Search Results - "Dusthackeer V N, Azger"

In-vivo studies on Transitmycin, a potent Mycobacterium tuberculosis inhibitor by Mondal, Rajesh, Dusthackeer V N, Azger, Kannan, Palaniyandi, Singh, Amit Kumar, Thiruvengadam, Kannan, Manikkam, Radhakrishnan, A S, Shainaba, Balasubramanian, Mahizhaveni, Elango, Padmasini, Ebenezer Rajadas, Sam, Bharadwaj, Dinesh, Arumugam, Gandarvakottai Senthilkumar, Ganesan, Suresh, Kumar A K, Hemanth, Singh, Manjula, Patil, Shripad, U C A, Jaleel, Doble, Mukesh, R, Balagurunathan, Tripathy, Srikanth Prasad, Kumar, Vanaja

“…This study involves the in-vitro and in-vivo anti-TB potency and in-vivo safety of Transitmycin (TR) (PubChem CID:90659753)- identified to be a novel secondary…”
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Dactylides A−C, three new bioactive 22-membered macrolides produced by Dactylosporangium aurantiacum by Kumar, Pankaj, Nalli, Yedukondalu, Singh, Sanju, Wakchaure, Padmaja D., Gor, Ravi, Ghadge, Vishal A., Kim, Eunji, Ramalingam, Satish, Azger Dusthackeer, V. N., Yoon, Yeo Joon, Ganguly, Bishwajit, Shinde, Pramod B.

“…Three new 22-membered polyol macrolides, dactylides A−C ( 1−3 ), were isolated from Dactylosporangium aurantiacum ATCC 23491 employing repeated chromatographic…”
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Discovery of a highly potent novel rifampicin analog by preparing a hybrid of the precursors of the antibiotic drugs rifampicin and clofazimine by Saravanan, Pasupathy, Dusthackeer, V. N. Azger, Rajmani, R. S., Mahizhaveni, B., Nirmal, Christy R., Rajadas, Sam Ebenezer, Bhardwaj, Neerupma, Ponnuraja, C., Bhaskar, Adhin, Hemanthkumar, A. K., Ramachandran, Geetha, Tripathy, Srikanth P.

“…Tuberculosis (TB) is an infectious disease caused by the bacillus Mycobacterium tuberculosis (Mtb). The present work reports the design and synthesis of a…”
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Fatty acids-carotenoid complex: An effective anti-TB agent from the chlorella growth factor-extracted spent biomass of Chlorella vulgaris by Kumar, T.S., Josephine, A., Sreelatha, T., Azger Dusthackeer, V.N., Mahizhaveni, B., Dharani, G., Kirubagaran, R., Raja Kumar, S.

“…The multidrug-resistant (MDR) pathogen, Mycobacterium tuberculosis, still remains as one of the major threat to mankind, despite the availability of a live…”
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Risk assessment and transmission of fluoroquinolone resistance in drug-resistant pulmonary tuberculosis: a retrospective genomic epidemiology study by Nehru, Vijayalakshmi Jawaharlal, Jose Vandakunnel, Maria, Brammacharry, Usharani, Ramachandra, Venkateswari, Pradhabane, Gunavathy, Mani, Balasundaram Revathi, VN, Azger Dusthackeer, Muthaiah, Muthuraj

“…Fluoroquinolone resistance is a major challenge in treating Multidrug-Resistant Tuberculosis globally. The GenoType MTBDR sl Ver 2.0, endorsed by the WHO, was…”
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Dodecanoic acid & palmitic acid disarms rifampicin resistance by putatively targeting mycobacterial efflux pump Rv1218c by Nirmal, Christy, Rajadas, Sam, Balasubramanian, Mahizhaveni, Magdaline, Divya, Chilamakuru, Naresh, Dinesh, Rajkumar, Radhakrishnan, A, Paraman, Ramalingam, Mondal, Rajesh, Azger Dusthackeer, V

“…Background & objectives: Drug-resistant tuberculosis (TB) jeopardizes the treatment process with poor outcomes. Efflux pumps (EPs) belonging to the ABC…”
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Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance by Peraman, Ramalingam, Sure, Sathish Kumar, Dusthackeer, V. N. Azger, Chilamakuru, Naresh Babu, Yiragamreddy, Padmanabha Reddy, Pokuri, Chiranjeevi, Kutagulla, Vinay Kumar, Chinni, Santhivardhan

“…Background Despite the various strategies undertaken in the clinical practice, the mortality rate due to antibiotic-resistant microbes has been markedly…”
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New synergistic benzoquinone scaffolds as inhibitors of mycobacterial cytochrome bc1 complex to treat multi-drug resistant tuberculosis by Chilamakuru, Naresh Babu, VN, Azger Dusthackeer, G, Varadaraj Bhat, Pallaprolu, Nikhil, Dande, Aishwarya, Nair, Dina, Pemmadi, Raghuveer Varma, Reddy Y, Padmanabha, Peraman, Ramalingam

“…Through a comprehensive molecular docking study, a unique series of naphthoquinones clubbed azetidinone scaffolds was arrived with promising binding affinity…”
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Synthesis and biological evaluation of 2,4,5-trisubstituted thiazoles as antituberculosis agents effective against drug-resistant tuberculosis by Karale, Uttam B., Krishna, Vagolu Siva, Krishna, E. Vamshi, Choudhari, Amit S., Shukla, Manjulika, Gaikwad, Vikas R., Mahizhaveni, B., Chopra, Sidharth, Misra, Sunil, Sarkar, Dhiman, Sriram, Dharmarajan, Dusthackeer, V.N. Azger, Rode, Haridas B.

“…The dormant and resistant form of Mycobacterium tuberculosis presents a challenge in developing new anti-tubercular drugs. Herein, we report the synthesis and…”
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Synthesis and evaluation of α-aminoacyl amides as antitubercular agents effective on drug resistant tuberculosis by Makane, Vitthal B., Krishna, Vagolu Siva, Krishna, E. Vamshi, Shukla, Manjulika, Mahizhaveni, B., Misra, Sunil, Chopra, Sidharth, Sriram, Dharmarajan, Dusthackeer, V.N. Azger, Rode, Haridas B.

“…The development of an effective antitubercular agent is a challenge due to the complex nature of tuberculosis. Herein, we report the synthesis and evaluation…”
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Retrieval of Mycobacterium tuberculosis cultures suspended in phosphate buffered saline by Dusthackeer, V.N. Azger, Nagarajan, P, Das, Dasarathi, Kumar, Vanaja, Selvakumar, N

“…Abstract One hundred and twenty-seven of 130 isolates of Mycobacterium tuberculosis , suspended in phosphate buffered saline (PBS) and stored at ambient…”
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Extrapulmonary Tuberculosis—An Update on the Diagnosis, Treatment and Drug Resistance by Gopalaswamy, Radha, Dusthackeer, V. N. Azger, Kannayan, Silambuchelvi, Subbian, Selvakumar

“…Pathogenic Mycobacterium tuberculosis complex organisms (MTBC) primarily cause pulmonary tuberculosis (PTB); however, MTBC are also capable of causing disease…”
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Variants of katG, inhA and nat genes are not associated with mutations in efflux pump genes (mmpL3 and mmpL7) in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from India by Unissa, A. Nusrath, Dusthackeer, V.N. Azger, Kumar, Micheal Prem, Nagarajan, P., Sukumar, S., Kumari, V. Indira, Lakshmi, A. Ramya, Hanna, L.E.

“…To understand the impact of efflux pump genes such as mmpL3 and mmpL7 on isoniazid (INH) resistance and to correlate with presence or absence of mutations in…”
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