Search Results - "Duzgunes, N"

D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma[S] by Nandedkar, S.D., Weihrauch, D., Xu, H., Shi, Y., Feroah, T., Hutchins, W., Rickaby, D.A., Duzgunes, N., Hillery, C.A., Konduri, K.S., Pritchard, Jr.K.A.

“…Asthma is characterized by oxidative stress and inflammation of the airways. Although proinflammatory lipids are involved in asthma, therapies targeting them…”
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Cationic porphyrin-mediated photodynamic inactivation of Candida biofilms and the effect of miconazole by Davies, A, Gebremedhin, S, Yee, M, Padilla, R J, Duzgunes, N, Konopka, K, Dorocka-Bobkowska, B

“…The formation of biofilms by Candida and the increasing resistance of Candida species to antifungals contribute to the high recurrence rates of denture…”
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Miconazole activity against Candida biofilms developed on acrylic discs by Gebremedhin, S, Dorocka-Bobkowska, B, Prylinski, M, Konopka, K, Duzgunes, N

“…Oral candidiasis in the form of Candida-associated denture stomatitis (CaDS) is associated with Candida adhesion and biofilm formation on the fitting surface…”
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Cationic lipid–DNA complexes in gene delivery: from biophysics to biological applications by Pedroso de Lima, Maria C, Simões, Sérgio, Pires, Pedro, Faneca, Henrique, Düzgüneş, Nejat

“…Great expectations from the application of gene therapy approaches to human disease have been impaired by the unsatisfactory clinical progress observed. Among…”
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Cellular changes, molecular pathways and the immune system following photodynamic treatment by Skupin-Mrugalska, P, Sobotta, L, Kucinska, M, Murias, M, Mielcarek, J, Düzgüneş, N

“…Photodynamic therapy (PDT) is a novel medical technique involving three key components: light, a photosensitizer molecule and molecular oxygen, which are…”
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Cationic liposomes for gene delivery: from biophysics to biological applications by Pedroso de Lima, M C, Neves, S, Filipe, A, Düzgüneş, N, Simões, S

“…The use of an efficient carrier for nucleic acid-based medicines is considered to be a determinant factor for the successful application of gene therapy. The…”
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Rev-binding aptamer and CMV promoter act as decoys to inhibit HIV replication by Konopka, Krystyna, Lee, Nan Sook, Rossi, John, Düzgüneş, Nejat

“…We examined whether the antiviral effect of an HIV-1 Rev-binding aptamer [RBE(apt)] could be enhanced by a ribozyme directed against the HIV-1 env gene, and…”
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The Effect of Daily Apolipoprotein A-I Mimetic Therapy on T15-Type Autoantibodies Against Oxidized Phosphatidylcholine in a Murine Model of Asthma by Konduri, K.S, Nandedkar, S.D, Weilrauch, D, Rickaby, D.A, Duzgunes, N, Pritchard, K.A

“…[...]of sacrifice samples were collected for eosinophil peroxidase activity (EPO) in the bronchioalveolar lavage fluid (BAL), lung histology, and serum IgE…”
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Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum by Simões, Sérgio, Slepushkin, Vladimir, Pires, Pedro, Gaspar, Rogério, Pedroso de Lima, Maria C., Düzgüneş, Nejat

“…Cationic liposome–DNA complexes (‘lipoplexes’) are used as gene delivery vehicles and may overcome some of the limitations of viral vectors for gene therapy…”
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Increased receptor-mediated gene delivery to the liver by protamine-enhanced-asialofetuin-lipoplexes by ARANGOA, M. A, DÜZGÜNES, N, TROS DE ILARDUYA, C

“…A novel lipidic vector composed of DOTAP/Chol liposomes, asialofetuin (AF), protamine sulfate and DNA has been developed. The resulting protamine-AF-lipoplexes…”
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Lipid mixing assays to determine fusion in liposome systems by Hoekstra, D, Düzgüneş, N

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The Effect of Daily Apolipoprotein A-I Mimetic Therapy on Pro-Inflammatory High Density Lipoprotein in a Murine Model of Asthma by Nandedkar, S.D, Konduri, K.S, Wang, J, Xu, H, Shi, Y, Rickaby, D.A, Duzgunes, N, Pritchard, K.A

“…[...]of sacrifice samples were collected for eosinophil peroxidase activity (EPO) in the bronchioalveolar lavage fluid (BAL), lung histology, 15-LOX…”
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Fusion assays monitoring intermixing of aqueous contents by Düzgüneş, N, Wilschut, J

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Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes by Konopka, Krystyna, Pretzer, Elizabeth, Felgner, Philip L., Düzgüneş, Nejat

“…Cationic liposomes may be valuable for the delivery of anti-sense oligonucleotides, ribozymes, and therapeutic genes into human immunodeficiency virus type 1…”
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The effect of secretory leukocyte proteinase inhibitor (SLPI) in a murine model of asthma by Nandedkar, S.D., Konduri, K.S., Duzgunes, N., Rickaby, D.A., Henderson, J.D.

“…Serine Leukocyte Proteinase Inhibitor (SLPI) is a naturally occurring protease that protects the epithelial surface of the lung against several serine…”
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The effect of daily budesonide therapy on IL-10 in a murine model of asthma by Konduri, K.S., Nandedkar, S.D., Rickaby, D.A., Henderson, J.D., Duzgunes, N.

“…IL-10 is an immunomodulatory cytokine that has been shown to decrease airway inflammation with a concomitant increase in airway hyper-responsiveness (AHR)…”
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Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides by SIMOES, S, SLEPUSHKIN, V, GASPAR, R, PEDROSO DE LIMA, M. C, DÜZGÜNES, N

“…Potential problems with the use of viral vectors for gene therapy necessitate the development of efficient nonviral vectors. The association of transferrin, or…”
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The anti-HIV-1 activity associated with saliva by Shine, N, Konopka, K, Düzgüneş, N

“…This review summarizes the data on the anti-human immunodeficiency virus (HIV) activity associated with saliva and the possible routes of oral transmission of…”
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Molecular mechanisms of calcium-induced membrane fusion by Papahadjopoulos, D, Nir, S, Düzgünes, N

“…We have reviewed studies on calcium-induced fusion of lipid bilayer membranes and the role of synexin and other calcium-binding proteins (annexins) in membrane…”
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Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides by SIMOES, S, SLEPUSHKIN, V, PIRES, P, GASPAR, R, PEDROSODELIMA, M. C, DÜZGÜNES, N

“…Association of a targeting ligand such as transferrin, or an endosome disrupting peptide such as GALA, with cationic liposome-DNA complexes ('lipoplexes')…”
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