Search Results - "Dygalo, Nikolay N"

Dexamethasone-induced acute excitotoxic cell death in the developing brain by Lanshakov, Dmitriy A, Sukhareva, Ekaterina V, Kalinina, Tatjana S, Dygalo, Nikolay N

“…Abstract There is substantial evidence that the use of glucocorticoids in neonates is associated with an increased risk of neurodevelopmental disorders…”
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Comparative Investigation of Expression of Glutamatergic and GABAergic Genes in the Rat Hippocampus after Focal Brain Ischemia and Central LPS Administration by Kalinina, Tatyana S., Shishkina, Galina T., Lanshakov, Dmitriy A., Sukhareva, Ekaterina V., Onufriev, Mikhail V., Moiseeva, Yulia V., Gulyaeva, Natalia V., Dygalo, Nikolay N.

“…Among the responses in the early stages of stroke, activation of neurodegenerative and proinflammatory processes in the hippocampus is of key importance for…”
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Anti-Apoptotic Protein Bcl-xL Expression in the Midbrain Raphe Region Is Sensitive to Stress and Glucocorticoids by Shishkina, Galina T, Kalinina, Tatyana S, Bulygina, Veta V, Lanshakov, Dmitry A, Babluk, Ekaterina V, Dygalo, Nikolay N

“…Anti-apoptotic proteins are suggested to be important for the normal health of neurons and synapses as well as for resilience to stress. In order to determine…”
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LPS Administration Impacts Glial Immune Programs by Alternative Splicing by Babenko, Vladimir N, Shishkina, Galina T, Lanshakov, Dmitriy A, Sukhareva, Ekaterina V, Dygalo, Nikolay N

“…We performed transcriptome analysis in the hippocampus 24 h after lipopolysaccharide (LPS) administration. We observed glial-specific genes, comprised of…”
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Genes Involved by Dexamethasone in Prevention of Long-Term Memory Impairment Caused by Lipopolysaccharide-Induced Neuroinflammation by Shishkina, Galina T, Kalinina, Tatyana S, Lanshakov, Dmitriy A, Bulygina, Veta V, Komysheva, Natalya P, Bannova, Anita V, Drozd, Ulyana S, Dygalo, Nikolay N

“…Inflammatory activation within the brain is linked to a decrease in cognitive abilities; however, the molecular mechanisms implicated in the development of…”
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Identifying the Involvement of Pro-Inflammatory Signal in Hippocampal Gene Expression Changes after Experimental Ischemia: Transcriptome-Wide Analysis by Shishkina, Galina T, Gulyaeva, Natalia V, Lanshakov, Dmitriy A, Kalinina, Tatyana S, Onufriev, Mikhail V, Moiseeva, Yulia V, Sukhareva, Ekaterina V, Babenko, Vladimir N, Dygalo, Nikolay N

“…Acute cerebral ischemia induces distant inflammation in the hippocampus; however, molecular mechanisms of this phenomenon remain obscure. Here, hippocampal…”
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A critical point of male gonad development: neuroendocrine correlates of accelerated testicular growth in rats during early life by Dygalo, Nikolay N, Shemenkova, Tatjana V, Kalinina, Tatjana S, Shishkina, Galina T

“…Testis growth during early life is important for future male fertility and shows acceleration during the first months of life in humans. This acceleration…”
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Rodent Models of Depression : Neurotrophic and Neuroinflammatory Biomarkers by Stepanichev, Mikhail, Dygalo, Nikolay N., Grigoryan, Grigory, Shishkina, Galina T., Gulyaeva, Natalia

“…Rodent models are an indispensable tool for studying etiology and progress of depression. Since interrelated systems of neurotrophic factors and cytokines…”
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Stress-induced expression pattern of glutamate signaling genes associated with anhedonia by Dygalo, Nikolay N, Kalinina, Tatyana S, Shishkina, Galina T

“…Chronic stress can predispose vulnerable individuals to mood disorders, including depression. Glutamate, one of the key participants in this process, may exert…”
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Serotonergic Changes Produced by Repeated Exposure to Forced Swimming by Shishkina, Galina T., Kalinina, Tatyana S., Dygalo, Nikolay N.

“…Repeated forced swim resulted in a decrease in the concentrations of serotonin (5‐HT) and its metabolite 5‐hydroxyindoleacetic acid in the hypothalamus and…”
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Anxiogenic-like effect of chronic lipopolysaccharide is associated with increased expression of matrix metalloproteinase 9 in the rat amygdala by Shishkina, Galina T, Bannova, Anita V, Komysheva, Natalya P, Dygalo, Nikolay N

“…Pathways by which inflammatory stimuli influence behaviors can involve changes in neuronal plasticity, however, the evidence for this is still insufficient…”
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Changes in Gene Expression and Neuroinflammation in the Hippocampus after Focal Brain Ischemia: Involvement in the Long-Term Cognitive and Mental Disorders by Shishkina, Galina T., Kalinina, Tatiana S., Gulyaeva, Natalia V., Lanshakov, Dmitry A., Dygalo, Nikolay N.

“…Ischemic brain injuries are accompanied by the long-term changes in gene expression in the hippocampus, the limbic system structure, involved in the regulation…”
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The Early-Life «Programming» of Anxiety-Driven Behaviours in Adulthood as a Product of Predator-Driven Evolution by Menshanov, Petr N., Bannova, Anita V., Dygalo, Nikolay N.

“…In mammals, a persistent increase in anxiety affects animal’s behavioral activities in adulthood consistently and might be “programmed” by early-life adverse…”
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Anoxia ameliorates the dexamethasone-induced neurobehavioral alterations in the neonatal male rat pups by Menshanov, Petr N., Bannova, Anita V., Dygalo, Nikolay N.

“…Glucocorticoids and hypoxia are two essential factors affecting the brain development during labor and delivery. In addition to the neurobehavioral alterations…”
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Estimation of an area between the baseline and the effect curve parameter for lactate levels in the hippocampi of neonatal rats during anesthesia by Bannova, Anita V., Akulov, Andrey E., Menshanov, Petr N., Dygalo, Nikolay N.

“…[Display omitted] •ABEC values were estimated for lactate levels in hippocampi by MRS during anesthesia.•Dose-dependent rise in lactate levels was induced by…”
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Dexamethasone suppresses the locomotor response of neonatal rats to novel environment by Menshanov, Petr N., Bannova, Anita V., Dygalo, Nikolay N.

“…•In saline-treated pups, locomotor response to novelty observed since postnatal day 5.•Dexamethasone suppresses the pups’ locomotor response to novel…”
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Behavioral effects of glucocorticoids during the first exposures to the forced swim stress by Shishkina, Galina T., Bulygina, Veta V., Dygalo, Nikolay N.

“…Rationale Glucocorticoids facilitate coping with stress, but their high levels have been also implicated in mood disorders. Due to this duality, the role of…”
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Resistance to the development of stress-induced behavioral despair in the forced swim test associated with elevated hippocampal Bcl-xl expression by Shishkina, Galina T., Kalinina, Tatyana S., Berezova, Inna V., Bulygina, Veta V., Dygalo, Nikolay N.

“…Stress may predispose individuals toward depression through down-regulation of neurogenesis and increase in apoptosis in the brain. However, many subjects show…”
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Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: Correlations with serotonin metabolism and depressive-like behavior by Shishkina, Galina T., Kalinina, Tatyana S., Berezova, Inna V., Dygalo, Nikolay N.

“…Mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-HT) neurotransmission and…”
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Serotonergic changes produced by repeated exposure to forced swimming: correlation with behavior by Shishkina, Galina T, Kalinina, Tatyana S, Dygalo, Nikolay N

“…Repeated forced swim resulted in a decrease in the concentrations of serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid in the hypothalamus and…”
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