Search Results - "Dykes, Josefina"

Label-free neuroblastoma cell separation from hematopoietic progenitor cell products using acoustophoresis - towards cell processing of complex biological samples by Olm, Franziska, Urbansky, Anke, Dykes, Josefina H., Laurell, Thomas, Scheding, Stefan

“…Processing of complex cell preparations such as blood and peripheral blood progenitor cell (PBPC) transplants using label-free technologies is challenging…”
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Label-free separation of neuroblastoma patient-derived xenograft (PDX) cells from hematopoietic progenitor cell products by acoustophoresis by Olm, Franziska, Panse, Lena, Dykes, Josefina H, Bexell, Daniel, Laurell, Thomas, Scheding, Stefan

“…Abstract Background Graft-contaminating tumor cells correlate with inferior outcome in high-risk neuroblastoma patients undergoing hematopoietic stem cell…”
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Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform by Dykes, Josefina, Lenshof, Andreas, Åstrand-Grundström, Ing-Britt, Laurell, Thomas, Scheding, Stefan

“…Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated…”
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Affinity-Bead-Mediated Enrichment of CD8+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Acoustophoresis by Urbansky, Anke, Lenshof, Andreas, Dykes, Josefina, Laurell, Thomas, Scheding, Stefan

“…Acoustophoresis is a technique that applies ultrasonic standing wave forces in a microchannel to sort cells depending on their physical properties in relation…”
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Isolation and characterization of human myeloid progenitor populations—TpoR as discriminator between common myeloid and megakaryocyte/erythroid progenitors by Edvardsson, Louise, Dykes, Josefina, Olofsson, Tor

“…The common myeloid progenitor (CMP) and its progeny, the granulocyte/monocyte progenitor (GMP) and megakaryocyte/erythrocyte progenitor (MEP), have been…”
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Rapid and effective CD3 T-cell depletion with a magnetic cell sorting program to produce peripheral blood progenitor cell products for haploidentical transplantation in children and adults by Dykes, Josefina H., Toporski, Jacek, Juliusson, Gunnar, Békássy, Albert N., Lenhoff, Stig, Lindmark, Anders, Scheding, Stefan

“…BACKGROUND: Effective T‐cell depletion is a prerequisite for haploidentical peripheral blood progenitor cell (PBPC) transplantation. This study was performed…”
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Haploidentical Stem Cell Transplantation for Refractory/Relapsed Neuroblastoma by Illhardt, Toni, Toporski, Jacek, Feuchtinger, Tobias, Turkiewicz, Dominik, Teltschik, Heiko-Manuel, Ebinger, Martin, Schwarze, Carl-Philipp, Holzer, Ursula, Lode, Holger N., Albert, Michael H., Gruhn, Bernd, Urban, Christian, Dykes, Josefina H., Teuffel, Oliver, Schumm, Michael, Handgretinger, Rupert, Lang, Peter

“…•Haploidentical stem cell transplantation is a feasible and safe treatment option that can induce long-term remission in some patients.•A melphalan-based…”
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Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine‐stimulated CD34+ human marrow cells in vitro by Edvardsson, Louise, Dykes, Josefina, Olsson, Martin L., Olofsson, Tor

“…Summary With the objective to correlate clonogenicity, gene expression and phenotype during differentiation, human bone marrow CD34+ cells were cultured in…”
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High-Dose Iodine-131-Metaiodobenzylguanidine with Haploidentical Stem Cell Transplantation and Posttransplant Immunotherapy in Children with Relapsed/Refractory Neuroblastoma by Toporski, Jacek, Garkavij, Michael, Tennvall, Jan, Øra, Ingrid, Gleisner, Katarina Sjögreen, Dykes, Josefina H, Lenhoff, Stig, Juliusson, Gunnar, Scheding, Stefan, Turkiewicz, Dominik, Békássy, Albert N

“…We evaluated the feasibility and efficacy of using high-dose iodine-131-metaiodobenzylguanidine (131 I-MIBG) followed by reduced-intensity conditioning (RIC)…”
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Novel treatment of severe combined immunodeficiency utilizing ex-vivo T-cell depleted haploidentical hematopoietic stem cell transplantation and CD45RA+ depleted donor lymphocyte infusions by Brodszki, Nicholas, Turkiewicz, Dominik, Toporski, Jacek, Truedsson, Lennart, Dykes, Josefina

“…Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment available for severe combined immunodeficiency (SCID); although, there…”
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Low incidence of hemorrhagic cystitis following ex vivo T-cell depleted haploidentical hematopoietic cell transplantation in children by Jepsen, Caroline, Turkiewicz, Dominik, Ifversen, Marianne, Heilmann, Carsten, Toporski, Jacek, Dykes, Josefina, Mellgren, Karin, Pronk, Cornelis Jan

“…Hemorrhagic cystitis (HC) is a debilitating complication following allogenic hematopoietic cell transplantation (HCT). HLA disparity and T-cell depletion have…”
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Autologous del(20q)-positive erythroid progenitor cells, re-emerging after DLI treatment of an MDS patient relapsing after allo-SCT, can provide a normal peripheral red blood cell count by DYKES, J. H, LINDMARK, A, LENHOFF, S, WINQVIST, I, JOHANSSON, B, OLOFSSON, T, OLSSON, M. L

“…A 54-year-old RhD-negative male with del(20q)-positive myelodysplastic syndrome was transplanted with bone marrow from an HLA-identical RhD-positive sibling…”
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The combination of clofarabine, etoposide, and cyclophosphamide shows limited efficacy as a bridge to transplant for children with refractory acute leukemia: results of a monitored prospective study by Toporski, Jacek, Król, Ladislav, Dykes, Josefina, Håkansson, Yvonne, Pronk, Cornelis, Turkiewicz, Dominik

“…Clofarabine has been shown to effectively induce remission in children with refractory leukemia. We conducted a prospective trial (clinicval.trials.gov…”
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Transplantation of Maternal Haploidentical TcRαβ-Depleted Stem Cells for Malignant Infantile Osteopetrosis – Optimal Timing and Rapid Hematological Recovery by Pronk, Cornelis J.H., Turkiewicz, Dominik, Dykes, Josefina, Toporski, Jacek

“…BACKGROUND: Osteopetrosis (OP), characterized by improper bone resorption is in most cases caused by dysfunctional, hematopoietic stem cell (HSC) derived…”
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Separation of Lymphocyte Populations from Peripheral Blood Progenitor Cell Products Using Affinity Bead Acoustophoresis by Urbansky, Anke, Lenshof, Andreas, Dykes, Josefina, Laurell, Thomas, Scheding, Stefan

“…Introduction: Processing of peripheral blood progenitor cells (PBPC) for clinical transplantation or research applications aims to effectively isolate or…”
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Transplantation of Haploidentical TcRaß‐Depleted Hematopoietic Cells Allows for Optimal Timing and Sustained Correction of the Metabolic Defect in Children With Infantile Osteopetrosis by Pronk, Cornelis JH, Turkiewicz, Dominik, Vult von Steyern, Kristina, Ehinger, Mats, Dykes, Josefina, Toporski, Jacek

“…ABSTRACT In osteopetrosis, osteoclast dysfunction can lead to deafness, blindness, bone marrow failure, and death. Hematopoietic cell transplantation (HCT) is…”
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Transplantation of Haploidentical TcRas-Depleted Hematopoietic Cells Allows for Optimal Timing and Sustained Correction of the Metabolic Defect in Children With Infantile Osteopetrosis by Pronk, Cornelis JH, Turkiewicz, Dominik, Vult von Steyern, Kristina, Ehinger, Mats, Dykes, Josefina, Toporski, Jacek

“…In osteopetrosis, osteoclast dysfunction can lead to deafness, blindness, bone marrow failure, and death. Hematopoietic cell transplantation (HCT) is currently…”
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Real-world clinical characterization, healthcare resource utilization and productivity loss in chronic graft versus host patients exposed to extracorporeal photopheresis in Sweden by Schain, Frida, Boissin, Constance, Laczik, Tamas, Fedeli, Stefano, Remberger, Mats, Blennow, Ola, Dykes, Josefina, Eich, Torsten, Jones, Christina, Mattsson, Jonas, Berlin, Gösta

“…Extracorporeal photopheresis (ECP) is frequently used to treat moderate-severe chronic graft versus host disease (cGVHD), however limited data exists…”
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Adverse events in apheresis: An update of the WAA registry data by Mörtzell Henriksson, M, Newman, E, Witt, V, Derfler, K, Leitner, G, Eloot, S, Dhondt, A, Deeren, D, Rock, G, Ptak, J, Blaha, M, Lanska, M, Gasova, Z, Hrdlickova, R, Ramlow, W, Prophet, H, Liumbruno, G, Mori, E, Griskevicius, A, Audzijoniene, J, Vrielink, H, Rombout, S, Aandahl, A, Sikole, A, Tomaz, J, Lalic, K, Mazic, S, Strineholm, V, Brink, B, Berlin, G, Dykes, J, Toss, F, Axelsson, C.G, Stegmayr, B, Nilsson, T, Norda, R, Knutson, F, Ramsauer, B, Wahlström, A

“…Abstract Apheresis with different procedures and devices are used for a variety of indications that may have different adverse events (AEs). The aim of this…”
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Efficient purification of CD4+ lymphocytes from peripheral blood progenitor cell products using affinity bead acoustophoresis by Lenshof, Andreas, Jamal, Arshad, Dykes, Josefina, Urbansky, Anke, Åstrand‐Grundström, Ingbritt, Laurell, Thomas, Scheding, Stefan

“…Processing of peripheral blood progenitor cells (PBPC) for clinical transplantation or research applications aims to effectively isolate or deplete specific…”
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