Search Results - "Dyck, Brian P."

Total Asymmetric Synthesis of the Putative Structure of the Cytotoxic Diterpenoid (−)-Sclerophytin A and of the Authentic Natural Sclerophytins A and B by Bernardelli, Patrick, Moradei, Oscar M, Friedrich, Dirk, Yang, Jiong, Gallou, Fabrice, Dyck, Brian P, Doskotch, Raymond W, Lange, Tim, Paquette, Leo A

“…An enantioselective synthetic route to the thermodynamically most stable diastereomer of the structure assigned to sclerophytin A (5) has been realized. The…”
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Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines by Tucci, Fabio C., White, Nicole S., Markison, Stacy, Joppa, Margaret, Tran, Joe A., Fleck, Beth A., Madan, Ajay, Dyck, Brian P., Parker, Jessica, Pontillo, Joseph, Melissa Arellano, L., Marinkovic, Dragan, Jiang, Wanlong, Chen, Caroline W., Gogas, Kathleen R., Goodfellow, Val S., Saunders, John, Foster, Alan C., Chen, Chen

“…The melanocortin-4 receptor (MC4R) plays an important role in the regulation of energy homeostasis. Recent studies have shown that blockade of the MC4R…”
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A Novel Camphor-Derived Selenenamide That Acts as a Glutathione Peroxidase Mimetic by Back, Thomas G, Dyck, Brian P

“…A novel cyclic selenenamide 6 was prepared from the corresponding amido-substituted diselenide 5 by brominolysis and treatment with silver triflate. The…”
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1,3-Diselenetanes and 1,3-Dithietanes Derived from Camphor. Formation, Structure, Stereochemistry, and Oxidation to Selenoxide and Sulfoxide Products by Back, Thomas G, Dyck, Brian P, Parvez, Masood

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Formation of the Transient Telluroketone (1R)-3-Telluroxocamphor and Its Dimerization to the Corresponding syn- and anti-1,3-Ditelluretanes by Back, Thomas G, Dyck, Brian P, Parvez, Masood

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Studies Directed toward the Total Synthesis of Cerorubenic Acid-III. 5. A Radical Cyclization Route Leading to the Methyl Ester of the Natural Isomer1 by Paquette, Leo A, Dyck, Brian P

“…The first total synthesis of cerorubenic acid-III methyl ester is detailed. Enantiopure 4, obtained by anionic oxy-Cope rearrangement of 3, was transformed via…”
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Asymmetric electrophilic methoxyselenenylations and cyclizations with 3-camphorseleno derivatives by Back, Thomas G., Dyck, Brian P., Nan, Siqiao

“…A series of novel 3-camphor-based diselenides, differing in substitution at C-2, was prepared. The corresponding allyl selenides were used as protecting groups…”
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Studies Directed toward the Total Synthesis of Cerorubenic Acid-III. 5. A Radical Cyclization Route Leading to the Methyl Ester of the Natural Isomer 1 by Paquette, Leo A., Dyck, Brian P.

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[3aR-(3aα,4α,7α,7aα)]-2-Acetyl-4,8,8-trimethylperhydro-4,7-methano-1,2-benzisoselenazol-3a-ol by Back, T. G., Dyck, B. P., Nan, S., Parvez, M.

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