Search Results - "Dusheiko, Geoff"

Cost–Utility Analysis of Tenofovir Disoproxil Fumarate in the Treatment of Chronic Hepatitis B by Dakin, Helen, MSc, Bentley, Anthony, BSc, Dusheiko, Geoff, MD

“…Abstract Objective The aim of this study was to assess the cost-effectiveness of tenofovir disoproxil fumarate (TDF) in the treatment of chronic hepatitis B…”
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Treatment of chronic hepatitis B virus infection in resource-constrained settings: expert panel consensus by Wiersma, Steven T., McMahon, Brian, Pawlotsky, Jean-Michel, Thio, Chloe L., Thursz, Mark, Lim, Seng Gee, Ocama, Ponsiano, Esmat, Gamal, Maimuna, Mendy, Bell, David, Vitoria, Marco, Eramova, Irina, Lavanchy, Daniel, Dusheiko, Geoff

“…Most of the estimated 350 million people with chronic hepatitis B virus (HBV) infection live in resource‐constrained settings. Up to 25% of those persons will…”
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Cost-Effectiveness Analysis of Alternative Antiviral Strategies for the Treatment of HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B in the United Kingdom by Bermingham, Sarah L., BSc, MSc, Hughes, Ralph, BSc, MSc, Fenu, Elisabetta, MPharm, MSc, Sawyer, Laura M., BSc, MSc, Boxall, Elizabeth, PhD, FRCPath, FFPH, T. Kennedy, Patrick, MB, BCH, BAO, BMedSci, MRCP, MD, Dusheiko, Geoff, MD, MB, BCh, Hill-Cawthorne, Grant, MA, MB, BChir, MRCP, Thomas, Howard, BSc, MB, PhD, FRCP

“…Abstract Background Seven drugs are licensed for the treatment of chronic hepatitis B (CHB) in the United Kingdom. Which initial treatment, secondary therapy,…”
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Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure by Macartney, Malcolm J., Irish, Dianne, Bridge, Simon H., Garcia-Diaz, Ana, Booth, Clare L., McCormick, Adele L., Labbett, Wendy, Smith, Colette, Velazquez, Carmen, Tanwar, Sudeep, Trembling, Paul, Jacobs, Michael, Dusheiko, Geoff, Rosenberg, William, Haque, Tanzina

“…•The development of resistance is detected frequently in patients failing treatment.•Treatment failure is also linked to viral genotype.•IL28B genotype is an…”
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A Genetic Analysis of Hepatitis C Virus Transmission between Injection Drug Users by Cochrane, Alexandra, Searle, Benjamin, Hardie, Alison, Robertson, Roy, Delahooke, Toby, Cameron, Sheila, Tedder, Richard S., Dusheiko, Geoff M., De Lamballerie, Xavier, Simmonds, Peter

“…Hepatitis C virus (HCV) genotype la and 3a partial NS5B gene segment sequences obtained from 154 HCV-infected injection drug users were studied to determine…”
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Frequency and Phenotype of Circulating Vα24/Vβ11 Double-Positive Natural Killer T Cells during Hepatitis C Virus Infection by Lucas, Michaela, Gadola, Stephan, Meier, Ute, Young, Neil T., Harcourt, Gillian, Karadimitris, Anastasios, Coumi, Nikki, Brown, Dave, Dusheiko, Geoff, Cerundolo, Vincenzo, Klenerman, Paul

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human CD1d-Glycolipid Tetramers Generated by in vitro Oxidative Refolding Chromatography by Karadimitris, Anastasios, Gadola, Stephan, Altamirano, Myriam, Brown, Dave, Woolfson, Adrian, Klenerman, Paul, Chen, Ji-Li, Koezuka, Yasuhiko, Irene A. G. Roberts, Price, David A., Dusheiko, Geoff, Milstein, César, Fersht, Alan, Luzzatto, Lucio, Cerundolo, Vincenzo

“…CD1 molecules are specialized in presenting lipids to T lymphocytes, but identification and isolation of CD1-restricted lipid-specific T cells has been…”
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Lamivudine combined with hepatitis B immunoglobulin in for prophylaxis of hepatitis B recurrence after liver transplantation: time for a change? by Deeney, Helena N, Dusheiko, Geoff M

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Micro-elimination of HIV and HCV co-infection by Dusheiko, Geoff, Childs, Kate

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Hepatitis delta genotype 5 is associated with favourable disease outcome and better response to treatment compared to genotype 1 by Spaan, Michelle, Carey, Ivana, Bruce, Matthew, Shang, Dazhuang, Horner, Mary, Dusheiko, Geoff, Agarwal, Kosh

“…Coinfection with HDV causes rapid progression to liver cirrhosis and hepatic decompensation in patients with chronic hepatitis B. Factors that are associated…”
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Suboptimal SVR rates in African patients with atypical genotype 1 subtypes: Implications for global elimination of hepatitis C by Childs, Kate, Davis, Christopher, Cannon, Mary, Montague, Sarah, Filipe, Ana, Tong, Lily, Simmonds, Peter, Smith, Donald, Thomson, Emma C., Dusheiko, Geoff, Agarwal, Kosh

“…[Display omitted] •Unusual genotypes (G1 non 1a/1b or G4 non 4a/4d) were common in African patients.•11 previously unclassified HCV subtypes were represented…”
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High patient acceptability for a hepatitis C mobile outreach service targeting ‘vulnerable’ homeless communities - an important component for elimination? by Montague, Sarah, Sevdalis, Nick, Boufkhed, Sabah, Curtis, Monique, Sekhon, Mandeep, Dusheiko, Geoff, Agarwal, Kosh

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SAT342 - High patient acceptability for a hepatitis C mobile outreach service targeting ‘vulnerable’ homeless communities - an important component for elimination? by Montague, Sarah, Sevdalis, Nick, Boufkhed, Sabah, Curtis, Monique, Sekhon, Mandeep, Dusheiko, Geoff, Agarwal, Kosh

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Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission by Cooke, Graham S, Andrieux-Meyer, Isabelle, Applegate, Tanya L, Atun, Rifat, Burry, Jessica R, Cheinquer, Hugo, Dusheiko, Geoff, Feld, Jordan J, Gore, Charles, Griswold, Max G, Hamid, Saeed, Hellard, Margaret E, Hou, JinLin, Howell, Jess, Jia, Jidong, Kravchenko, Natalia, Lazarus, Jeffrey V, Lemoine, Maud, Lesi, Olufunmilayo A, Maistat, Liudmyla, McMahon, Brian J, Razavi, Homie, Roberts, Teri, Simmons, Bryony, Sonderup, Mark W, Spearman, C Wendy, Taylor, Bridie E, Thomas, David L, Waked, Imam, Ward, John W, Wiktor, Stefan Z

“…Viral hepatitis is a major public health threat and a leading cause of death worldwide. Annual mortality from viral hepatitis is similar to that of other major…”
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Managing HBV in pregnancy. Prevention, prophylaxis, treatment and follow-up: position paper produced by Australian, UK and New Zealand key opinion leaders by Visvanathan, Kumar, Dusheiko, Geoff, Giles, Michelle, Wong, May-Ling, Phung, Nghi, Walker, Susan, Le, Suong, Lim, Seng Gee, Gane, Ed, Ngu, Meng, Hardikar, Winita, Cowie, Ben, Bowden, Scott, Strasser, Simone, Levy, Miriam, Sasaduesz, Joe

“…Hepatitis B during pregnancy presents unique management issues for both the mother and fetus. These include the lack of a current cohesive strategy for…”
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Why do cytotoxic T lymphocytes fail to eliminate hepatitis C virus? Lessons from studies using major histocompatibility complex class I peptide tetramers by Lechner, Franziska, Sullivan, John, Spiegel, Hans, Nixon, Douglas F., Ferrari, Belinda, Davis, Andrew, Borkowsky, Bill, Pollack, Henry, Barnes, Ellie, Dusheiko, Geoff, Klenerman, Paul

“…Hepatitis C virus (HCV) infection is a major public health problem, affecting an estimated 3% of the world's population, and over 10% in some countries…”
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PS-181-Unacceptably low SVR rates in African patients with unusual HCV sub-genotypes : Implications for global elimination by Childs, Kate, Davis, Chris, Cannon, Mary D, Bruce, Matthew, Dusheiko, Geoff, Thomson, Emma, Agarwal, Kosh

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Prevalence of Drug Resistance Associated Substitutions in Persons With Chronic Hepatitis C Infection and Virological Failure Following Initial or Re-treatment With Pan-genotypic Direct-Acting Antivirals: A Systematic Review and Meta-analysis by Inzaule, Seth, Easterbrook, Philippa, Latona, Ashley, Ford, Nathan P, Irving, William, Matthews, Philippa C, Vitoria, Marco, Duncombe, Chris, Giron, Amalia, McCluskey, Suzanne, Lesi, Olufunmilayo, Tchamgoue, Serge, Halford, Rachel, Adda, Danjuma, Thomson, Emma, Dusheiko, Geoff, Jordan, Michael R

“…The advent of short-course, curative treatment with direct-acting antivirals (DAA) has given promise for the global elimination of hepatitis C virus (HCV)…”
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Reply to: “Is resistance to direct-acting antivirals in sub-Saharan Africa a threat to HCV elimination? Recommendations for action” by Childs, Kate, Cannon, Mary, Davis, Christopher, Thompson, Emma C., Dusheiko, Geoff, Agarwal, Kosh

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Prevalence of HIV/hepatitis B and HIV/hepatitis C coinfection among people of East, South, Central and West African ancestry in the United Kingdom by Hung, Rachel, Patel, Nisha, Fox, Julie, Cosgrove, Catherine, Pett, Sarah L., Burns, Fiona, Ustianowski, Andrew, Rosenvinge, Melanie, Bhagani, Sanjay, Dusheiko, Geoff, Childs, Kate, Post, Frank A.

“…Regional variability in the prevalence of hepatitis B (HBV) and C (HCV) is reported in sub-Saharan Africa, although data for people with HIV are sparse. We…”
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