Search Results - "Dutour, Anne"
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Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location
Published in Cardiovascular research (01-10-2015)“…Human epicardial adipose tissue (EAT) is a visceral and perivascular fat that has been shown to act locally on myocardium, atria, and coronary arteries. Its…”
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Time‐course changes of muscle protein synthesis associated with obesity‐induced lipotoxicity
Published in The Journal of physiology (01-10-2012)“…Key points • Prolonged obesity leads to ectopic lipid accumulation in non‐adipose tissues, particularly in skeletal muscles, inducing metabolic dysfunctions…”
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Early humoral response to COVID-19 vaccination in patients living with obesity and diabetes in France. The COVPOP OBEDIAB study with results from the ANRS0001S COV-POPART cohort
Published in Metabolism, clinical and experimental (01-05-2023)“…Patients with diabetes and obesity are populations at high-risk for severe COVID-19 outcomes and have shown blunted immune responses when administered…”
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Untargeted Lipidomics Reveals a Specific Enrichment in Plasmalogens in Epicardial Adipose Tissue and a Specific Signature in Coronary Artery Disease
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2020)“…OBJECTIVE:Epicardial adipose tissue (EAT) is an active endocrine organ that could contribute to the pathophysiology of coronary artery disease (CAD) through…”
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An enhanced level of VCAM in transplant preservation fluid is an independent predictor of early kidney allograft dysfunction
Published in Frontiers in immunology (11-08-2022)“…Background We aimed to evaluate whether donor-related inflammatory markers found in kidney transplant preservation fluid can associate with early development…”
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Editorial: Cardiac fat in metabolic and endocrine diseases
Published in Frontiers in endocrinology (Lausanne) (31-08-2023)Get full text
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COVID-19 and Obesity: Role of Ectopic Visceral and Epicardial Adipose Tissues in Myocardial Injury
Published in Frontiers in endocrinology (Lausanne) (16-08-2021)“…In March 2020, the WHO declared coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a global pandemic…”
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Untargeted Multiomics Approach Coupling Lipidomics and Metabolomics Profiling Reveals New Insights in Diabetic Retinopathy
Published in International journal of molecular sciences (27-07-2023)“…Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) which is the main cause of vision loss in the working-age population…”
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Ectopic Fat Deposition and Diabetes Mellitus
Published in Journal of the American College of Cardiology (13-12-2016)“…[...]MRI offers excellent spatial resolution; it is now recognized to be the gold standard for adipose tissue imaging and superior to computed tomography in…”
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Browning Epicardial Adipose Tissue: Friend or Foe?
Published in Cells (Basel, Switzerland) (14-03-2022)“…The epicardial adipose tissue (EAT) is the visceral fat depot of the heart which is highly plastic and in direct contact with myocardium and coronary arteries…”
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Fully automated epicardial adipose tissue volume quantification with deep learning and relationship with CAC score and micro/macrovascular complications in people living with type 2 diabetes: the multicenter EPIDIAB study
Published in Cardiovascular diabetology (03-09-2024)“…The aim of this study (EPIDIAB) was to assess the relationship between epicardial adipose tissue (EAT) and the micro and macrovascular complications (MVC) of…”
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VAT=TAAT‐SAAT: Innovative anthropometric model to predict visceral adipose tissue without resort to CT‐Scan or DXA
Published in Obesity (Silver Spring, Md.) (01-01-2013)“…Objective: To investigate whether a combination of a selected but limited number of anthropometric measurements predicts visceral adipose tissue (VAT) better…”
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Potential Contribution of Adipose Tissue to Elevated Serum Cystatin C in Human Obesity
Published in Obesity (Silver Spring, Md.) (01-12-2009)“…Cystatin C, an endogenous inhibitor of cathepsin proteases has emerged as a biomarker of cardiovascular risk and reduced renal function. Epidemiological…”
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The Role of the Human Hypothalamus in Food Intake Networks: An MRI Perspective
Published in Frontiers in nutrition (Lausanne) (03-01-2022)“…Hypothalamus (HT), this small structure often perceived through the prism of neuroimaging as morphologically and functionally homogeneous, plays a key role in…”
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Is increased myocardial triglyceride content associated with early changes in left ventricular function? A 1H-MRS and MRI strain study
Published in Frontiers in endocrinology (Lausanne) (22-06-2023)“…Background Type 2 diabetes (T2D) and obesity induce left ventricular (LV) dysfunction. The underlying pathophysiological mechanisms remain unclear, but…”
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11β-Hydroxysteroid Dehydrogenase Type 1 mRNA is Increased in Both Visceral and Subcutaneous Adipose Tissue of Obese Patients
Published in Obesity (Silver Spring, Md.) (01-05-2006)“…Objective: Data from rodents provide evidence for a causal role of 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD‐1) in the development of obesity and its…”
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Role of Epicardial Adipose Tissue in Health and Disease: A Matter of Fat?
Published in Comprehensive Physiology (01-07-2017)“…Epicardial adipose tissue (EAT) is a small but very biologically active ectopic fat depot that surrounds the heart. Given its rapid metabolism, thermogenic…”
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Time Course of Change in Ectopic Fat Stores After Bariatric Surgery
Published in Journal of the American College of Cardiology (05-01-2016)“…More than body mass index (BMI), adiposity distribution in visceral area and in ectopic sites likely plays an important role in the obesity-related risk…”
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Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance
Published in Journal of cardiovascular magnetic resonance (06-11-2015)“…Cardiovascular complications of obesity and diabetes are major health problems. Assessing their development, their link with ectopic fat deposition and their…”
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Postnatal Programming of Glucocorticoid Metabolism in Rats Modulates High-Fat Diet–Induced Regulation of Visceral Adipose Tissue Glucocorticoid Exposure and Sensitivity and Adiponectin and Proinflammatory Adipokines Gene Expression in Adulthood
Published in Diabetes (New York, N.Y.) (01-03-2008)“…Postnatal Programming of Glucocorticoid Metabolism in Rats Modulates High-Fat Diet–Induced Regulation of Visceral Adipose Tissue Glucocorticoid Exposure and…”
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