Search Results - "Dwyer, Jason R"
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Surveying silicon nitride nanopores for glycomics and heparin quality assurance
Published in Nature communications (16-08-2018)“…Polysaccharides have key biological functions and can be harnessed for therapeutic roles, such as the anticoagulant heparin. Their complexity—e.g., >100…”
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Conductance-Based Determination of Solid-State Nanopore Size and Shape: An Exploration of Performance Limits
Published in Journal of physical chemistry. C (08-11-2012)“…Knowledge of nanopore size and shape is critical for many implementations of these single-molecule sensing elements. Geometry determination by fitting the…”
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3
Editors’ Choice—Perspective—Deciphering the Glycan Kryptos by Solid-State Nanopore Single-Molecule Sensing: A Call for Integrated Advancements Across Glyco- and Nanopore Science
Published in ECS sensors plus (03-06-2024)“…Glycans, or complex carbohydrates, are information-rich biopolymers critical to many biological processes and with considerable importance in pharmaceutical…”
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4
Chemically Functionalizing Controlled Dielectric Breakdown Silicon Nitride Nanopores by Direct Photohydrosilylation
Published in ACS applied materials & interfaces (21-08-2019)“…Nanopores are a prominent enabling tool for single-molecule applications such as DNA sequencing, protein profiling, and glycomics, and the construction of…”
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5
N-Heterocyclic carbene-based gold etchants
Published in Beilstein journal of nanotechnology (21-08-2023)“…N-Heterocyclic carbenes (NHCs) are an emerging alternative to thiols for the formation of stable self-assembled monolayers (SAMs) on gold. We examined several…”
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An Atomic-Level View of Melting Using Femtosecond Electron Diffraction
Published in Science (American Association for the Advancement of Science) (21-11-2003)“…We used 600-femtosecond electron pulses to study the structural evolution of aluminum as it underwent an ultrafast laser-induced solid-liquid phase transition…”
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7
Geometry-Based Self-Assembly of Histone–DNA Nanostructures at Single-Nucleotide Resolution
Published in ACS nano (23-07-2019)“…Histones are basic protein monomers capable of interacting with DNA, providing the mechanism of DNA compaction inside the cell nucleus. The well-ordered…”
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Real-Time Profiling of Solid-State Nanopores During Solution-Phase Nanofabrication
Published in ACS applied materials & interfaces (09-11-2016)“…We describe a method for simply characterizing the size and shape of a nanopore during solution-based fabrication and surface modification, using only…”
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9
Notice who the science system honours, and how
Published in Nature (London) (01-07-2021)“…Letter to the Editor…”
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10
Femtosecond electron diffraction: ‘making the molecular movie’
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (15-03-2006)“…=0 determination, and the potential for electron acceleration to energies optimal for time-resolved diffraction…”
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11
Push-Button Method To Create Nanopores Using a Tesla-Coil Lighter
Published in ACS omega (31-01-2019)“…Controlled dielectric breakdown (CDB) of silicon nitride thin films immersed in electrolyte solution has been used to fabricate single nanofluidic channels…”
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Through a Window, Brightly: A Review of Selected Nanofabricated Thin-Film Platforms for Spectroscopy, Imaging, and Detection
Published in Applied Spectroscopy (01-09-2017)“…We present a review of the use of selected nanofabricated thin films to deliver a host of capabilities and insights spanning bioanalytical and biophysical…”
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13
Ultrafast Vibrational Dynamics of Adenine-Thymine Base Pairs in DNA Oligomers
Published in The journal of physical chemistry. B (11-09-2008)“…N−H stretching excitations of DNA oligomers containing 23 alternating adenine-thymine base pairs are studied in femtosecond two-color pump−probe experiments…”
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14
Synthetic heparan sulfate standards and machine learning facilitate the development of solid-state nanopore analysis
Published in Proceedings of the National Academy of Sciences - PNAS (16-03-2021)“…The application of solid-state (SS) nanopore devices to single-molecule nucleic acid sequencing has been challenging. Thus, the early successes in applying SS…”
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Optimizing noncontact oxygen‐plasma treatment to improve the performance of a top‐down nanofabricated surface enhanced Raman spectroscopy substrate with structurally responsive, high‐aspect‐ratio nanopillar array
Published in Journal of Raman spectroscopy (01-03-2021)“…Our use of a commercially available monolithic surface enhanced Raman spectroscopy substrate based on metallized arrays of nanopillars has been hindered by the…”
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16
An Open Source, Iterative Dual-Tree Wavelet Background Subtraction Method Extended from Automated Diffraction Pattern Analysis to Optical Spectroscopy
Published in Applied spectroscopy (01-12-2019)“…Background subtraction is a general problem in spectroscopy often addressed with application-specific techniques, or methods that introduce a variety of…”
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Photoswitchable Binary Nanopore Conductance and Selective Electronic Detection of Single Biomolecules under Wavelength and Voltage Polarity Control
Published in ACS nano (26-04-2022)“…We fabricated photoregulated thin-film nanopores by covalently linking azobenzene photoswitches to silicon nitride pores with ∼10 nm diameters. The…”
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Chemically tailoring nanopores for single-molecule sensing and glycomics
Published in Analytical and bioanalytical chemistry (01-10-2020)“…A nanopore can be fairly—but uncharitably—described as simply a nanofluidic channel through a thin membrane. Even this simple structural description holds…”
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Biofouling potential of surface-enhanced Raman scattering-based seawater quality sensors by Ulva spp
Published in Biofouling (Chur, Switzerland) (03-07-2023)“…This study investigated the biofouling potential of surface-enhanced Raman scattering (SERS)-based sensor materials in the context of marine environments…”
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Nanopore Surface Coating Delivers Nanopore Size and Shape through Conductance-Based Sizing
Published in ACS applied materials & interfaces (09-10-2013)“…The performance of nanopore single-molecule sensing elements depends intimately on their physical dimensions and surface chemical properties. These factors…”
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