Search Results - "Dussaud, Sebastien"

Fructooligosaccharides benefits on glucose homeostasis upon high-fat diet feeding require type 2 conventional dendritic cells by Gélineau, Adélaïde, Marcelin, Geneviève, Ouhachi, Melissa, Dussaud, Sébastien, Voland, Lise, Manuel, Raoul, Baba, Ines, Rouault, Christine, Yvan-Charvet, Laurent, Clément, Karine, Tussiwand, Roxane, Huby, Thierry, Gautier, Emmanuel L.

“…Diet composition impacts metabolic health and is now recognized to shape the immune system, especially in the intestinal tract. Nutritional imbalance and…”
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The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells by Collombat, Patrick, Xu, Xiaobo, Ravassard, Philippe, Sosa-Pineda, Beatriz, Dussaud, Sébastien, Billestrup, Nils, Madsen, Ole D., Serup, Palle, Heimberg, Harry, Mansouri, Ahmed

“…We have previously reported that the loss of Arx and/or Pax4 gene activity leads to a shift in the fate of the different endocrine cell subtypes in the mouse…”
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Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor function by Baba, Kenkichi, Benleulmi-Chaachoua, Abla, Journé, Anne-Sophie, Kamal, Maud, Guillaume, Jean-Luc, Dussaud, Sébastien, Gbahou, Florence, Yettou, Katia, Liu, Cuimei, Contreras-Alcantara, Susana, Jockers, Ralf, Tosini, Gianluca

“…The formation of G protein (heterotrimeric guanine nucleotide-binding protein)-coupled receptor (GPCR) heteromers enables signaling diversification and holds…”
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Role of IL-18 in adipose tissue remodeling and metabolic dysfunction by Lana, Jaqueline Pereira, de Oliveira, Marina Chaves, Silveira, Ana Letícia Malheiros, Yamada, Letícia Tamie Paiva, Costa, Kátia Anunciação, da Silva, Simone Vargas, de Assis-Ferreira, Agatha, Gautier, Emmanuel L., Dussaud, Sébastien, Pinho, Vanessa, Teixeira, Mauro Martins, Marcelin, Geneviève, Clément, Karine, Ferreira, Adaliene Versiani Matos

“…Background/objectives Proinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects against…”
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Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion by Guilbaud, Emma, Barouillet, Thibault, Ilie, Marius, Borowczyk, Coraline, Ivanov, Stoyan, Sarrazy, Vincent, Vaillant, Nathalie, Ayrault, Marion, Castiglione, Alexia, Rignol, Guylène, Brest, Patrick, Bazioti, Venetia, Zaitsev, Konstantin, Lebrigand, Kevin, Dussaud, Sébastien, Magnone, Virginie, Bertolotto, Corine, Marchetti, Sandrine, Irondelle, Marie, Goldberg, Ira, Huby, Thierry, Westerterp, Marit, Gautier, Emmanuel L., Mari, Bernard, Barbry, Pascal, Hofman, Paul, Yvan-Charvet, Laurent

“…Cholesterol efflux pathways could be exploited in tumor biology to unravel cancer vulnerabilities. A mouse model of lung-tumor-bearing KRASG12D mutation with…”
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Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation by Merour, Emeric, Hmidan, Hatem, Marie, Corentine, Helou, Pierre-Henri, Lu, Haiyang, Potel, Antoine, Hure, Jean-Baptiste, Clavairoly, Adrien, Shih, Yi Ping, Goudarzi, Salman, Dussaud, Sebastien, Ravassard, Philippe, Hafizi, Sassan, Lo, Su Hao, Hassan, Bassem A, Parras, Carlos

“…The differentiation of oligodendroglia from oligodendrocyte precursor cells (OPCs) to complex and extensive myelinating oligodendrocytes (OLs) is a multistep…”
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C9ORF72 knockdown triggers FTD-like symptoms and cell pathology in mice by Lopez-Herdoiza, Maria-Belen, Bauché, Stephanie, Wilmet, Baptiste, Le Duigou, Caroline, Roussel, Delphine, Frah, Magali, Béal, Jonas, Devely, Gabin, Boluda, Susana, Frick, Petra, Bouteiller, Delphine, Dussaud, Sébastien, Guillabert, Pierre, Dalle, Carine, Dumont, Magali, Camuzat, Agnes, Saracino, Dario, Barbier, Mathieu, Bruneteau, Gaelle, Ravassard, Phillippe, Neumann, Manuela, Nicole, Sophie, Le Ber, Isabelle, Brice, Alexis, Latouche, Morwena

“…The GGGGCC intronic repeat expansion within is the most common genetic cause of ALS and FTD. This mutation results in toxic gain of function through…”
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Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols by Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien

“…Human induced pluripotent stem cells (iPSCs) represent a powerful human model to study cardiac disease in vitro, notably channelopathies and sarcomeric…”
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Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells by Yaniz-Galende, Elisa, Roux, Maguelonne, Nadaud, Sophie, Mougenot, Nathalie, Bouvet, Marion, Claude, Olivier, Lebreton, Guillaume, Blanc, Catherine, Pinet, Florence, Atassi, Fabrice, Perret, Claire, Dierick, France, Dussaud, Sébastien, Leprince, Pascal, Trégouët, David-Alexandre, Marazzi, Giovanna, Sassoon, David, Hulot, Jean-Sébastien

“…Pw1 gene expression is a marker of adult stem cells in a wide range of tissues. PW1-expressing cells are detected in the heart but are not well characterized…”
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes by Gainullina, Anastasiia, Mogilenko, Denis A., Huang, Li-Hao, Todorov, Helena, Narang, Vipin, Kim, Ki-Wook, Yng, Lim Sheau, Kent, Andrew, Jia, Baosen, Seddu, Kumba, Krchma, Karen, Wu, Jun, Crozat, Karine, Tomasello, Elena, Dress, Regine, See, Peter, Scott, Charlotte, Gibbings, Sophie, Bajpai, Geetika, Desai, Jigar V., Maier, Barbara, This, Sébastien, Wang, Peter, Aguilar, Stephanie Vargas, Poupel, Lucie, Dussaud, Sébastien, Zhou, Tyng-An, Angeli, Veronique, Blander, J. Magarian, Choi, Kyunghee, Dalod, Marc, Dzhagalov, Ivan, Gautier, Emmanuel L., Jakubzick, Claudia, Lavine, Kory, Lionakis, Michail S., Paidassi, Helena, Sieweke, Michael H., Ginhoux, Florent, Guilliams, Martin, Benoist, Christophe, Merad, Miriam, Randolph, Gwendalyn J., Sergushichev, Alexey, Artyomov, Maxim N.

“…The diversity of mononuclear phagocyte (MNP) subpopulations across tissues is one of the key physiological characteristics of the immune system. Here, we focus…”
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A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element by van Arensbergen, Joris, Dussaud, Sebastien, Pardanaud-Glavieux, Corinne, García-Hurtado, Javier, Sauty, Claire, Guerci, Aline, Ferrer, Jorge, Ravassard, Philippe

“…Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms. Gene activation is dependent on…”
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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis by Tran, Sophie, Baba, Ines, Poupel, Lucie, Dussaud, Sébastien, Moreau, Martine, Gélineau, Adélaïde, Marcelin, Geneviève, Magréau-Davy, Elissa, Ouhachi, Melissa, Lesnik, Philippe, Boissonnas, Alexandre, Le Goff, Wilfried, Clausen, Björn E., Yvan-Charvet, Laurent, Sennlaub, Florian, Huby, Thierry, Gautier, Emmanuel L.

“…Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the adult independently from monocytes. However, how they are maintained…”
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Loss of embryonically-derived Kupffer cells during hypercholesterolemia accelerates atherosclerosis development by Fima, Rebecca, Dussaud, Sébastien, Benbida, Cheïma, Blanchet, Margault, Lanthiez, François, Poupel, Lucie, Brambilla, Claudia, Gélineau, Adélaïde, Dessena, Mattia, Blanc, Marina, Lerévérend, Cédric, Moreau, Martine, Boissonnas, Alexandre, Gautier, Emmanuel L., Huby, Thierry

“…Hypercholesterolemia is a major risk factor for atherosclerosis and associated cardiovascular diseases. The liver plays a key role in the regulation of plasma…”
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Lentiviral Mediated Production of Transgenic Mice: A Simple and Highly Efficient Method for Direct Study of Founders by Dussaud, Sébastien, Pardanaud-Glavieux, Corinne, Sauty-Colace, Claire, Ravassard, Philippe

“…For almost 40 years, pronuclear DNA injection represents the standard method to generate transgenic mice with random integration of transgenes. Such a routine…”
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Lentiviral Mediated Production of Transgenic Mice: A Simple and Highly Efficient Method for Direct Study of Founders by Dussaud, Sébastien, Pardanaud-Glavieux, Corinne, Sauty-Colace, Claire, Ravassard, Philippe

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Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells by Yaniz-Galende, Elisa, Roux, Maguelonne, Nadaud, Sophie, Mougenot, Nathalie, Bouvet, Marion, Claude, Olivier, Lebreton, Guillaume, Blanc, Catherine, Pinet, Florence, Atassi, Fabrice, Perret, Claire, Dierick, France, Dussaud, Sébastien, Leprince, Pascal, Trégouët, David-Alexandre, Marazzi, Giovanna, Sassoon, David, Hulot, Jean-Sébastien

“…Background: Pw1 gene expression is a marker of adult stem cells in a wide range of tissues. PW1-expressing cells are detected in the heart but are not well…”
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Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells by Yaniz-Galende, Elisa, Roux, Maguelonne, Nadaud, Sophie, Mougenot, Nathalie, Bouvet, Marion, Claude, Olivier, Lebreton, Guillaume, Blanc, Catherine, Pinet, Florence, Atassi, Fabrice, Perret, Claire, Dierick, France, Dussaud, Sébastien, Leprince, Pascal, Trégouët, David-Alexandre, Marazzi, Giovanna, Sassoon, David, Hulot, Jean-Sébastien

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Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells by Yaniz-Galende, Elisa, Roux, Maguelonne, Nadaud, Sophie, Mougenot, Nathalie, Bouvet, Marion, Claude, Olivier, Lebreton, Guillaume, Blanc, Catherine, Pinet, Florence, Atassi, Fabrice, Perret, Claire, Dierick, France, Dussaud, Sébastien, Leprince, Pascal, Trégouët, David-Alexandre, Marazzi, Giovanna, Sassoon, David, Hulot, Jean-Sébastien

“…Background: Pw1 gene expression is a marker of adult stem cells in a wide range of tissues. PW1-expressing cells are detected in the heart but are not well…”
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Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells by Yaniz-Galende, Elisa, Roux, Maguelonne, Nadaud, Sophie, Mougenot, Nathalie, Bouvet, Marion, Claude, Olivier, Lebreton, Guillaume, Blanc, Catherine, Pinet, Florence, Atassi, Fabrice, Perret, Claire, Dierick, France, Dussaud, Sébastien, Leprince, Pascal, Trégouët, David-Alexandre, Marazzi, Giovanna, Sassoon, David, Hulot, Jean-Sébastien

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Diaphragmatic dysfunction in SEPN1-related myopathy by Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien

“…Abstract Dynamin-2 is a ubiquitously expressed GTP-ase that mediates membrane remodeling. Recent findings indicate that dynamin-2 also regulates actin…”
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