Search Results - "Dushkin, Alexandr V"
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Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry
Published in Drug delivery (01-11-2018)“…An amorphous solid dispersion (SD) of curcumin (Cur) with disodium glycyrrhizin (Na 2 GA) was prepared by mechanical ball milling. Curcumin loaded micelles…”
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Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats
Published in Frontiers in pharmacology (13-04-2021)“…Oxymatrine (OMT), a quinolizidine alkaloid extracted from traditional Chinese herb Ait, has drawn attention because of its beneficial bioactivities against…”
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3
Preparation of DNC Solid Dispersion by a Mechanochemical Method with Glycyrrhizic Acid and Polyvinylpyrrolidone to Enhance Bioavailability and Activity
Published in Polymers (16-05-2022)“…To exploit aqueous-soluble formulation and improve the anticoccidial activity of 4,4'-dinitrocarbanilide (DNC, active component of nicarbazin), this paper…”
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4
Mechanochemical Magnesium-Mediated Minisci C–H Alkylation of Pyrimidines with Alkyl Bromides and Chlorides
Published in Organic letters (20-08-2021)“…A novel method to synthesize 4-alkylpyrimidines by the mechanochemical magnesium-mediated Minisci reaction of pyrimidine derivatives and alkyl halides has been…”
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5
Inositol hexanicotinate self-micelle solid dispersion is an efficient drug delivery system in the mouse model of non-alcoholic fatty liver disease
Published in International journal of pharmaceutics (01-06-2021)“…[Display omitted] Inositol hexanicotinate (IHN) self-micelle solid dispersion (SD) with glycyrrhizic acid (GA) and arabic gum (AG) was prepared by mechanical…”
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Preparation of camptothecin micelles self-assembled from disodium glycyrrhizin and tannic acid with enhanced antitumor activity
Published in European journal of pharmaceutics and biopharmaceutics (01-07-2021)“…[Display omitted] Natural compounds as carriers for hydrophobic drugs have been increasingly used in drug delivery systems. In this study, disodium…”
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Preparation, physicochemical and pharmacological study of 10-hydroxycamptothecin solid dispersion with complexation agent – xylan-nonanoic acid amphiphilic conjugates
Published in International journal of biological macromolecules (15-04-2022)“…An amphiphilic conjugate of carboxymethyl xylan-nonanoic acid (CX-NA) was synthesized with molecular weight of 38.35 kDa, HLB value of 13.59, and critical…”
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Preparation of protamine-hyaluronic acid coated core-shell nanoparticles for enhanced solubility, permeability, and oral bioavailability of decoquinate
Published in International journal of biological macromolecules (01-10-2022)“…Decoquinate (DQ) has low oral bioavailability owing to its poor water solubility. In this study, a DQ solid dispersion (DQ-SD) was fabricated using…”
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9
Mechanically induced solvent-free esterification method at room temperature
Published in RSC advances (28-01-2021)“…Herein, we describe two novel strategies for the synthesis of esters, as achieved under high-speed ball-milling (HSBM) conditions at room temperature. In the…”
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Preparation, physicochemical and pharmacological study of curcumin solid dispersion with an arabinogalactan complexation agent
Published in International journal of biological macromolecules (01-05-2019)“…Pharmaceutical solid dispersions (SD) of curcumin (Cur) with macromolecule polysaccharide arabinogalactan (AG) from wood of Larix sibirica were prepared by…”
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Mechanochemical preparation of kaempferol intermolecular complexes for enhancing the solubility and bioavailability
Published in Drug development and industrial pharmacy (02-12-2018)“…In this study, complexes of kaempferol (KF) with polysaccharide arabinogalactan (AG) and disodium glycyrrhizinate (Na 2 GA) were prepared through…”
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12
Preparation of olmesartan medoxomil solid dispersion with sustained release performance by mechanochemical technology
Published in Drug delivery and translational research (01-03-2022)“…Hypertension is a common disease for human with high morbidity and mortality, and olmesartan medoxomil (OM) is widely used in the therapy of hypertension…”
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13
The efficacy of the supramolecular complexes of niclosamide obtained by mechanochemical technology and targeted delivery against cestode infection of animals
Published in Veterinary parasitology (15-11-2017)“…•A high efficacy of the supramolecular complex of niclosamide produced by mechanochemical technology and targeted delivery against H. nana in mice.•A high…”
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Polysaccharide arabinogalactan from larch Larix sibirica as carrier for molecules of salicylic and acetylsalicylic acid: preparation, physicochemical and pharmacological study
Published in Drug delivery (01-05-2015)“…Inclusion complexes of salicylic acid (SA) and acetylsalicylic acid (aspirin, ASA) with polysaccharide arabinogalactan (AG) from larch wood Larix sibirica and…”
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Information Security Audit Using Open Source Intelligence Methods
Published in 2022 Conference of Russian Young Researchers in Electrical and Electronic Engineering (ElConRus) (25-01-2022)“…The article shows the possibility of detecting vulnerabilities in the information and telecommunication networks of organizations when conducting an…”
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Conference Proceeding -
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Automation of the Information Collection Process by Osint Methods for Penetration Testing During Information Security Audit
Published in 2022 Conference of Russian Young Researchers in Electrical and Electronic Engineering (ElConRus) (25-01-2022)“…The purpose of this article is to consider one of the options for automating the process of collecting information from open sources when conducting…”
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Conference Proceeding -
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Analysis and Control of the Effectiveness of Information Protection Against Leakage Through Technical Channels Based on Probabilistic Assessment
Published in 2022 Conference of Russian Young Researchers in Electrical and Electronic Engineering (ElConRus) (25-01-2022)“…One of the most important tasks of ensuring the confidentiality of negotiations is to assess the security of acoustic speech information from its leakage…”
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Conference Proceeding -
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Method of Fuzzing Testing of Firewalls Using the Gray Box Method
Published in 2021 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (ElConRus) (26-01-2021)“…This article describes an approach to creating a technique for fuzzing testing firewalls using the gray box method. This method makes it possible to test the…”
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Conference Proceeding -
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Zero-waste utilization and conversion of shrimp shell by mechanochemical method
Published in Journal of cleaner production (01-11-2023)“…In this study, a moderate method for efficient zero-waste utilization and reforming from shrimp shell waste was developed by means of mechanochemistry. The…”
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Preparation of pectin-tannic acid coated core-shell nanoparticle for enhanced bioavailability and antihyperlipidemic activity of curcumin
Published in Food hydrocolloids (01-10-2021)“…As a functional polyphenolic compound, curcumin (CUR) has limited application due to its low solubility and bioavailability. In this work, curcumin loaded…”
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