Search Results - "Duvillie, B"

Different mechanisms operating during different critical time-windows reduce rat fetal beta cell mass due to a maternal low-protein or low-energy diet by Dumortier, O, Blondeau, B, Duvillié, B, Reusens, B, Bréant, B, Remacle, C

“…Aims/hypothesis Adverse events during intra-uterine life may programme organ growth and favour disease later in life. In animals, protein or energy restriction…”
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Pro-oxidant/antioxidant balance controls pancreatic β-cell differentiation through the ERK1/2 pathway by Hoarau, E, Chandra, V, Rustin, P, Scharfmann, R, Duvillie, B

“…During embryogenesis, the intrauterine milieu affects cell proliferation, differentiation, and function by modifying gene expression in susceptible cells, such…”
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Placental antiangiogenic prolactin fragments are increased in human and rat maternal diabetes by Perimenis, P., Bouckenooghe, T., Delplanque, J., Moitrot, E., Eury, E., Lobbens, S., Gosset, P., Devisme, L., Duvillie, B., Abderrahmani, A., Storme, L., Fontaine, P., Froguel, P., Vambergue, A.

“…The role of the placenta in diabetic mothers on fetal development and programming is unknown. Prolactin (PRL) produced by decidual endometrial cells may have…”
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Cell-based therapy of diabetes: What are the new sources of beta cells? by Soggia, A, Hoarau, E, Bechetoille, C, Simon, M.-T, Heinis, M, Duvillié, B

“…Abstract Diabetes affects 246 million people around the world. To date, no definitive cure has been discovered. Recent clinical trials have shed light on the…”
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Compensatory responses in mice carrying a null mutation for Ins1 or Ins2 by LEROUX, Loïc, DESBOIS, Pierrette, LAMOTTE, Luciane, DUVILLIE, Bertrand, CORDONNIER, Nathalie, JACKEROTT, Malene, JAMI, Jacques, BUCCHINI, Danielle, JOSHI, Rajiv L

“…Intrauterine growth retardation and postnatal acute diabetes result from insulin deficiency in double homozygous null mutants for Ins1 and Ins2 (Duvillié B, et…”
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Phenotypic alterations in insulin-deficient mutant mice by Duvillie, B. (Institut National de la Sante et de la Recherche Medicale, Paris, France.), Cordonnier, N, Deltour, L, Dandoy-Dron, F, Itier, J.M, Monthioux, E, Jami, J, Joshi, R.L, Bucchini, D

“…Two mouse insulin genes, Ins1 and Ins2, were disrupted and lacZ was inserted at the Ins2 locus by gene targeting. Double nullizygous insulin-deficient pups…”
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Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin by Duvillié, B, Currie, C, Chrones, T, Bucchini, D, Jami, J, Joshi, R L, Hill, D J

“…The targeted disruption of the two nonallelic insulin genes in mouse was reported previously to result in intrauterine growth retardation, severe diabetes…”
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Pancreatic development and adult diabetes by HILL, D. J, DUVILLIE, B

“…Low birth weight is an important risk factor for type 2 diabetes in later life. Maturity-onset diabetes of the young has been linked to genetic sequence…”
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Transcription factors involved in pancreas development are expressed in paediatric solid pseudopapillary tumours by Galmiche, L, Sarnacki, S, Verkarre, V, Boizet, B, Duvillie, B, Fabre, M, Jaubert, F

“…Aims:  Solid pseudopapillary tumours (SPT) are rare pancreatic tumours, especially in children. The origin of this benign tumour remains unknown. Mutations of…”
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β-cell development: the role of intercellular signals by Scharfmann, R, Duvillie, B, Stetsyuk, V, Attali, M, Filhoulaud, G, Guillemain, G

“…Understanding in detail how pancreatic endocrine cells develop is important for many reasons. From a scientific point of view, elucidation of such a complex…”
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Differential expression and imprinting status of Ins1 and Ins2 genes in extraembryonic tissues of laboratory mice by Deltour, L., Vandamme, J., Jouvenot, Y., Duvillié, B., Kelemen, K., Schaerly, P., Jami, J., Paldi, A.

“…There are two functional insulin genes in the mouse genome. The Ins2 gene is imprinted and expressed monoallelically from the paternal allele in the yolk sac…”
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Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells by YE, F, DUVILLIE, B, SCHARFMANN, R

“…The fibroblast growth factor (FGF) family consists of 22 members. In rodents, several FGFs are expressed in the pancreas, where they participate in…”
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Imprinting at the mouse Ins2 locus : Evidence for cis- and trans-allelic interactions by DUVILLIE, B, BUCCHINI, D, TONGWEI TANG, JAMI, J, PALDI, A

“…The mouse gene encoding preproinsulin 2 (Ins2) is located on the distal end of chromosome 7 in a region of several hundred kilobases that contains several…”
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Stem cells in diabetes treatment by Heinis, M, Duvillié, B

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New insights into endocrine pancreatic development: the role of environmental factors by Heinis, M, Simon, M T, Duvillié, B

“…The pancreas is a mixed gland that contains endocrine and exocrine components. Within the pancreatic islets, beta cells produce insulin and control the…”
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Increased Islet Cell Proliferation, Decreased Apoptosis, and Greater Vascularization Leading to β-Cell Hyperplasia in Mutant Mice Lacking Insulin by Duvillié, B, Currie, C, Chrones, T, Bucchini, D, Jami, J, Joshi, R. L, Hill, D. J

“…The targeted disruption of the two nonallelic insulin genes in mouse was reported previously to result in intrauterine growth retardation, severe diabetes…”
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Calsenilin is required for endocrine pancreas development in zebrafish by Stetsyuk, V., Peers, B., Mavropoulos, A., Verbruggen, V., Thisse, B., Thisse, C., Motte, P., Duvillié, B., Scharfmann, R.

“…Calsenilin/DREAM/Kchip3 is a neuronal calcium‐binding protein. It is a multifunctional protein, mainly expressed in neural tissues and implicated in regulation…”
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PO23 Contrôle de la différenciation des cellules bêta pancréatiques par les espèces réactives de l’oxygène by Hoarau, E, Chandra, V, Rustin, P, Scharfmann, R, Duvillié, B

“…Introduction Au cours de l’embryogénèse, le milieu intra-utérin influence la prolifération, la différenciation et la fonction des cellules. En particulier,…”
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CO-49: La protéine mitochondriale UCP2 contrôle le développement du pancréas endocrine by Duvillié, B, Broche, B, Ben Fradj, S, Makaci, F, Scharfmann, R, Alves-Guerra, M

“…Introduction Le développement du pancréas, et en particulier la spécification des cellules endocrines est basée sur l'expression temporelle d'une hiérarchie de…”
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P169 Analyse du rôle de HIF1α dans le développement des cellules β du pancréas embryonnaire de souris Sox9-Cre/Vhl fl/fl by Duvillié, B, Soggia, A, Scharfmann, R

“…Introduction Le développement du pancréas est régulé par une hiérarchie de facteurs de transcription. En plus de ces facteurs, on sait maintenant que plusieurs…”
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