Search Results - "Dye, Danielle E."

Antiplatelet Drug Ticagrelor Enhances Chemotherapeutic Efficacy by Targeting the Novel P2Y12-AKT Pathway in Pancreatic Cancer Cells by Elaskalani, Omar, Domenichini, Alice, Abdol Razak, Norbaini Binti, E Dye, Danielle, Falasca, Marco, Metharom, Pat

“…Extensive research has reported that extracellular ADP in the tumour microenvironment can stimulate platelets through interaction with the platelet receptor…”
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Interactions between Skeletal Muscle Myoblasts and their Extracellular Matrix Revealed by a Serum Free Culture System by Chaturvedi, Vishal, Dye, Danielle E, Kinnear, Beverley F, van Kuppevelt, Toin H, Grounds, Miranda D, Coombe, Deirdre R

“…Decellularisation of skeletal muscle provides a system to study the interactions of myoblasts with muscle extracellular matrix (ECM). This study describes the…”
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The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis by Wai Wong, Chee, Dye, Danielle E., Coombe, Deirdre R.

“…Metastasis is a major clinical problem and results in a poor prognosis for most cancers. The metastatic pathway describes the process by which cancer cells…”
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Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia by Duong, Lelinh, Radley-Crabb, Hannah G, Gardner, Joanne K, Tomay, Federica, Dye, Danielle E, Grounds, Miranda D, Pixley, Fiona J, Nelson, Delia J, Jackaman, Connie

“…Most cancers emerge in the elderly, including lung cancer and mesothelioma, yet the elderly remain an underrepresented population in pre-clinical cancer…”
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Mutations in TPM3 are a common cause of congenital fiber type disproportion by Clarke, Nigel F., Kolski, Hanna, Dye, Danielle E., Lim, Esther, Smith, Robert L. L., Patel, Rakesh, Fahey, Michael C., Bellance, Rémi, Romero, Norma B., Johnson, Edward S., Labarre-Vila, Annick, Monnier, Nicole, Laing, Nigel G., North, Kathryn N.

“…Objective Congenital fiber type disproportion (CFTD) is a rare form of congenital myopathy in which the principal histological abnormality is hypotrophy of…”
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CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy by Jackaman, Connie, Gardner, Joanne K., Tomay, Federica, Spowart, Joshua, Crabb, Hannah, Dye, Danielle E., Fox, Simon, Proksch, Stephen, Metharom, Pat, Dhaliwal, Satvinder S., Nelson, Delia J.

“…Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their…”
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Mutations in the Slow Skeletal Muscle Fiber Myosin Heavy Chain Gene ( MYH7) Cause Laing Early-Onset Distal Myopathy (MPD1) by Meredith, Christopher, Herrmann, Ralf, Parry, Cheryl, Liyanage, Khema, Dye, Danielle E., Durling, Hayley J., Duff, Rachael M., Beckman, Kaye, de Visser, Marianne, van der Graaff, Maaike M., Hedera, Peter, Fink, John K., Petty, Elizabeth M., Lamont, Phillipa, Fabian, Vicki, Bridges, Leslie, Voit, Thomas, Mastaglia, Frank L., Laing, Nigel G.

“…We previously linked Laing-type early-onset autosomal dominant distal myopathy (MPD1) to a 22-cM region of chromosome 14. One candidate gene in the region,…”
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Contribution of glycosaminoglycans to the structural and mechanical properties of tendons – A multiscale study by Al Makhzoomi, Anas K., Kirk, Thomas B., Dye, Danielle E., Allison, Garry T

“…Tendinopathy of the Achilles tendon contributes to a large range of disorders, including mechanical damage and degenerative diseases. Glycosaminoglycans…”
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The influence of glycosaminoglycan proteoglycan side chains on tensile force transmission and the nanostructural properties of Achilles tendons by Al Makhzoomi, Anas K., Kirk, Thomas B., Dye, Danielle E., Allison, Garry T.

“…This study investigates the nanostructural mechanisms that lie behind load transmission in tendons and the role of glycosaminoglycans (GAGs) in the…”
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In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics by Wong, Chee-Wai, LeGrand, Catherine F., Kinnear, Beverley F., Sobota, Radoslaw M., Ramalingam, Rajkumar, Dye, Danielle E., Raghunath, Michael, Lane, E. Birgitte, Coombe, Deirdre R.

“…The long-term expansion of keratinocytes under conditions that avoid xenogeneic components (i.e. animal serum- and feeder cell-free) generally causes…”
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Mutations and polymorphisms of the skeletal muscle α-actin gene (ACTA1) by Laing, Nigel G, Dye, Danielle E, Wallgren-Pettersson, Carina, Richard, Gabriele, Monnier, Nicole, Lillis, Suzanne, Winder, Thomas L, Lochmüller, Hanns, Graziano, Claudio, Mitrani-Rosenbaum, Stella, Twomey, Darren, Sparrow, John C, Beggs, Alan H, Nowak, Kristen J

“…The ACTA1 gene encodes skeletal muscle α-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and…”
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Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T‐ and B‐cell zones by Tomay, Federica, Wells, Kelsi, Duong, Lelinh, Tsu, Jean Wei, Dye, Danielle E, Radley‐Crabb, Hannah G, Grounds, Miranda D, Shavlakadze, Tea, Metharom, Pat, Nelson, Delia J, Jackaman, Connie

“…The average age of the human population is rising, leading to an increasing burden of age‐related diseases, including increased susceptibility to infection…”
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Interaction Between Skeletal Muscle Cells and Extracellular Matrix Proteins Using a Serum Free Culture System by Dye, Danielle E, Kinnear, Beverley F, Chaturvedi, Vishal, Coombe, Deirdre R

“…The ability to grow C2C12 myoblasts in a completely defined, serum free medium enables researchers to investigate the role of specific factors in myoblast…”
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Silk fibroin scaffolds with muscle‐like elasticity support in vitro differentiation of human skeletal muscle cells by Chaturvedi, Vishal, Naskar, Deboki, Kinnear, Beverley F., Grenik, Elizabeth, Dye, Danielle E., Grounds, Miranda D., Kundu, Subhas C., Coombe, Deirdre R.

“…Human adult skeletal muscle has a limited ability to regenerate after injury and therapeutic options for volumetric muscle loss are few. Technologies to…”
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WITHDRAWN: The Fundamental And Pathological Importance Of Oxysterol Binding Protein And Its Related Proteins by Dye, Danielle E, Bieniawski, Mark A, Wright, Sarah C E, McCauley, Angela, Coombe, Deirdre R, Mousley, Carl J

“…This article has been withdrawn by the authors as part of this review overlapped with the contents of Pietrangelo A and Ridgway ND. 2018. Cellular and…”
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Melanoma biomolecules: independently identified but functionally intertwined by Dye, Danielle E, Medic, Sandra, Ziman, Mel, Coombe, Deirdre R

“…The majority of patients diagnosed with melanoma present with thin lesions and generally these patients have a good prognosis. However, 5% of patients with…”
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The disclosure of genetic information: a human research ethics perspective by Dye, Danielle E., Youngs, Leanne, McNamara, Beverley, Goldblatt, Jack, O’Leary, Peter

“…Increasing emphasis on genetic research means that growing numbers of human research projects in Australia will involve complex issues related to genetic…”
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Actin mutations are one cause of congenital fibre type disproportion by Laing, Nigel G., Clarke, Nigel F., Dye, Danielle E., Liyanage, Khema, Walker, Kendall R., Kobayashi, Yasuaki, Shimakawa, Shuichi, Hagiwara, Tohru, Ouvrier, Robert, Sparrow, John C., Nishino, Ichizo, North, Kathryn N., Nonaka, Ikuya

“…We report three heterozygous missense mutations of the skeletal muscle alpha actin gene (ACTA1) in three unrelated cases of congenital fiber type disproportion…”
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Lipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly mice by Gardner, Joanne K, Mamotte, Cyril Ds, McGonigle, Terrence, Dye, Danielle E, Jackaman, Connie, Nelson, Delia J

“…Aging is associated with a decline in lymphocyte function however, little is known about dendritic cell (DC) subsets and aging. Aging is also associated with…”
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The impact of single gene and chromosomal disorders on hospital admissions in an adult population by Dye, Danielle E., Brameld, Kate J., Maxwell, Susannah, Goldblatt, Jack, O’Leary, Peter

“…Although the role of single gene and chromosomal disorders in pediatric illness has been recognized since the 1970s, there are few data describing the impact…”
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