Search Results - "Dye, Michael J."

Mammalian NET-Seq reveals genome-wide nascent transcription coupled to RNA processing by Nojima, Takayuki, Gomes, Tomás, Grosso, Ana Rita, Kimura, Hiroshi, Dye, Michael J., Dhir, Somdutta, Carmo-Fonseca, Maria, Proudfoot, Nicholas J.

“…© Copyright © 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license…”
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Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome by Nojima, Takayuki, Dienstbier, Martin, Murphy, Shona, Proudfoot, Nicholas J., Dye, Michael J.

“…Mammalian RNA polymerase II (Pol II) transcription termination is an essential step in protein-coding gene expression that is mediated by pre-mRNA processing…”
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Exon Tethering in Transcription by RNA Polymerase II by Dye, Michael J., Gromak, Natalia, Proudfoot, Nick J.

“…There is an emerging consensus that RNA polymerase II (RNA Pol II) transcription and pre-mRNA processing are tightly coupled events. We show here that exons…”
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Terminal Exon Definition Occurs Cotranscriptionally and Promotes Termination of RNA Polymerase II by Dye, Michael J, Proudfoot, Nick J

“…Analysis of nascent transcription from the human ε- and β-globin genes shows that transcriptional termination occurs within 1.5 kb of the poly(A) site and is…”
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Integrating mRNA Processing with Transcription by Proudfoot, Nick J., Furger, Andre, Dye, Michael J.

“…The messenger RNA processing reactions of capping, splicing, and polyadenylation occur cotranscriptionally. They not only influence one another's efficiency…”
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Molecular Dissection of Mammalian RNA Polymerase II Transcriptional Termination by West, Steven, Proudfoot, Nicholas J., Dye, Michael J.

“…Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression…”
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AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination by White, Eleanor, Kamieniarz-Gdula, Kinga, Dye, Michael J, Proudfoot, Nick J

“…RNA Polymerase II (Pol II) termination is dependent on RNA processing signals as well as specific terminator elements located downstream of the poly(A) site…”
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Transcription of the human U2 snRNA genes continues beyond the 3′ box in vivo by Cuello, Paula, Boyd, Diana C., Dye, Michael J., Proudfoot, Nick J., Murphy, Shona

“…The 3′ box of the human class II snRNA genes is required for proper 3′ processing of transcripts, but how it functions is unclear. Several lines of evidence…”
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Strong Polyadenylation and Weak Pausing Combine To Cause Efficient Termination of Transcription in the Human Gγ-Globin Gene by Plant, Kathryn E., Dye, Michael J., Lafaille, Celina, Proudfoot, Nick J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multiple Transcript Cleavage Precedes Polymerase Release in Termination by RNA Polymerase II by Dye, Michael J., Proudfoot, Nick J.

“…The requirement of poly(A) signals to elicit transcription termination of RNA polymerase II (pol II) is firmly established. However, little else is known about…”
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Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene by Plant, Kathryn E, Dye, Michael J, Lafaille, Celina, Proudfoot, Nick J

“…The human gamma-globin genes form part of a 5-kb tandem duplication within the beta-globin gene cluster on chromosome 11. Despite a high degree of identity…”
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Strong Polyadenylation and Weak Pausing Combine To Cause Efficient Termination of Transcription in the Human super(G) gamma -Globin Gene by Plant, Kathryn E, Dye, Michael J, Lafaille, Celina, Proudfoot, Nick J

“…The human gamma -globin genes form part of a 5-kb tandem duplication within the beta -globin gene cluster on chromosome 11. Despite a high degree of identity…”
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Transcription of the human U2 snRNA genes continues beyond the 3' boxin vivo by Cuello, Paula, Boyd, Diana C, Dye, Michael J, Proudfoot, Nick J, Murphy, Shona

“…The 3' box of the human class II snRNA genes is required for proper 3' processing of transcripts, but how it functions is unclear. Several lines of evidence…”
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