Search Results - "Dusting, G.J"

Induction of Nitric Oxide Synthase in the Neointima Induced by a Periarterial Collar in Rabbits by Arthur, J.F, Yin, Z.L, Young, H.M, Dusting, G.J

“…A Silastic collar placed around the common carotid artery of rabbits causes the formation, within 7 days, of an atheroma-like neointima containing cells with…”
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Acetylcholine induces vasodilatation in the rabbit isolated heart through the release of nitric oxide, the endogenous nitrovasodilator by Amezcua, J.L., Dusting, G.J., Palmer, R.M.J., Moncada, S.

“…1 Acetylcholine (ACh, 0.03–3.0 μm) induced a dose‐dependent vasodilatation in the isolated Langendorff‐perfused heart of the rabbit. The vasodilatation was…”
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Characterization of receptors for platelet‐activating factor on platelets, polymorphonuclear leukocytes and macrophages by Stewart, A.G., Dusting, G.J.

“…1 We have compared the potency of the putative platelet‐activating factor (Paf) receptor antagonists (WEB 2086, L‐652,731 and BN 52021) against Paf‐induced…”
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Endothelium and the vasodilator action of rat calcitonin gene‐related peptide (CGRP) by Grace, G.C., Dusting, G.J., Kemp, B.E., Martin, T.J.

“…1 Acetylcholine and rat calcitonin gene‐related peptide (CGRP) produced a relaxation in rat isolated aortic rings which was entirely dependent on the presence…”
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Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin by Macdonald, P S, Read, M A, Dusting, G J

“…The anti-aggregatory effect of endothelium-derived relaxing factor (EDRF) on aggregation of washed, aspirin-treated platelets was compared with that of nitric…”
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Recirculation of prostacyclin (PGI2) in the dog by Dusting, G.J, Moncada, S, Vane, J.R

“…1 The inactivation of prostacyclin (PGI2) in the circulation of anaesthetized dogs has been studied by the blood‐bathed organ bioassay technique. 2 Spiral…”
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Requirement for endothelium‐derived nitric oxide in vasodilatation produced by stimulation of cholinergic nerves in rat hindquarters by Loke, K.E., Sobey, C.G., Dusting, G.J., Woodman, O.L.

“…1 We aimed to determine whether nitric oxide (NO) and/or the endothelium is involved in cholinergic neurogenic vasodilatation in the rat isolated hindquarters…”
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Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor‐α in human aortic smooth muscle and embryonic kidney cells by Moe, K. T., Aulia, S., Jiang, F., Chua, Y. L., Koh, T. H., Wong, M. C., Dusting, G. J.

“…NADPH oxidases are important sources of vascular superoxide, which has been linked to the pathogenesis of atherosclerosis. Previously we demonstrated that the…”
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Nitric oxide in cardiovascular disorders by Dusting, G J

“…Nitric oxide derived from the vascular endothelium and other cells of the cardiovascular system has important roles in physiological regulation of blood flow…”
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Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene‐related peptide in rat skin micro vasculature by Ralevic, V., Khalil, Z., Dusting, G.J., Helme, R.D.

“…1 The contributions of sensory nerves and nitric oxide (NO) to vasodilator responses to acetylcholine (ACh) and calcitonin gene‐related peptide (CGRP) were…”
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Natriuretic peptides are antihypertrophic in isolated rat cardiomyocytes by Rosenkranz, A.C., Dusting, G.J., Ritchie, R.H.

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Lipocortin protects cardiac myocytes from ischaemia in vitro by Gordon, J.M., Ritchie, R.H., Dusting, G.J.

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Effects of natriuretic peptides on atheroma-like lesions in rabbit carotid arteries by Barber, M.N., Gaspari, T.A., Dusting, G.J., Woods, R.L.

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Effects of ageing on sensory nerve function in rat skin by Khalil, Z, Ralevic, V, Bassirat, M, Dusting, G J, Helme, R D

“…Human studies have shown an age-related decrease in modulation of skin vascular reactivity by sensory nerves that correlates with a decline in wound repair…”
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Calcitonin gene-related peptide stimulates cyclic AMP formation in rat aortic smooth muscle cells by Kubota, M, Moseley, J M, Butera, L, Dusting, G J, MacDonald, P S, Martin, T J

“…In rat aortic smooth muscle cells in culture, calcitonin gene-related peptide stimulated cAMP formation in a dose-dependent manner, half-maximally effective at…”
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Dexamethasone inhibits endotoxin-induced changes in calcium and contractility in rat isolated papillary muscle by Reilly, A.M., Sun, X., Williams, D.A., Dusting, G.J.

“…This study investigates whether endotoxin-induced contractile dysfunction is associated with a defect in the modulation of calcium homeostasis and the…”
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Catecholamine release and potentiation of thromboxane A 2 production by nicotine in the greyhound by Dusting, G.J., Li, D.M.F.

“…Thromboxane A 2 was generated by infusing arachidonic acid (2.5 μg ml −1 ) into an extra‐corporeal circuit of blood withdrawn from anaesthetized dogs, and…”
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N‐nitro l‐arginine causes coronary vasoconstriction and inhibits endothelium‐dependent vasodilatation in anaesthetized greyhounds by Woodman, O.L., Dusting, G.J.

“…1 The effect of N‐nitro‐l‐arginine (l‐NNA), an inhibitor of nitric oxide biosynthesis, on large coronary artery diameter and coronary blood flow was examined…”
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Prostacyclin and vascular function: implications for hypertension and atherosclerosis by Dusting, G J, MacDonald, P S

“…Prostacyclin and endothelium-derived relaxing factor (or nitric oxide) are unstable mediators produced by the vascular endothelium, that are important for…”
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SOME DIRECT AND REFLEX CARDIOVASCULAR ACTIONS OF PROSTACYCLIN (PGI2) AND PROSTAGLANDIN E2 IN ANAESTHETIZED DOGS by CHAPPLE, D.J., DUSTING, G.J., HUGHES, R., VANE, J.R.

“…1 The aim of the study was to determine the mechanism of the hypotension and bradycardia produced by prostacyclin (PGI2). 2 Haemodynamic studies were carried…”
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