Optimization and clinical use of multisegment intensity-modulated radiation therapy for high-dose conformal therapy

Intensity-modulated radiation therapy (IMRT) may be performed with many different treatment delivery techniques. This article summarizes the clinical use and optimization of multisegment IMRT plans that have been used to treat more than 350 patients with IMRT over the last 4.5 years. More than 475 s...

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Bibliographic Details
Published in:	Seminars in radiation oncology Vol. 9; no. 1; pp. 60 - 77
Main Authors:	Fraass, Benedick A., Kessler, Marc L., McShan, Daniel L., Marsh, Lon H., Watson, Barbara A., Dusseau, Wendy J., Eisbruch, Avi, Sandler, Howard M., Lichter, Allen S.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 1999
Subjects:	Abdominal Neoplasms - radiotherapy Brain Neoplasms - radiotherapy Breast Neoplasms - radiotherapy Female Head and Neck Neoplasms - radiotherapy Humans Male Neoplasms - radiotherapy Patient Care Planning Prostatic Neoplasms - radiotherapy Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Radiotherapy, Conformal - instrumentation Radiotherapy, Conformal - methods Thoracic Neoplasms - radiotherapy
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Summary:	Intensity-modulated radiation therapy (IMRT) may be performed with many different treatment delivery techniques. This article summarizes the clinical use and optimization of multisegment IMRT plans that have been used to treat more than 350 patients with IMRT over the last 4.5 years. More than 475 separate clinical IMRT plans are reviewed, including treatments of brain, head and neck, thorax, breast and chest wall, abdomen, pelvis, prostate, and other sites. Clinical planning, plan optimization, and treatment delivery are summarized, including efforts to minimize the number of additional intensity-modulated segments needed for particular planning protocols. Interactive and automated optimization of segmental and full IMRT approaches are illustrated, and automation of the segmental IMRT planning process is discussed.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1053-4296 1532-9461
DOI:	10.1016/S1053-4296(99)80055-1