlex system for DNA-based prediction of human eye colour by Chaitanya, Lakshmi, Walsh, Susan, Andersen, Jeppe Dyrberg, Ansell, Ricky, Ballantyne, Kaye, Ballard, David, Banemann, Regine, Bauer, Christiane Maria, Bento, Ana Margarida, Brisighelli, Francesca, Capal, Tomas, Clarisse, Lindy, Gross, Theresa E, Haas, Cordula, Hoff-Olsen, Per, Hollard, Clémence, Keyser, Christine, Kiesler, Kevin M, Kohler, Priscila, Kupiec, Tomasz, Linacre, Adrian, Minawi, Anglika, Morling, Niels, Nilsson, Helena, Norén, Lina, Ottens, Renée, Palo, Jukka U, Parson, Walther, Pascali, Vincenzo L, Phillips, Chris, Porto, Maria João, Sajantila, Antti, Schneider, Peter M, Sijen, Titia, Söchtig, Jens, Syndercombe-Court, Denise, Tillmar, Andreas, Turanska, Martina, Vallone, Peter M, Zatkalíková, Lívia, Zidkova, Anastassiya, Branicki, Wojciech, Kayser, Manfred

“…Abstract The IrisPlex system is a DNA-based test system for the prediction of human eye colour from biological samples and consists of a single forensically…”
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Identification of individuals from low template blood samples using whole transcriptome shotgun sequencing by Jepsen, Alberte Honoré, Kampmann, Marie-Louise, Jacobsen, Stine Bøttcher, Børsting, Claus, Andersen, Jeppe Dyrberg

“…Biological trace samples consisting of very few cells pose a challenge to conventional forensic genetic DNA analysis. RNA may be an alternative to DNA when…”
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Identification of individuals by RNA sequencing of low template samples by Andersen, Jeppe Dyrberg, Kampmann, Marie-Louise, Børsting, Claus

“…In this pilot study, we made dilutions of DNA/RNA co-extractions (1000–12.5 pg gDNA) and whole transcriptome shotgun sequenced RNA on a NovaSeq 6000 platform…”
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Altered gene expression levels of genes related to muscle function in adults with cerebral palsy by Pingel, Jessica, Vandenrijt, Jasper, Kampmann, Marie-Louise, Andersen, Jeppe Dyrberg

“…•Significant different gene expression levels were observed between adults with CP and typical developing (TD) adults in various genes.•Differences in muscle…”
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Shotgun DNA sequencing for human identification: Dynamic SNP selection and likelihood ratio calculations accounting for errors by Andersen, Mikkel Meyer, Kampmann, Marie-Louise, Jepsen, Alberte Honoré, Morling, Niels, Eriksen, Poul Svante, Børsting, Claus, Andersen, Jeppe Dyrberg

“…Shotgun sequencing is a DNA analysis method that potentially determines the nucleotide sequence of every DNA fragment in a sample, unlike PCR-based genotyping…”
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