Search Results - "Duval, Kayla E. A."
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Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models
Published in International journal of molecular sciences (01-09-2023)“…Radiation therapy (RT) has recently demonstrated promise at stimulating an enhanced immune response. The recent success of immunotherapies, such as checkpoint…”
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Immunogenetic effects of low dose (CEM43 30) magnetic nanoparticle hyperthermia and radiation in melanoma cells
Published in International journal of hyperthermia (29-11-2019)“…Objective: In this in vitro study we have used an RNA quantification technique, nanoString, and a conventional protein analysis technique (Western Blot) to…”
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Cowpea Mosaic Virus Nanoparticle Enhancement of Hypofractionated Radiation in a B16 Murine Melanoma Model
Published in Frontiers in oncology (16-12-2020)“…Virus and virus-like nanoparticles (VNPs) have been used for a variety of preclinical treatments, including anti-cancer vaccination. The Cowpea mosaic virus…”
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4
mNP hyperthermia and hypofractionated radiation activate similar immunogenetic and cytotoxic pathways
Published in International journal of hyperthermia (01-01-2020)“…The goal of this study is to better understand the immunogenetic expression and related cytotoxic responses of moderate but clinically relevant doses of…”
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Comparison of Tumor Control and Skin Damage in a Mouse Model after Ultra-High Dose Rate Irradiation and Conventional Irradiation
Published in Radiation research (01-09-2023)“…Recent studies suggest ultra-high dose rate radiation treatment (UHDR-RT) reduces normal tissue damage compared to conventional radiation treatment (CONV-RT)…”
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In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia using a Custom-Built Delivery System
Published in Journal of visualized experiments (02-07-2020)“…Hyperthermia has long been used in the treatment of cancer. Techniques have varied from the intra-tumoral insertion of hot iron rods, to systemically delivered…”
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Porcine-human glioma xenograft model. Immunosuppression and model reproducibility
Published in Cancer treatment and research communications (2024)“…Glioblastoma is the most common primary malignant and treatment-resistant human brain tumor. Rodent models have played an important role in understanding brain…”
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Journal Article -
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Immune Enhancement of Hypofractionated Radiation
Published 01-01-2020“…Radiation therapy has been a pillar of cancer treatment for decades, oftentimes in combination with surgery or chemotherapy. However, the inability to safely…”
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Dissertation